Luck SE, Wieringa JW, Blázquez-Gamero D, Henneke P, Schuster K, Butler K, et al. ESPID Congenital CMV Group Meeting, Leipzig 2015. Congenital Cytomegalovirus: A European Expert Consensus Statement on Diagnosis and Management. Pediatr Infect Dis J. 2017;36(12):1205–13. doi: 10.1097/ INF.0000000000001763.LuckSEWieringaJWBlázquez-GameroDHennekePSchusterKButlerKet alESPID Congenital CMV Group Meeting, Leipzig 20152017361212051310.1097/INF.000000000000176329140947Open DOISearch in Google Scholar
Nijman J, van Loon AM, de Vries LS, Koopman-Esseboom C, Groenendaal F, Uiterwaal CS, et al. Urine viral load and correlation with disease severity in infants with congenital or postnatal cytomegalovirus infection. J Clin Virol. 2012;54(2):121–4. doi: 10.1016/j.jcv.2012.02.017.NijmanJvan LoonAMde VriesLSKoopman-EsseboomCGroenendaalFUiterwaalCSet alUrine viral load and correlation with disease severity in infants with congenital or postnatal cytomegalovirus infection2012542121410.1016/j.jcv.2012.02.01722421537Open DOISearch in Google Scholar
Delforge ML, Costa E, Brancart F, Goldman D, Montesinos I, Zaytouni S, et al. Presence of Cytomegalovirus in urine and blood of pregnant women with primary infection might be associated with fetal infection. J Clin Virol. 2017;90:14–7. doi: 10.1016/j.jcv.2017.03.004.DelforgeMLCostaEBrancartFGoldmanDMontesinosIZaytouniSet alPresence of Cytomegalovirus in urine and blood of pregnant women with primary infection might be associated with fetal infection20179014710.1016/j.jcv.2017.03.00428319846Open DOISearch in Google Scholar
Zavattoni M, Lombardi G, Rognoni V, Furione M, Klersy C, Stronati M, et al. Maternal, fetal, and neonatal parameters for prognosis and counseling of HCMV congenital infection. J Med Virol. 2014;86(12):2163–70. doi: 10.1002/jmv.23954.ZavattoniMLombardiGRognoniVFurioneMKlersyCStronatiMet alMaternal, fetal, and neonatal parameters for prognosis and counseling of HCMV congenital infection2014861221637010.1002/jmv.2395424777597Open DOISearch in Google Scholar
Boppana SB, Ross SA, Fowler KB. Congenital cytomegalovirus infection: clinical outcome. Clin Infect Dis. 2013;57 Suppl 4(Suppl 4):S178–81. doi: 10.1093/cid/cit629.BoppanaSBRossSAFowlerKBCongenital cytomegalovirus infection: clinical outcome201357 Suppl4Suppl 4S1788110.1093/cid/cit629447143824257422Open DOISearch in Google Scholar
Marques M, Ferreira AR, Ribeiro D. The interplay between human cytomegalovirus and pathogen recognition receptor signaling. Viruses. 2018;10(10):514. doi: 10.3390/v10100514.MarquesMFerreiraARRibeiroDThe interplay between human cytomegalovirus and pathogen recognition receptor signaling2018101051410.3390/v10100514621288930241345Open DOISearch in Google Scholar
Fernández-Ruiz M, Corrales I, Arias M, Campistol JM, Giménez E, Crespo J, et al. OPERA Study Group. Association between individual and combined SNPs in genes related to innate immunity and incidence of CMV infection in seropositive kidney transplant recipients. Am J Transplant. 2015;15(5):1323–35. doi: 10.1111/ajt.13107.Fernández-RuizMCorralesIAriasMCampistolJMGiménezECrespoJet alOPERA Study Group201515513233510.1111/ajt.1310725777542Open DOISearch in Google Scholar
Bravo D, Solano C, Giménez E, Remigia MJ, Corrales I, Amat P, et al. Effect of the IL28B Rs12979860 C/T polymorphism on the incidence and features of active cytomegalovirus infection in allogeneic stem cell transplant patients. J Med Virol. 2014;86(5):838– 44. doi: 10.1002/jmv.23865.BravoDSolanoCGiménezERemigiaMJCorralesIAmatPet alEffect of the IL28B Rs12979860 C/T polymorphism on the incidence and features of active cytomegalovirus infection in allogeneic stem cell transplant patients2014865838–4410.1002/jmv.2386524374819Open DOISearch in Google Scholar
Wujcicka W, Paradowska E, Studzińska M, Gaj Z, Wilczyński J, Leśnikowski Z, et al. TLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus. PLoS One. 2015;10(4):e0122831. doi: 10.1371/journal.pone.0122831.WujcickaWParadowskaEStudzińskaMGajZWilczyńskiJLeśnikowskiZet alTLR9 2848 GA heterozygotic status possibly predisposes fetuses and newborns to congenital infection with human cytomegalovirus2015104e012283110.1371/journal.pone.0122831438676125844529Open DOISearch in Google Scholar
Kasztelewicz B, Czech-Kowalska J, Lipka B, Milewska-Bobula B, Borszewska-Kornacka MK, Romańska J, et al. Cytokine gene polymorphism associations with congenital cytomegalovirus infection and sensorineural hearing loss. Eur J Clin Microbiol Infect Dis. 2017;36(10):1811–8. doi: 10.1007/s10096-017-2996-6.KasztelewiczBCzech-KowalskaJLipkaBMilewska-BobulaBBorszewska-KornackaMKRomańskaJet alCytokine gene polymorphism associations with congenital cytomegalovirus infection and sensorineural hearing loss201736101811810.1007/s10096-017-2996-6560208328501927Open DOISearch in Google Scholar
Loeffler J, Steffens M, Arlt EM, Toliat MR, Mezger M, Suk A, et al. Polymorphisms in the genes encoding chemokine receptor 5, interleukin-10, and monocyte chemoattractant protein 1 contribute to cytomegalovirus reactivation and disease after allogeneic stem cell transplantation. J Clin Microbiol. 2006;44(5):1847–50. doi: 10.1128/JCM.44.5.1847-1850.2006.LoefflerJSteffensMArltEMToliatMRMezgerMSukAet alPolymorphisms in the genes encoding chemokine receptor 5, interleukin-10, and monocyte chemoattractant protein 1 contribute to cytomegalovirus reactivation and disease after allogeneic stem cell transplantation200644518475010.1128/JCM.44.5.1847-1850.2006147920516672419Open DOISearch in Google Scholar
Hoffmann TW, Halimi JM, Büchler M, Velge-Roussel F, Goudeau A, Al Najjar A, et al. Association between a polymorphism in the IL-12p40 gene and cytomegalovirus reactivation after kidney transplantation. Transplantation. 2008;85(10):1406–11. doi: 10.1097/TP.0b013e31816c7dc7.HoffmannTWHalimiJMBüchlerMVelge-RousselFGoudeauAAlNajjar Aet alAssociation between a polymorphism in the IL-12p40 gene and cytomegalovirus reactivation after kidney transplantation2008851014061110.1097/TP.0b013e31816c7dc718497679Open DOISearch in Google Scholar
Kijpittayarit S, Eid AJ, Brown RA, Paya CV, Razonable RR. Relationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation. Clin Infect Dis. 2007;44(10):1315–20. doi: 10.1086/514339.KijpittayaritSEidAJBrownRAPayaCVRazonableRRRelationship between Toll-like receptor 2 polymorphism and cytomegalovirus disease after liver transplantation2007441013152010.1086/51433917443468Open DOISearch in Google Scholar
Jedlińska-Pijanowska D, Kasztelewicz B, Czech-Kowalska J, Jaworski M, Charusta-Sienkiewicz K, Dobrzańska A. Association between single nucleotide polymorphisms (SNPs) of IL1, IL12, IL28 and TLR4 and symptoms of congenital cytomegalovirus infection. PLoS One. 2020;15(5):e0233096. doi: 10.1371/journal.pone.0233096.Jedlińska-PijanowskaDKasztelewiczBCzech-KowalskaJJaworskiMCharusta-SienkiewiczKDobrzańskaAAssociation between single nucleotide polymorphisms (SNPs) of IL1, IL12, IL28 and TLR4 and symptoms of congenital cytomegalovirus infection2020155e023309610.1371/journal.pone.0233096723358332421725Open DOISearch in Google Scholar
Chéneau C, Coulon F, Porkolab V, Fieschi F, Laurant S, Razanajaona-Doll D, et al. Fine mapping the interaction between dendritic cell-specific intercellular adhesion molecule (ICAM)-3-grabbing nonintegrin and the cytomegalovirus envelope glycoprotein B. J Infect Dis. 2018;218(3):490–503. doi: 10.1093/infdis/jiy194.ChéneauCCoulonFPorkolabVFieschiFLaurantSRazanajaona-DollDet alFine mapping the interaction between dendritic cell-specific intercellular adhesion molecule (ICAM)-3-grabbing nonintegrin and the cytomegalovirus envelope glycoprotein B2018218349050310.1093/infdis/jiy194604902529648611Open DOISearch in Google Scholar
Compton T, Kurt-Jones EA, Boehme KW, Belko J, Latz E, Golenbock DT, et al. Human cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2. J Virol. 2003;77(8):4588–96. doi: 10.1128/jvi.77.8.4588-4596.2003.ComptonTKurt-JonesEABoehmeKWBelkoJLatzEGolenbockDTet alHuman cytomegalovirus activates inflammatory cytokine responses via CD14 and Toll-like receptor 2200377845889610.1128/jvi.77.8.4588-4596.200315213012663765Open DOISearch in Google Scholar
Paradowska E, Jabłońska A, Studzińska M, Skowrońska K, Suski P, Wiśniewska-Ligier M, et al. TLR9 -1486T/C and 2848C/T SNPs are associated with human cytomegalovirus infection in infants. PLoS One. 2016;11(4):e0154100. doi: 10.1371/journal.pone.0154100ParadowskaEJabłońskaAStudzińskaMSkowrońskaKSuskiPWiśniewska-LigierMet alTLR9 -1486T/C and 2848C/T SNPs are associated with human cytomegalovirus infection in infants2016114e015410010.1371/journal.pone.0154100484155327105145Open DOISearch in Google Scholar
Wujcicka W, Paradowska E, Studzińska M, Wilczyński J, Nowakowska D. TLR2 2258 G<A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus. Virol J. 2017;14(1):12. doi: 10.1186/s12985-016-0679-z.WujcickaWParadowskaEStudzińskaMWilczyńskiJNowakowskaDTLR2 2258 G<A single nucleotide polymorphism and the risk of congenital infection with human cytomegalovirus20171411210.1186/s12985-016-0679-z526004928118851Open DOISearch in Google Scholar
Yew KH, Carpenter C, Duncan RS, Harrison CJ. Human cytomegalovirus induces TLR4 signaling components in monocytes altering TIRAP, TRAM and downstream interferon-beta and TNF-alpha expression. PLoS One. 2012;7(9):e44500. doi: 10.1371/journal.pone.0044500.YewKHCarpenterCDuncanRSHarrisonCJHuman cytomegalovirus induces TLR4 signaling components in monocytes altering TIRAP, TRAM and downstream interferon-beta and TNF-alpha expression201279e4450010.1371/journal.pone.0044500343689422970235Open DOISearch in Google Scholar
Egli A, Levin A, Santer DM, Joyce M, O’Shea D, Thomas BS, et al. Immunomodulatory Function of Interleukin 28B during primary infection with cytomegalovirus. J Infect Dis. 2014;210(5):717–27. doi: 10.1093/infdis/jiu144.EgliALevinASanterDMJoyceMO’SheaDThomasBSet alImmunomodulatory Function of Interleukin 28B during primary infection with cytomegalovirus201421057172710.1093/infdis/jiu14424620020Open DOISearch in Google Scholar
Wujcicka W, Wilczyński J, Paradowska E, Studzińska M, Nowakowska D. The role of single nucleotide polymorphisms, contained in proinflammatory cytokine genes, in the development of congenital infection with human cytomegalovirus in fetuses and neonates. Microb Pathog. 2017;105:106–16. doi: 10.1016/j.mic-path.2017.02.017.WujcickaWWilczyńskiJParadowskaEStudzińskaMNowakowskaDThe role of single nucleotide polymorphisms, contained in proinflammatory cytokine genes, in the development of congenital infection with human cytomegalovirus in fetuses and neonates20171051061610.1016/j.mic-path.2017.02.017Open DOISearch in Google Scholar
Hamilton ST, Scott G, Naing Z, Iwasenko J, Hall B, Graf N, et al. Human cytomegalovirus-induces cytokine changes in the placenta with implications for adverse pregnancy outcomes. PLoS One. 2012;7(12):e52899. doi: 10.1371/journal.pone.0052899.HamiltonSTScottGNaingZIwasenkoJHallBGrafNet alHuman cytomegalovirus-induces cytokine changes in the placenta with implications for adverse pregnancy outcomes2012712e5289910.1371/journal.pone.0052899353411823300810Open DOISearch in Google Scholar
Solé X, Guinó E, Valls J, Iniesta R, Moreno V. SNPStats: a web tool for the analysis of association studies. Bioinformatics. 2006;22(15):1928–9. doi: 10.1093/bioinformatics/btl268.SoléXGuinóEVallsJIniestaRMorenoVSNPStats: a web tool for the analysis of association studies200622151928910.1093/bioinformatics/btl26816720584Open DOISearch in Google Scholar
Popescu I, Pipeling MR, Mannem H, Shah PD, Orens JB, Connors M, et al. IL-12-dependent cytomegalovirus-specific CD4+ T cell proliferation, T-bet induction, and effector multifunction during primary infection are key determinants for early immune control. J Immunol. 2016;196(2):877–90. doi: 10.4049/jimmunol.1501589.PopescuIPipelingMRMannemHShahPDOrensJBConnorsMet alIL-12-dependent cytomegalovirus-specific CD4+ T cell proliferation, T-bet induction, and effector multifunction during primary infection are key determinants for early immune control201619628779010.4049/jimmunol.1501589470707426663780Open DOISearch in Google Scholar
Song J, Zhang Q, Wang R, Sun M, Jin S. Associations of IL-12, IL12R polymorphisms and serum IL-12 levels with high-risk human papillomavirus susceptibility in rural women from Luohe, Henan, China. Medicine (Baltimore). 2019;98(38):e16991. doi: 10.1097/MD.0000000000016991.SongJZhangQWangRSunMJinSAssociations of IL-12, IL12R polymorphisms and serum IL-12 levels with high-risk human papillomavirus susceptibility in rural women from Luohe, Henan, China20199838e1699110.1097/MD.0000000000016991675672231567936Open DOISearch in Google Scholar
Saxena R, Chawla YK, Verma I, Kaur J. Effect of IL-12B, IL-2, TGF- β1, and IL-4 polymorphism and expression on hepatitis B progression. J Interferon Cytokine Res. 2014;34(2):117–28. doi: 10.1089/jir.2013.0043.SaxenaRChawlaYKVermaIKaurJEffect of IL-12B, IL-2, TGF- β1, and IL-4 polymorphism and expression on hepatitis B progression20143421172810.1089/jir.2013.004324161121Open DOISearch in Google Scholar
Mueller T, Mas-Marques A, Sarrazin C, Wiese M, Halangk J, Witt H, et al. Influence of interleukin 12B (IL12B) polymorphisms on spontaneous and treatment-induced recovery from hepatitis C virus infection. J Hepatol. 2004;41(4):652–8. doi: 10.1016/j.jhep.2004.06.021.MuellerTMas-MarquesASarrazinCWieseMHalangkJWittHet alInfluence of interleukin 12B (IL12B) polymorphisms on spontaneous and treatment-induced recovery from hepatitis C virus infection2004414652810.1016/j.jhep.2004.06.02115464247Open DOISearch in Google Scholar
Hoffmann TW, Halimi JM, Büchler M, Velge-Roussel F, Goudeau A, Al-Najjar A, et al. Association between a polymorphism in the human programmed death-1 (PD-1) gene and cytomegalovirus infection after kidney transplantation. J Med Genet. 2010;47(1):54–8. doi: 10.1136/jmg.2009.068841.HoffmannTWHalimiJMBüchlerMVelge-RousselFGoudeauAAl-NajjarAet alAssociation between a polymorphism in the human programmed death-1 (PD-1) gene and cytomegalovirus infection after kidney transplantation201047154810.1136/jmg.2009.06884119581275Open DOISearch in Google Scholar
Seegers D, Zwiers A, Strober W, Peña AS, Bouma G. A TaqI polymorphism in the 3’UTR of the IL-12 p40 gene correlates with increased IL-12 secretion. Genes Immun. 2002;3(7):419–23. doi: 10.1038/sj.gene.6363919.SeegersDZwiersAStroberWPeñaASBoumaGA TaqI polymorphism in the 3’UTR of the IL-12 p40 gene correlates with increased IL-12 secretion2002374192310.1038/sj.gene.636391912424624Open DOISearch in Google Scholar
Wei-Lu, Chen SJ, Huang SF, Chan YJ, Wang FD, Chen HP. Clinical significance of human cytomegalovirus viruria and the effect of antiviral therapy in hematopoietic stem cell transplant recipients. J Microbiol Immunol Infect. 2019;52(3):402–8. doi: 10.1016/j.jmii.2017.08.019.Wei-LuChenSJHuangSFChanYJWangFDChenHPClinical significance of human cytomegalovirus viruria and the effect of antiviral therapy in hematopoietic stem cell transplant recipients2019523402810.1016/j.jmii.2017.08.01929126804Open DOISearch in Google Scholar
Gabrielli L, Bonasoni MP, Santini D, Piccirilli G, Chiereghin A, Petrisli E, et al. Congenital cytomegalovirus infection: patterns of fetal brain damage. Clin Microbiol Infect. 2012;18(10):E419–27. doi: 10.1111/j.1469-0691.2012.03983.x.GabrielliLBonasoniMPSantiniDPiccirilliGChiereghinAPetrisliEet alCongenital cytomegalovirus infection: patterns of fetal brain damage20121810E4192710.1111/j.1469-0691.2012.03983.x22882294Open DOISearch in Google Scholar
Kimberlin DW, Acosta EP, Sánchez PJ, Sood S, Agrawal V, Homans J, et al. National Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group. Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease. J Infect Dis. 2008;197(6):836–45. doi: 10.1086/528376.KimberlinDWAcostaEPSánchezPJSoodSAgrawalVHomansJet alNational Institute of Allergy and Infectious Diseases Collaborative Antiviral Study Group200819768364510.1086/52837618279073Open DOISearch in Google Scholar
Lanari M, Lazzarotto T, Venturi V, Papa I, Gabrielli L, Guerra B, et al. Neonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic congenitally infected newborns. Pediatrics. 2006;117(1):e76–83. doi: 10.1542/peds.2005-0629. Erratum in: Pediatrics. 2006 Apr;117(4):1467LanariMLazzarottoTVenturiVPapaIGabrielliLGuerraBet alNeonatal cytomegalovirus blood load and risk of sequelae in symptomatic and asymptomatic congenitally infected newborns20061171e768310.1542/peds.2005-0629Erratum in: Pediatrics. 2006 Apr;117(4):146716326692Open DOISearch in Google Scholar
Walter S, Atkinson C, Sharland M, Rice P, Raglan E, Emery VC, et al. Congenital cytomegalovirus: association between dried blood spot viral load and hearing loss. Arch Dis Child Fetal Neonatal Ed. 2008;93(4):F280–5. doi: 10.1136/adc.2007.119230.WalterSAtkinsonCSharlandMRicePRaglanEEmeryVCet alCongenital cytomegalovirus: association between dried blood spot viral load and hearing loss2008934F280510.1136/adc.2007.11923018039747Open DOISearch in Google Scholar
Smiljkovic M, Le Meur JB, Malette B, Boucoiran I, Minsart AF, Lamarre V, et al. Blood viral load in the diagnostic workup of congenital cytomegalovirus infection. J Clin Virol. 2020;122:104231. doi: 10.1016/j.jcv.2019.104231.SmiljkovicMLe MeurJBMaletteBBoucoiranIMinsartAFLamarreVet alBlood viral load in the diagnostic workup of congenital cytomegalovirus infection202012210423110.1016/j.jcv.2019.10423131821950Open DOISearch in Google Scholar
Marsico C, Aban I, Kuo H, James SH, Sanchez PJ, Ahmed A, et al. Collaborative Antiviral Study Group (CASG). Blood Viral Load in Symptomatic Congenital Cytomegalovirus Infection. J Infect Dis. 2019;219(9):1398–406. doi: 10.1093/infdis/jiy695.MarsicoCAbanIKuoHJamesSHSanchezPJAhmedAet alCollaborative Antiviral Study Group (CASG)20192199139840610.1093/infdis/jiy695646718730535363Open DOISearch in Google Scholar
Ross SA, Novak Z, Fowler KB, Arora N, Britt WJ, Boppana SB. Cytomegalovirus blood viral load and hearing loss in young children with congenital infection. Pediatr Infect Dis J. 2009;28(7):588–92. doi: 10.1097/INF.0b013e3181979a27.RossSANovakZFowlerKBAroraNBrittWJBoppanaSBCytomegalovirus blood viral load and hearing loss in young children with congenital infection20092875889210.1097/INF.0b013e3181979a27303321419478688Open DOISearch in Google Scholar
Studzińska M, Jabłońska A, Wiśniewska-Ligier M, Nowakowska D, Gaj Z, Leśnikowski ZJ, et al. Association of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children. PLoS One. 2017;12(1):e0169420. doi: 10.1371/journal.pone.0169420.StudzińskaMJabłońskaAWiśniewska-LigierMNowakowskaDGajZLeśnikowskiZJet alAssociation of TLR3 L412F Polymorphism with Cytomegalovirus Infection in Children2017121e016942010.1371/journal.pone.0169420520778328046022Open DOISearch in Google Scholar
https://www.ncbi.nlm.nih.gov/snp/. Reference SNP (rs) Report.https://www.ncbi.nlm.nih.gov/snp/Search in Google Scholar