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Severe enterovirus infections in infants <3 months of age and the importance of medical history

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Table 1

No. Month of admission Age Family history Symptoms on admission CRP [mg/L] PCT [ng/mL] Leucocytes [/uL] Neutrophils [%] Lymphocytes [%] CSF cytosis [cells/ Mononuclear cells in CSF [%] Multinuclear cells in CSF Glucose in CSF [mmol/L] Protein in CSF [g/L] Lactic acid in CSF [mmol/L] Where infection has been confirmed TroponinT [ng/L] Antibiotics HSV in CSF Neuroimaging
1. Il 0/365 Child's mother has fever Respiratory failure, prematurity 7.9 0.93 8310 60.1 24.4 Examinations not performed Faeces, tissue biopsy Examinations not performed Ampicillin, amikin, meropenem, vancomycin Samples not collected Ultrasound scan - normal before the septic shock
2. X 1/365 Father had hand, foot and mouth disease about month 1 earlier, mother was vomiting on the day she gave birth Respiratory and circulatory insufficiency, arrhythmia, ascites <5 Not performed 8370 64.3 22.1 Examinations not performed Mother's stool 254.7 Ampicillin, amikin, aciclovir Samples not collected MRI-features of (minor) intramuscular bleeding and minor haemorrhagic lesions of the cerebellum and the right lobe. Features of immaturity of the white brain matter. There were no signs of encephalitis, (prematurity 29 hbd)
3. II 19/365 His father had been feverish a few days earlier, older his brother had infection of the upper respiratory tract Fever, seizures (tonic seizure, strabismus, pushing out the tongue) <5 0.12 19770 32.4 51.5 1910 98.9 1.1 2 1.22 1.5 Stoo 50.1 Cephotaxim, ampicillin, aciclovir Negative Ultrasound-thalamostriate vasculopathy
4. VI 6/52 No data Fever, hyperesthesia, abdominal distension 11.2 0.15 9170 45.2 41.9 693 53.3 46.7 3 2.02 1.4 Stool 32.4 Ceftriaxone, amikacin, aciclovir Negative Ultrasound-normal
5. VII 7/52 Members of the household with symptoms of viral infection Fever, lack of appetite, apathy 5.9 0.16 13000 32.4 47.8 673 27.5 72.5 3 0,76 1.4 Stool Examinations not performed Cephotaxim, amikacin, vancomycin, ceftriaxone, aciclovir Negative MRI-normal
6. X 6/52 No data Fever, hyperesthesia, difficulty in Eating <5 0.16 3460 26.3 43.6 2 100 0 3 0.52 1.4 CSF Examinations not performed No. Negative Ultrasound-normal
7. XI 1/12 Older siblings had upper respiratory tract infections Older sister had Fever, lack of appetite, apathy 6,6 0.17 12290 48.3 39.3 530 98.7 1.3 2 1.12 1.1 Stool Examinations not performed Ceftriaxone, amikin, fluconazole No data Ultrasound-normal
8. XII 1/12 upper respiratory tract infection Fever, apathy £5 0.11 11380 22.2 57.3 698 94.7 5.3 2 1.2 1.7 CSF Examinations not performed Ampicillin, amikacin, aciclovir No data Ultrasound-normal
9. 7/365 Father had pharyngitis Fever, apathy, difficulty in Eating <5 0.2 13910 30.4 53.9 492 97.5 2.5 2 1.21 1.2 CSF Examinations not performed Aciclovir Negative MRI-normal
10. X 7/52 No data Fever, apathy, difficulty in Eating 10.7 0.18 10390 14.9 71.9 Examinations not performed Stool 329.2 Cefuroxime Sampies not collected Ultrasound-normal
eISSN:
2719-535X
Lingua:
Inglese
Frequenza di pubblicazione:
Volume Open
Argomenti della rivista:
Medicine, Clinical Medicine, Pediatrics and Juvenile Medicine, Paediatric Haematology and Oncology, Public Health