<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_jmotherandchild.20202403.2022.d-20-00007_s_009">
<h3>Background</h3>
<p>Enteroviral infections in infants &lt;3 months of age are frequent and under-diagnosed even though they can be life-threatening. Properly conducted subjective examination, which is repeatedly neglected, plays a key role in the diagnosis and treatment of these infections.</p>
</sec>
<sec id="j_jmotherandchild.20202403.2022.d-20-00007_s_010">
<h3>Materials and methods</h3>
<p>Analyses included children &lt;3 months of age with confirmed enterovirus infection, hospitalised in the Department of Paediatrics from January 2019 to February 2020. Infections were confirmed by reverse transcription polymerase chain reaction in the cerebrospinal fluid using Neuro9 FTD set and in the stool using PB-03/Neuro; antibodies were determined in one patient.</p>
</sec>
<sec id="j_jmotherandchild.20202403.2022.d-20-00007_s_011">
<h3>Results</h3>
<p>This study presents a detailed description of three cases with confirmed enterovirus infection and a positive epidemiological history. The cases involve viral sepsis, myocarditis with arrhythmia and circulatory failure, and meningitis with seizures. In addition, the details of 10 patients hospitalised in the Children’s Clinic with a confirmed enterovirus infection are presented. Based on these cases, a significant influence of family history-taking on the diagnosis and implementation of appropriate treatment was found.</p>
</sec>
<sec id="j_jmotherandchild.20202403.2022.d-20-00007_s_012">
<h3>Conclusion</h3>
<p>In most of the analysed cases, family history of viral infection was positive. In patients with the most severe course of the enterovirus infection, accurate epidemiological history is extremely important, and the suspicion of viral infection and securing appropriate materials for testing may significantly speed up the diagnosis in the newborn and help to implement an appropriate treatment.</p>
</sec>
</abstract>

Background
Enteroviral infections in infants <3 months of age are frequent and under-diagnosed even though they can be life-threatening. Properly conducted subjective examination, which is repeatedly neglected, plays a key role in the diagnosis and treatment of these infections.


Materials and methods
Analyses included children <3 months of age with confirmed enterovirus infection, hospitalised in the Department of Paediatrics from January 2019 to February 2020. Infections were confirmed by reverse transcription polymerase chain reaction in the cerebrospinal fluid using Neuro9 FTD set and in the stool using PB-03/Neuro; antibodies were determined in one patient.


Results
This study presents a detailed description of three cases with confirmed enterovirus infection and a positive epidemiological history. The cases involve viral sepsis, myocarditis with arrhythmia and circulatory failure, and meningitis with seizures. In addition, the details of 10 patients hospitalised in the Children’s Clinic with a confirmed enterovirus infection are presented. Based on these cases, a significant influence of family history-taking on the diagnosis and implementation of appropriate treatment was found.


Conclusion
In most of the analysed cases, family history of viral infection was positive. In patients with the most severe course of the enterovirus infection, accurate epidemiological history is extremely important, and the suspicion of viral infection and securing appropriate materials for testing may significantly speed up the diagnosis in the newborn and help to implement an appropriate treatment.

Severe enterovirus infections in infants &lt;3 months of age and the importance of medical history

Journal of Mother and Child

This work is licensed under the Creative Commons Attribution 4.0 International License.

Severe enterovirus infections in infants <3 months of age and the importance of medical history

Background
Enteroviral infections in infants <3 months of age are frequent and under-diagnosed even though they can be life-threatening. Properly conducted...

Severe enterovirus infections in infants <3 months of age and the importance of medical history

Article Category: Clinical report

Pubblicato online: 29 gen 2021

Pagine: 37 - 44

DOI: https://doi.org/10.34763/jmotherandchild.20202403.2022.d-20-00007

Parole chiave
enteroviruses, viral sepsis, newborns, infants 3 months old

© 2020 Anna Olchawa-Czech et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Severe enterovirus infections in infants <3 months of age and the importance of medical history

Article Category: Clinical report

Pubblicato online: 29 gen 2021

Pagine: 37 - 44

DOI: https://doi.org/10.34763/jmotherandchild.20202403.2022.d-20-00007

Parole chiaveenteroviruses, viral sepsis, newborns, infants 3 months old

© 2020 Anna Olchawa-Czech et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Parole chiave
enteroviruses, viral sepsis, newborns, infants 3 months old