The state of immunity in pregnancies complicated by intrauterine infection of the fetus
e | 02 gen 2018
INFORMAZIONI SU QUESTO ARTICOLO
Article Category: Original articles/Prace oryginalne
Pubblicato online: 02 gen 2018
Pagine: 384 - 389
Ricevuto: 01 feb 2017
Accettato: 11 ott 2017
DOI: https://doi.org/10.34763/devperiodmed.20172104.384389
© 2017 Nikolay A. Shcherbina, Liudmyla А. Vygivska, published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
The state of humoral immunity and nonspecific resistance of the peripheral blood in subjected pts (Мe; LQ- UQ).
| Indices | Comparison group (n = 93) | Study group (n = 157) | Control group (n = 50) |
|---|---|---|---|
| Ig M g/l | 1.68 (1.36-2.00) | 1.92*(1.44-2.40) | 1.21 (0.98-1.44) |
| Ig G g/l | 12.1 (9.74-14.46) | 12.98 (11.10-14.86) | 12.3(10.60-15.11) |
| Circulating immune complexes,conventional units of optical density(explain shortcuts) | 79.0 (38.5-109.5) | 105.5* (81.6-129.4) | 65.0 (44.0-67.0) |
| Phagocytic number % | 88.0 (82.0 92.0) | 92.0 (90.0-94.0) | 89.0 (84.0- 90.0) |
| Phagocytizing neutrophils, st.un | 4.4 (3.3-4.6) | 4.3 (4.2- 4.7) | 3.9 (3.3-4.4) |
| Bactericidal activity of neutrophils, % | 37.7 (35.4-38.8) | 39.9 (39.0-40.9) | 37.7 (36.4-38.9) |
| Index of phagocytosis completeness, st. un.>1.0 | 0.94 (0.85- 0.99) | 0.84*(0.72-0.93) | 1.15 (0.98-1.4) |
Phenotypic characteristics of lymphocytes and concentration of cytokines in the peripheral blood of pregnant in subjected pts (Me; LQ-UQ).
| Indices | Comparison group (n=93) | Study group (n= ..157.) | Control group (n=50) |
|---|---|---|---|
| Т-total lymphocytes – (CD3+) (%) | 72.4 (65.8-77.2) | 68.8 (58.2-77.0) | 75.5 (70.5-78.4) |
| Т-helpers/inducers- (CD3+/CD4+) (%) | 40.8 (35.9-50.8) | 32.3* (30.3-38.7) | 47.2 (39.4-53.8) |
| Т-supressors/cytotoxic (CD3+/CD8+ ) (%) | 22.2 (18.3-33.0) | 20.8 (16.5-33.6) | 24.3 (23.5-32.5) |
| В –lymphocytes (СD19+) (%) | 10.0 (7.7-14.7) | 10.8 (7.0-13.0) | 10.5 (9.7-13.5) |
| ТNK-lymphocytes |
7.6* (4.0-11.0) | 9.8* (6.7-12.1) | 5.5 (4.5-6.3) |
| NK –lymphocytes (CD3- CD16+/CD56+) ( %) | 3.9 (2.6-7.5) | 4.3 (3.1-7.7) | 4.0 (2.5-7.4) |
| Т-activated lymphocytes |
3.9 (2.6-7.5) | 4.3 (3.1-7.7) | 4.0 (2.5-7.4) |
| IL-1β pg/ml | 18.8(9.8-20.3) | 31.6* (24.1-42.6) | 6.2 (0-8.5) |
| IL-6, pg/ml | 12.4* (9.3-16.3) | 20.6*(17.2-24.1) | 5.2 (0 - 8.2) |
| IL-10, pg/ml | 10.8 (9.6-15.5) | 4.2*(0.1-5.0) | 15.5(12.5-20.5) |
| TNFα pg/ml | 56.1 (52.2-61.3) | 70.8*(61.6-72.7) | 34.6(28.1-42.4) |