The state of immunity in pregnancies complicated by intrauterine infection of the fetus
et | 02 janv. 2018
À propos de cet article
Article Category: Original articles/Prace oryginalne
Publié en ligne: 02 janv. 2018
Pages: 384 - 389
Reçu: 01 févr. 2017
Accepté: 11 oct. 2017
DOI: https://doi.org/10.34763/devperiodmed.20172104.384389
© 2017 Nikolay A. Shcherbina, Liudmyla А. Vygivska, published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.
The state of humoral immunity and nonspecific resistance of the peripheral blood in subjected pts (Мe; LQ- UQ).
| Indices | Comparison group (n = 93) | Study group (n = 157) | Control group (n = 50) |
|---|---|---|---|
| Ig M g/l | 1.68 (1.36-2.00) | 1.92*(1.44-2.40) | 1.21 (0.98-1.44) |
| Ig G g/l | 12.1 (9.74-14.46) | 12.98 (11.10-14.86) | 12.3(10.60-15.11) |
| Circulating immune complexes,conventional units of optical density(explain shortcuts) | 79.0 (38.5-109.5) | 105.5* (81.6-129.4) | 65.0 (44.0-67.0) |
| Phagocytic number % | 88.0 (82.0 92.0) | 92.0 (90.0-94.0) | 89.0 (84.0- 90.0) |
| Phagocytizing neutrophils, st.un | 4.4 (3.3-4.6) | 4.3 (4.2- 4.7) | 3.9 (3.3-4.4) |
| Bactericidal activity of neutrophils, % | 37.7 (35.4-38.8) | 39.9 (39.0-40.9) | 37.7 (36.4-38.9) |
| Index of phagocytosis completeness, st. un.>1.0 | 0.94 (0.85- 0.99) | 0.84*(0.72-0.93) | 1.15 (0.98-1.4) |
Phenotypic characteristics of lymphocytes and concentration of cytokines in the peripheral blood of pregnant in subjected pts (Me; LQ-UQ).
| Indices | Comparison group (n=93) | Study group (n= ..157.) | Control group (n=50) |
|---|---|---|---|
| Т-total lymphocytes – (CD3+) (%) | 72.4 (65.8-77.2) | 68.8 (58.2-77.0) | 75.5 (70.5-78.4) |
| Т-helpers/inducers- (CD3+/CD4+) (%) | 40.8 (35.9-50.8) | 32.3* (30.3-38.7) | 47.2 (39.4-53.8) |
| Т-supressors/cytotoxic (CD3+/CD8+ ) (%) | 22.2 (18.3-33.0) | 20.8 (16.5-33.6) | 24.3 (23.5-32.5) |
| В –lymphocytes (СD19+) (%) | 10.0 (7.7-14.7) | 10.8 (7.0-13.0) | 10.5 (9.7-13.5) |
| ТNK-lymphocytes |
7.6* (4.0-11.0) | 9.8* (6.7-12.1) | 5.5 (4.5-6.3) |
| NK –lymphocytes (CD3- CD16+/CD56+) ( %) | 3.9 (2.6-7.5) | 4.3 (3.1-7.7) | 4.0 (2.5-7.4) |
| Т-activated lymphocytes |
3.9 (2.6-7.5) | 4.3 (3.1-7.7) | 4.0 (2.5-7.4) |
| IL-1β pg/ml | 18.8(9.8-20.3) | 31.6* (24.1-42.6) | 6.2 (0-8.5) |
| IL-6, pg/ml | 12.4* (9.3-16.3) | 20.6*(17.2-24.1) | 5.2 (0 - 8.2) |
| IL-10, pg/ml | 10.8 (9.6-15.5) | 4.2*(0.1-5.0) | 15.5(12.5-20.5) |
| TNFα pg/ml | 56.1 (52.2-61.3) | 70.8*(61.6-72.7) | 34.6(28.1-42.4) |