HLA Class II-DRB,-DQA and –DQB Genotypes in Peripheral Blood Shows Shifts During the Course of Sepsis

Angus, D. C., van der Poll, T. (2013). Severe sepsis and septic shock. New Engl. J. Med., 369, 840–851.10.1056/NEJMra1208623Search in Google Scholar

Angus, D. C. (2010). The lingering consequences of sepsis: A hidden public health disaster? JAMA,304 (16), 1833–1834.10.1001/jama.2010.1546Search in Google Scholar

Annane, D., Bellissant, E., Cavaillon, J. M. (2005). Septic shock. Lancet, 36, 63–78.10.1016/S0140-6736(04)17667-8Search in Google Scholar

Anonymous (2018a). Nomenclature for factors of the HLA system. Available at: http://hla.alleles.org/nomenclature/index.html (accessed 07.01.2019).Search in Google Scholar

Anonymous (2016). QIAamp DNA Mini and Blood Mini Handbook – 372 EN. Avalaible at: http://www.qiagen.com/ (accessed 09.01.2019).Search in Google Scholar

Anonymous (2018b). Handbook – HLA -DRB1; DQA1; DQB1 kits EN. Avalaible at: http://www.dna-technology.ru/ (accessed 09.01.2019).Search in Google Scholar

Blackwell, J. M., Jamieson, S. E., Burgner, D. (2009). HLA and infectious diseases. Clin. Microbiol. Rev.,22, 370–385.10.1128/CMR.00048-08Search in Google Scholar

Burgner, D., Jamieson, S. E., Blackwell, J. M. (2006). Genetic susceptibility to infectious diseases: Big is beautiful, but will bigger be even better? Lancet Infect Dis., 6 (10), 653–663.10.1016/S1473-3099(06)70601-6Search in Google Scholar

Burton, P. R., Tobin, M. D., Hopper, J. L. (2005). Key concepts in genetic epidemiology. Lancet,366, 941–951.10.1016/S0140-6736(05)67322-9Search in Google Scholar

Cajander, S., Tina, E., Bäckman, A., Magnuson, A., Strålin, K., Söderquist, B., Källman, J. (2016). Quantitative real-time polymerase chain reaction measurement of HLA-DRA gene expression in whole blood is highly reproducible and shows changes that reflect dynamic shifts in monocyte surface HLA-DR expression during the course of sepsis. PLoS One, 11 (5), e0154690.10.1371/journal.pone.0154690485638527144640Search in Google Scholar

Cajander, S., Bäckman, A., Tina, E., Stralin, K., Bo Soderquist, Kallman, J. (2013). Preliminary results in quantitation of HLA-DRA by real-time PCR: A promising approach to identify immunosuppression in sepsis. Crit. Care,17 (5), R223.10.1186/cc13046405720224093602Search in Google Scholar

Cazalis, M. A., Friggeri, A., Cavé, L., Demaret, J., Barbalat, V., Cerrato, E., Lepape, A., Pachot, A., Monneret, G., Venet, F. (2013). Decreased HLA-DR antigen-associated invariant chain (CD74) mRNA expression predicts mortality after septic shock. Crit. Care,17 (6), R287.10.1186/cc13150405600324321376Search in Google Scholar

Cazalis, M. A., Lepape, A., Venet, F., Frager, F., Mougin, B., Vallin, H., Paye, M., Pachot, A., Monneret, G. (2014). Early and dynamic changes in gene expression in septic shock patients: A genome-wide approach. Intensive Care Med. Exp., 2 (1), 20.10.1186/s40635-014-0020-3451299626215705Search in Google Scholar

Choi, N. M., Majumder, P., Boss, J. M. (2011). Regulation of major histocompatibility complex class II genes. Curr. Opin. Immunol., 23 (1), 81–87.10.1016/j.coi.2010.09.007303399220970972Search in Google Scholar

Eglite, J., Hagina, E., Pavare, J., Grope, I., Gardovska, D., Sochnevs, A. (2010). Polymorphisms of HLA-DRB1* locus and the associations with HMGB1 protein in children with SIRS and sepsis. RSU Research Articles in Medicine & Pharmacy. Rīga Stradiņš University, Rīga, pp. 14–18.Search in Google Scholar

Fisher, C. J. Jr., Agosti, J. M., Opal, S. M., Lowry, S. F., Balk, R. A., Sadoff, J. C., Abraham, E., Schein, R. M., Benjamin, E. (1996). Treatment of septic shock with the tumor necrosis factor receptor: Fc fusion protein. The Soluble TNF Receptor Sepsis Study Group. New Engl. J. Med., 334 (26), 1697–1702.10.1056/NEJM199606273342603Search in Google Scholar

Hanna, S., Etzioni, A. (2014). MHC class I and II deficiencies. J. Allergy Clin. Immunol., 134, 269–275.10.1016/j.jaci.2014.06.00125001848Search in Google Scholar

Horton, R., Gibson, R., Coggill, P., Miretti, M., Allcock, R. J., Almeida, J., Forbes, S., Gilbert, J. G., Halls, K., Harrow, J. L., Hart, E., Howe, K., Jackson, D. K., Palmer, S., Roberts, A. N., Sims, S., Stewart, C. A., Traherne, J. A., Trevanion, S., Wilming, L., Rogers, J., de Jong P. J., Elliott, J. F., Sawcer, S., Todd, J. A., Trowsdale, J., Beck, S. (2008). Variation analysis and gene annotation of eight MHC haplotypes: The MHC Haplotype Project. Immunogenetics,60 (1), 1–18.10.1007/s00251-007-0262-2220624918193213Search in Google Scholar

Hotchkiss, R. S., Karl, I. E. (2003). The pathophysiology and treatment of sepsis. New Engl. J. Med., 17, 138–150.10.1056/NEJMra02133312519925Search in Google Scholar

Jabandziev, P., Smerek, M., Michalek, J., Fedora, M., Kosinova, L., Hubacek, J. A., Michalek, J. (2014). Multiple gene-to-gene interactions in children with sepsis: A combination of five gene variants predicts outcome of life-threatening sepsis. Crit. Care., 18 (1), R1.10.1186/cc13174405644124383711Search in Google Scholar

Kumpf, O., Schumann, R. R. (2008). Genetic influence on bloodstream infections and Sepsis. Int. J. Antimicr. Agents,32, S44–S50.10.1016/j.ijantimicag.2008.08.00218849152Search in Google Scholar

Kuniholm, M. H., Xie, X., Anastos, K., Xue, X., Reimers, L., French, A. L., Gange, S. J., Kassaye, S. G., Kovacs, A., Wang. T., Aouizerat, B. E., Strickler, H. D. (2016). Human leucocyte antigen class I and II imputation in a multiracial population. Int. J. Immunogenet.,43 (6), 369–375.10.1111/iji.12292511815627774761Search in Google Scholar

Landelle, C., Lepape, A., Voirin, N., Tognet, E., Venet, F., Bohé, J., Vanhems, P., Monneret, G. (2010). Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock. Int. Care Med., 36 (11), 1859–1866.10.1007/s00134-010-1962-x20652682Search in Google Scholar

Leentjens, J., Kox, M., van der Hoeven, J.G., Netea, M.G., Pickkers, P. (2013). Immunotherapy for the adjunctive treatment of sepsis: From immunosuppression to immunostimulation. Time for a paradigm change? Amer. J. Respir. Crit. Care Med., 187 (12), 1287–1293.10.1164/rccm.201301-0036CP23590272Search in Google Scholar

Levy, M. M., Dellinger, R. P., Townsend, S. R., Linde-Zwirble, W. T., Marshall, J. C., Bion, J., Schorr, C., Artigas, A., Ramsay, G., Beale, R., Parker, M. M., Gerlach, H., Reinhart, K., Silva, E., Harvey, M., Regan, S., Angus, D. C. (2010). The Surviving Sepsis Campaign: Results of an international guideline-based performance improvement program targeting severe sepsis. Intensive Care Med., 36 (2), 222–231.10.1007/s00134-009-1738-3282663320069275Search in Google Scholar

Mato, A. R., Fuchs, B. D., Heitjan, D. F., Mick, R., Halpern, S. D., Shah, P. D., Jacobs, S., Olson, E., Schuster, S. J., Ujjani, C., Chong, E. A., Loren, A. W., Luger, S. M. (2009). Utility of the systemic inflammatory response syndrome (SIRS) criteria in predicting the onset of septic shock in hospitalized patients with hematologic malignancies. Cancer Biol. Ther., 8 (12), 1095–1100.10.4161/cbt.8.12.852819652524Search in Google Scholar

Michalek, J., Svetlikova, P., Fedora, M., Klimovic, M., Klapacova, L., Bartosova, D., Hrstkova, H., Hubacek, J. A. (2007). Interleukin-6 gene variants and the risk of sepsis development in children. Human Immunol., 68 (9), 756–760.10.1016/j.humimm.2007.06.00317869650Search in Google Scholar

Monneret, G., Venet, F. (2015). Sepsis-induced immune alterations monitoring by flow cytometry as a promising tool for individualized therapy. Cytometry B Clin. Cytom.,90 (4), 376–386.10.1002/cyto.b.21270Search in Google Scholar

Monneret, G., Venet, F., Pachot, A., Lepape, A. (2008). Monitoring immune dysfunctions in the septic patient: A new skin for the old ceremony. Mol. Med., 17, 64–78.10.2119/2007-00102.Monneret207855718026569Search in Google Scholar

Hutchins, N. A., Unsinger, J., Hotchkiss, R. S., Ayala, A. (2014). The new normal: Immuno-modulatory agents against sepsis immune suppression. Trends Mol. Med., 20 (4), 224–233.10.1016/j.molmed.2014.01.002397678524485901Search in Google Scholar

Otto, G. P., Sossdorf, M., Claus, R. A., Rödel, J., Menge, K., Reinhart, K., Bauer, M., Riedemann, N. C. (2011). The late phase of sepsis is characterized by an increased microbiological burden and death rate. Crit. Care., 15 (4), R183.10.1186/cc10332338762621798063Search in Google Scholar

Pachot, A., Monneret, G., Brion, A., Venet, F., Bohé, J., Bienvenu, J., Mougin, B., Lepape, A. (2005). Messenger RNA expression of major histocompatibility complex class II genes in whole blood from septic shock patients. Crit. Care Med.,33 (1), 31–38.10.1097/01.CCM.0000150958.20209.A3Search in Google Scholar

Payen, D., Monneret, G., Hotchkiss, R. (2013). Immunotherapy—a potential new way forward in the treatment of sepsis. Crit. Care,17, 118.10.1186/cc12490405602123425441Search in Google Scholar

Shimokawa, P. T., Targa, L. S., Yamamoto, L., Rodrigues, J. C., Kanunfre, K. A., Okay, T. S. (2016). HLA-DQA1/B1 alleles as putative susceptibility markers in congenital toxoplasmosis. Virulence, 7 (4), 456–464.10.1080/21505594.2016.1150401487167326856406Search in Google Scholar

Watson, R. S., Carcillo, J. A., Linde-Zwirble, W. T., Clermont, G., Lidicker, J., Angus, D. C. (2003). The epidemiology of severe sepsis in children in the United States. Amer. J. Respir. Crit. Care Med., 167, 695–701.10.1164/rccm.200207-682OC12433670Search in Google Scholar