1. |
Durankus et al., 2020 |
Experimental |
48 male Sprague-Dawley rats |
200 mg/kg and 400 mg/kg ibuprofen injection intraperitoneally 30 minutes before disease induction |
Pentylenetetrazole 35 mg/kg intraperitoneally |
Reduced spike percentage in EEG, Racine Convulsion Score and low first myoclonic jerk |
2. |
Peng et al., 2019 |
Experimental |
60 male Sprague-Dawley rats |
30 mg/kg ibuprofen injection intraperitoneally 30 minutes before disease induction |
Pentylenetetrazole 35 mg/kg intraperitoneally |
Reduced, number, grade, latency, shortened duration of seizures and number of small amplitude spikes and spine slow waves in EEG |
3. |
Liu et al., 2020 |
Experimental |
64 male Sprague-Dawley rats |
30 mg/kg ibuprofen injection intraperitoneally 30 minutes before disease nduction |
Pentylenetetrazole 35 mg/kg intraperitoneally |
Reduced frequency, latency and duration of seizures |