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Electrode positioning to investigate the changes of the thoracic bioimpedance caused by aortic dissection – a simulation study

INFORMAZIONI SU QUESTO ARTICOLO

Cita

Fig. 1

a) Intimal tear in the aorta [2]. b) Aortic dissection types (Stanford system) [3].
a) Intimal tear in the aorta [2]. b) Aortic dissection types (Stanford system) [3].

Fig. 2

The spatial average time-dependent cross-sectional radius of the aortic arch and the descending aorta during one cardiac cycle.
The spatial average time-dependent cross-sectional radius of the aortic arch and the descending aorta during one cardiac cycle.

Fig. 3

The spatial average time-dependent blood velocity in the aortic arch and the descending aorta.
The spatial average time-dependent blood velocity in the aortic arch and the descending aorta.

Fig. 4

Orientation and deformation of RBCs in a blood vessel during the systole and diastole.
Orientation and deformation of RBCs in a blood vessel during the systole and diastole.

Fig. 5

The blood conductivity changes as a function of reduced average velocity 〈v/R〉 for different haematocrit (H) levels.
The blood conductivity changes as a function of reduced average velocity 〈v/R〉 for different haematocrit (H) levels.

Fig. 6

Simulation model setup. a) 3D view – b) 2D bottom view.
Simulation model setup. a) 3D view – b) 2D bottom view.

Fig. 7

Flow disturbances around the dissection in case of an aortic dissection.
Flow disturbances around the dissection in case of an aortic dissection.

Fig. 8

Damage factor DF as a function of the radius of the false lumen.
Damage factor DF as a function of the radius of the false lumen.

Fig. 9

Source electrode pairs and measurement electrode pairs positions.
Source electrode pairs and measurement electrode pairs positions.

Fig. 10

Values of 



Y^n,mPCE(t)
\widehat Y_{n,m}^{PCE}(t)


 reflecting the discrepancy between the healthy and dissected conditions for 20-time steps and all proposed electrode combinations.
Values of Y^n,mPCE(t) \widehat Y_{n,m}^{PCE}(t) reflecting the discrepancy between the healthy and dissected conditions for 20-time steps and all proposed electrode combinations.

Fig. 11

Maximal discrepancy 



Y^maxPCE
\widehat Y_{max}^{PCE}


 for the fourth time step and each electrode configuration. Colours show source electrodes; blue: injection from A, red: injection from B, yellow: injection from C; numbers show the measurement electrodes.
Maximal discrepancy Y^maxPCE \widehat Y_{max}^{PCE} for the fourth time step and each electrode configuration. Colours show source electrodes; blue: injection from A, red: injection from B, yellow: injection from C; numbers show the measurement electrodes.

Fig. 12

Sensitivity analysis on a. 



HC^C,4PCE(t)
\widehat {HC}_{C,4}^{PCE}(t)


, b. 



DC^C,4PCE(t)
\widehat {DC}_{C,4}^{PCE}(t)


, c. 



Y^C,4PCE(t)
\widehat Y_{C,4}^{PCE}(t)


.
Sensitivity analysis on a. HC^C,4PCE(t) \widehat {HC}_{C,4}^{PCE}(t) , b. DC^C,4PCE(t) \widehat {DC}_{C,4}^{PCE}(t) , c. Y^C,4PCE(t) \widehat Y_{C,4}^{PCE}(t) .

Fig. 13

Changing of 



Y^maxPCE
\widehat Y_{max}^{PCE}


 by the damage factor for injection from source electrodes C (inj C) and measurement from five electrode pairs (m1 to m5).
Changing of Y^maxPCE \widehat Y_{max}^{PCE} by the damage factor for injection from source electrodes C (inj C) and measurement from five electrode pairs (m1 to m5).

Fig. 14

a. 



HC^C,4PCE(t)
\widehat {HC}_{C,4}^{PCE}(t)


 and 



DC^C,4PCE(t)
\widehat {DC}_{C,4}^{PCE}(t)


 for different damage factors, b. 



Y^C,4PCE(t)
\widehat Y_{C,4}^{PCE}(t)


 for different damage factors.
a. HC^C,4PCE(t) \widehat {HC}_{C,4}^{PCE}(t) and DC^C,4PCE(t) \widehat {DC}_{C,4}^{PCE}(t) for different damage factors, b. Y^C,4PCE(t) \widehat Y_{C,4}^{PCE}(t) for different damage factors.

Input space description for the healthy and dissected study cases.

Cases Variable Distribution Moments Unit
Healthy RTL Uniform [1.35 1.95] cm
θH Uniform [1.0 1.1] -
Dissected RTL Uniform [1.35 1.95] cm
θH Uniform [1.0 1.1] -
RTL Uniform [0.3 1.5] cm
αFL Uniform [2.9 3.65] rad