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Hypercoagulopathy in Overweight and Obese COVID-19 Patients: A Single-Center Case Series

Azza Sarfraz

Azza Sarfraz

  • Larkin Health SystemSouth Miami, FL, USA
  • Pediatrics and Child Health, The Aga Khan UniversityKarachi, Pakistan
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Sarfraz, Azza
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Zouina Sarfraz

Zouina Sarfraz

  • Larkin Health SystemSouth Miami, FL, USA
  • Research and Publications, Fatima Jinnah Medical UniversityLahore, Pakistan
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Sarfraz, Zouina
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Aman Siddiqui

Aman Siddiqui

  • Larkin Health SystemSouth Miami, FL, USA
  • Internal Medicine, Dow University of Health SciencesKarachi, Pakistan
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Siddiqui, Aman
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Ali Totonchian

Ali Totonchian

Internal Medicine, Dow University of Health SciencesKarachi, Pakistan
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Totonchian, Ali
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Syed Hashim Abbas Ali Bokhari

Syed Hashim Abbas Ali Bokhari

School of Medicine, The Aga Khan UniversityKarachi, Pakistan
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Bokhari, Syed Hashim Abbas Ali
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Hafiza Hussain

Hafiza Hussain

Research and Publications, Fatima Jinnah Medical UniversityLahore, Pakistan
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Hussain, Hafiza
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Muzna Sarfraz

Muzna Sarfraz

Larkin Health SystemSouth Miami, FL, USA
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Sarfraz, Muzna
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Gaurav Patel

Gaurav Patel

Larkin Health SystemSouth Miami, FL, USA
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Patel, Gaurav
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Muhammad Hassaan Amjad

Muhammad Hassaan Amjad

Neurosurgery, Sir Ganga Ram HospitalLahore, Pakistan
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Amjad, Muhammad Hassaan
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Sameer Saleem Tebha

Sameer Saleem Tebha

Larkin Health SystemSouth Miami, FL, USA
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Tebha, Sameer Saleem
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Ivan Cherrez-Ojeda

Ivan Cherrez-Ojeda

  • Allergy and Pulmonology, Universidad de Especialidades Espíritu SantoGuayaquil, Ecuador
  • Respiralab Research CenterGuayaquil, Ecuador
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Cherrez-Ojeda, Ivan
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Patrick Dreyer

Patrick Dreyer

Larkin Health SystemSouth Miami, FL, USA
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Dreyer, Patrick
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Harshad Amin

Harshad Amin

Larkin Health SystemSouth Miami, FL, USA
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Amin, Harshad
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Jack Michel

Jack Michel

Larkin Health SystemSouth Miami, FL, USA
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Michel, Jack
  
13 nov 2021
Hypercoagulopathy in Overweight and Obese COVID-19 Patients: A Single-Center Case Series's Cover Image
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Categoria dell'articolo: Case report
Pubblicato online: 13 nov 2021
Pagine: 41 - 48
Ricevuto: 24 apr 2021
Accettato: 07 ago 2021
DOI: https://doi.org/10.2478/jccm-2021-0032
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© 2022 Azza Sarfraz, Zouina Sarfraz, Aman Siddiqui, Ali Totonchian, Syed Hashim Abbas Ali Bokhari, Hafiza Hussain, Muzna Sarfraz, Gaurav Patel, Muhammad Hassaan Amjad, Sameer Saleem Tebha, Ivan Cherrez-Ojeda, Patrick Dreyer, Harshad Amin, Jack Michel, published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

Fig. 1

C.T. Scan: Abdomen and Pelvis without contrast on Day 21 of admission.
C.T. Scan: Abdomen and Pelvis without contrast on Day 21 of admission.

Fig. 2

Significant events of all patients during hospital stay from day 1 of admission.
Significant events of all patients during hospital stay from day 1 of admission.

Demographic, baseline, and laboratory characteristics of patients at hospital admission_

Patient 1 Patient 2 Patient 3 Patient 4 Patient 5
Demographic and baseline characteristics
Age, years 68 62 41 64 96
Gender Male Male Female Female Male
BMI (kg/m2) 31.8 28.2 30.18 35.34 28.74
The severity of COVID-19 at admission Negative Mild Moderate Moderate Mild
Previous illnesses HTN, D.M., and CHF DM Asthma HTN, hypothyroid- ism, breast cancer HTN, COPD, CAD, D.M., HLD
Anti-thrombotic use at baseline
Anticoagulants No No No No Yes
Anti-platelet drugs No No No Yes No
Time from symptom onset to start of treatment (days) 13 days 2 days 14 days 5 days 1 day
Symptoms Exertional dyspnoea and orthopnoea Fever, cough, and fatigue Shortness of breath and pro- ductive cough Shortness of breath and tachypnea Functional decline
Vital signs on Day 1 of admission
Temperature (°F) 98.7 102.4 (fever) 98.6 98.8 97.9
Respiratory rate (breaths per min) 17 20 24 18 20
Oxygen saturation on room air 98% 97% 89% 97% 100%
Blood pressure (mm Hg) 109/77 144/88 96/65 138/66 148/88
Heart rate (beats per min) 95 69 103 76 76
Laboratory findings on Day 1 of admission
White blood cell count (x109 cells per L) 10.95 5.13 6.3 7.98 7.1
Lymphocyte count (109 cells per L) 1.55 1.09 0.6 0.44 0.73
Neutrophil count (109 cells per L) 8.52 3.65 5.4 6.74 5.23
The neutrophil-to-lympho- cyte ratio (NLR) 5.49 3.35 9 15.32 7.16
Haemoglobin (g/L) 9.7 12.5 11.9 13.3 14.9
Platelet count (109 per L) 246 (Mini- 119 (Mini- 301 (Minimum: 212 (Minimum: 82) 238 (Minimum:
mum: 174) mum: 68) 41) 203)
Creatinine (mg/dL) 1.7 1.0 0.8 0.7 1.5
C-reactive protein (mg/dL) 3.4 (Peak: 9.8) 2.7 (Peak: 9) 15.2 (Peak: 16 2.3 (Peak: 16) 7.5 (Peak: 10.44)
ESR (mm/hr) 23 20 78 50 13
LDH (U/L) 174 (Peak: 319 (Peak: 406 (Peak: 261 (Peak: 666) 209 (Peak: 340)
519) 498) 1316.6)
Ferritin (ng/mL) 214.9 (Peak: 234.9 (Peak: 338.1 (Peak: 183.2 (Peak: 218.2) 60 (Peak: 123.5)
455.9) 1506.5) 1506.5)
D-dimer (ng/mL) 268 (Peak: 367 (Peak: 2506 (Peak: 306 (Peak: 878) 708 (Peak: 3480)
4201) 4081) 5199)
Procalcitonin (ng/mL) 0.2 NA 0.2 0.61 0.26
Lingua:
Inglese
Frequenza di pubblicazione:
4 volte all'anno
Argomenti della rivista:
Medicina, Medicina clinica, Medicina interna, Medicina interna, altro, Chirurgia, Chirurgia, altro, Anestesiologia, Medicina d'urgenza e medicina di terapia intensiva
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