Demographic and baseline characteristics |
|
|
|
|
|
Age, years |
68 |
62 |
41 |
64 |
96 |
Gender |
Male |
Male |
Female |
Female |
Male |
BMI (kg/m2) |
31.8 |
28.2 |
30.18 |
35.34 |
28.74 |
The severity of COVID-19 at admission |
Negative |
Mild |
Moderate |
Moderate |
Mild |
Previous illnesses |
HTN, D.M., and CHF |
DM |
Asthma |
HTN, hypothyroid- ism, breast cancer |
HTN, COPD, CAD, D.M., HLD |
|
Anti-thrombotic use at baseline |
|
|
|
|
|
Anticoagulants |
No |
No |
No |
No |
Yes |
Anti-platelet drugs |
No |
No |
No |
Yes |
No |
Time from symptom onset to start of treatment (days) |
13 days |
2 days |
14 days |
5 days |
1 day |
Symptoms |
Exertional dyspnoea and orthopnoea |
Fever, cough, and fatigue |
Shortness of breath and pro- ductive cough |
Shortness of breath and tachypnea |
Functional decline |
|
Vital signs on Day 1 of admission |
|
|
|
|
|
Temperature (°F) |
98.7 |
102.4 (fever) |
98.6 |
98.8 |
97.9 |
Respiratory rate (breaths per min) |
17 |
20 |
24 |
18 |
20 |
Oxygen saturation on room air |
98% |
97% |
89% |
97% |
100% |
Blood pressure (mm Hg) |
109/77 |
144/88 |
96/65 |
138/66 |
148/88 |
Heart rate (beats per min) |
95 |
69 |
103 |
76 |
76 |
|
Laboratory findings on Day 1 of |
admission |
|
|
|
|
White blood cell count (x109 cells per L) |
10.95 |
5.13 |
6.3 |
7.98 |
7.1 |
Lymphocyte count (109 cells per L) |
1.55 |
1.09 |
0.6 |
0.44 |
0.73 |
Neutrophil count (109 cells per L) |
8.52 |
3.65 |
5.4 |
6.74 |
5.23 |
The neutrophil-to-lympho- cyte ratio (NLR) |
5.49 |
3.35 |
9 |
15.32 |
7.16 |
Haemoglobin (g/L) |
9.7 |
12.5 |
11.9 |
13.3 |
14.9 |
Platelet count (109 per L) |
246 (Mini- |
119 (Mini- |
301 (Minimum: |
212 (Minimum: 82) |
238 (Minimum: |
|
mum: 174) |
mum: 68) |
41) |
|
203) |
Creatinine (mg/dL) |
1.7 |
1.0 |
0.8 |
0.7 |
1.5 |
C-reactive protein (mg/dL) |
3.4 (Peak: 9.8) |
2.7 (Peak: 9) |
15.2 (Peak: 16 |
2.3 (Peak: 16) |
7.5 (Peak: 10.44) |
ESR (mm/hr) |
23 |
20 |
78 |
50 |
13 |
LDH (U/L) |
174 (Peak: |
319 (Peak: |
406 (Peak: |
261 (Peak: 666) |
209 (Peak: 340) |
|
519) |
498) |
1316.6) |
|
|
Ferritin (ng/mL) |
214.9 (Peak: |
234.9 (Peak: |
338.1 (Peak: |
183.2 (Peak: 218.2) |
60 (Peak: 123.5) |
|
455.9) |
1506.5) |
1506.5) |
|
|
D-dimer (ng/mL) |
268 (Peak: |
367 (Peak: |
2506 (Peak: |
306 (Peak: 878) |
708 (Peak: 3480) |
|
4201) |
4081) |
5199) |
|
|
Procalcitonin (ng/mL) |
0.2 |
NA |
0.2 |
0.61 |
0.26 |