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Figure 1
NE immunostaining in OSCC. A- No NE immuno-staining (400 × magnification), B- Mild (1–25%) NE immuno-staining (400 × magnification), C- Intense (>50%) NE immuno-staining (400 × magnification).
Study characteristics.
Study groups
Average Age (in years)
Gender
Site
Staging
Male
Female
Gingivo-buccal sulcus
Alveolus
Tongue
Buccal mucosa
III
IV
OSCC with lymph node metastasis
52.92
16
9
8
10
3
4
18
7
OSCC without lymph node metastasis
53.88
17
8
9
11
2
3
19
6
Association between staining intensity and lymph node status.
Staining Intensity
Lymph node status
p-value
N1
N2
N3
Negative
7
0
0
0.001*
Positive, well differentiated
4
4
3
Positive Moderately Differentiated
0
3
4
Association between staining intensity and lymph node involvement.