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Assessing the potential role of neutrophil elastase as a prognostic indicator in oral squamous cell carcinoma

Pooja Jaiswal

Pooja Jaiswal

Department of Oral Pathology and MicrobiologyPimpri, India
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Jaiswal, Pooja
, 
Supriya Kheur

Supriya Kheur

Department of Oral Pathology and MicrobiologyPimpri, India
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Kheur, Supriya
, 
Pratiksha Mahajan

Pratiksha Mahajan

Department of Oral Pathology and MicrobiologyPimpri, India
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Mahajan, Pratiksha
, 
A. Thirumal Raj

A. Thirumal Raj

Department of Oral Pathology and Microbiology, Sri Venkateswara Dental CollegeChennai, India
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Thirumal Raj, A.
, 
Mamatha Reddy

Mamatha Reddy

Department of Oral Pathology and MicrobiologyPimpri, India
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Reddy, Mamatha
, 
Roopa Madalli

Roopa Madalli

Department of Oral Pathology and MicrobiologyPimpri, India
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Madalli, Roopa
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Nitin Gupta

Nitin Gupta

Department of Oral Pathology and MicrobiologyPimpri, India
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Gupta, Nitin
  
05 apr 2020
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Categoria dell'articolo: Research Article
Pubblicato online: 05 apr 2020
Pagine: 34 - 38
Ricevuto: 10 set 2018
Accettato: 25 mar 2019
DOI: https://doi.org/10.2478/fco-2019-0004
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© 2019 Pooja Jaiswal et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Figure 1

NE immunostaining in OSCC. A- No NE immuno-staining (400 × magnification), B- Mild (1–25%) NE immuno-staining (400 × magnification), C- Intense (>50%) NE immuno-staining (400 × magnification).
NE immunostaining in OSCC. A- No NE immuno-staining (400 × magnification), B- Mild (1–25%) NE immuno-staining (400 × magnification), C- Intense (>50%) NE immuno-staining (400 × magnification).

Study characteristics_

Study groupsAverage Age (in years)GenderSiteStaging
MaleFemaleGingivo-buccal sulcusAlveolusTongueBuccal mucosaIIIIV
OSCC with lymph node metastasis52.9216981034187
OSCC without lymph node metastasis53.8817891123196

Association between staining intensity and lymph node status_

Staining IntensityLymph node statusp-value
N1N2N3
Negative7000.001*
Positive, well differentiated443
Positive Moderately Differentiated034

Association between staining intensity and lymph node involvement_

Staining IntensityLymph node involvementp-value
PositiveNegative
Negative7200.0005*
+ Positive122
++ Positive63
+++ Positive00
Lingua:
Inglese
Frequenza di pubblicazione:
2 volte all'anno
Argomenti della rivista:
Medicina, Medicina clinica, Medicina interna, Ematologia, Oncologia
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