<abstract xmlns="http://www.w3.org/1999/xhtml">

<bold>Introduction.</bold> Urinary tract infection (UTI) is one of the most common types of infection in both hospitalized and outpatient settings. The etiology is mostly bacterial, and the typical causative agent is uropathogenic <italic>Escherichia coli</italic>. There is a noticeable increase in drug resistance of pathogenic microorganisms.
<bold>The aim</bold> of the study was retrospective analyses of etiological agents of UTI and their antibiotic resistance patterns in Nephrology Unit patients.
<bold>Material and methods</bold>. An infection was diagnosed based on the patient’s symptoms and positive results of urine culture, carried out over 26 months. The clinical material was tested by using the VITEK system, the drug susceptibility of the emerged pathogens was identified.
<bold>Results.</bold> The most common etiological agents of UTI were Gram-negative rods: <italic>Escherichia coli</italic> (51.23%), <italic>Klebsiella</italic> spp. (19.3%) and <italic>Proteus</italic> spp. (13.68%). The analysis of drug resistance profiles of these pathogens showed a high percentage of strains resistant to broad-spectrum penicillins and fluoroquinolones. At the same time, it seems that <italic>E. coli</italic> isolates presented the most favorable pattern of drug susceptibility in this comparison.
<bold>Conclusions.</bold> The alarming tendency of increasing drug resistance among pathogens causing UTIs to antibiotics such as penicillins or fluoroquinolones prompts a careful choice of drugs in empirical therapies. The most appropriate practice in this regard seems to be meticulous control of nosocomial infections and making therapeutic decisions based on the knowledge of local microbiological data.
</abstract>

Introduction. Urinary tract infection (UTI) is one of the most common types of infection in both hospitalized and outpatient settings. The etiology is mostly bacterial, and the typical causative agent is uropathogenic Escherichia coli. There is a noticeable increase in drug resistance of pathogenic microorganisms.
The aim of the study was retrospective analyses of etiological agents of UTI and their antibiotic resistance patterns in Nephrology Unit patients.
Material and methods. An infection was diagnosed based on the patient’s symptoms and positive results of urine culture, carried out over 26 months. The clinical material was tested by using the VITEK system, the drug susceptibility of the emerged pathogens was identified.
Results. The most common etiological agents of UTI were Gram-negative rods: Escherichia coli (51.23%), Klebsiella spp. (19.3%) and Proteus spp. (13.68%). The analysis of drug resistance profiles of these pathogens showed a high percentage of strains resistant to broad-spectrum penicillins and fluoroquinolones. At the same time, it seems that E. coli isolates presented the most favorable pattern of drug susceptibility in this comparison.
Conclusions. The alarming tendency of increasing drug resistance among pathogens causing UTIs to antibiotics such as penicillins or fluoroquinolones prompts a careful choice of drugs in empirical therapies. The most appropriate practice in this regard seems to be meticulous control of nosocomial infections and making therapeutic decisions based on the knowledge of local microbiological data.

Pathogen profile of urinary tract infections in Nephrology Unit

Chair and Department of Medical Microbiology

Current Issues in Pharmacy and Medical Sciences

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Pathogen profile of urinary tract infections in Nephrology Unit"}

Introduction. Urinary tract infection (UTI) is one of the most common types of infection in both hospitalized and outpatient settings. The etiology is mostly...

Pathogen profile of urinary tract infections in Nephrology Unit

Pubblicato online: 30 dic 2021

Pagine: 201 - 205

Ricevuto: 26 ago 2021

Accettato: 18 ott 2021

DOI: https://doi.org/10.2478/cipms-2021-0036

Parole chiave
nosocomial infection, antibiotic resistance,

© 2021 Dariusz Chojeta et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Pathogen profile of urinary tract infections in Nephrology Unit

Pubblicato online: 30 dic 2021

Pagine: 201 - 205

Ricevuto: 26 ago 2021

Accettato: 18 ott 2021

DOI: https://doi.org/10.2478/cipms-2021-0036

Parole chiavenosocomial infection, antibiotic resistance,

© 2021 Dariusz Chojeta et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
nosocomial infection, antibiotic resistance,