Mutations Detected | Patients ( | % |
---|---|---|
Deletions in exon 19 | 31 | 56.4 |
L858R | 20 | 36.4 |
Insertions in exon 20 | 2 | 3.6 |
Deletions in exon 19 and T790M | 1 | 1.8 |
Deletions in exon 19 and S768I | 1 | 1.8 |
Clinicopathological Features | Total Patients ( | Patients with Mutations or Wild-Type ( | ||
---|---|---|---|---|
Mutations | Wild-Type | |||
Gender: | ||||
males | 407 | 16 | 391 | <0.0001 |
females | 144 | 39 | 105 | |
Histology: | ||||
adenocarcinomas | 276 | 41 | 235 | |
other types | 275 | 14 | 261 | 0.000232 |
Smoking history: | ||||
smokers | 338 | 23 | 315 | |
non smokers | 213 | 32 | 181 | 0.002807 |