Safety Assessment of Locusta migratoria Powder Enriched Peanut-Based Ready-to-Use Therapeutic Foods (RUTF)

1. Akande, O. A., Oluwamukomi, M. O., Osundahunsi, O. F., Ijarotimi, O. S., & Mukisa, I. M. (2022). Evaluating the potential for utilising migratory locust powder (Locusta migratoria) as an alternative protein source in peanut-based ready-to-use therapeutic foods. Food Science and Technology International, 0(0), 1-13.10.1177/1082013221106977335040705 Search in Google Scholar

2. Akhtar, Y., & Isman, M. B. (2018). Insects as an alternative protein source. In Proteins in food processing (pp. 263-288). Woodhead Publishing.10.1016/B978-0-08-100722-8.00011-5 Search in Google Scholar

3. Ali, H., & Khan, E. (2019). Trophic transfer, bioaccumulation, and biomagnification of non-essential hazardous heavy metals and metalloids in food chains/webs—Concepts and implications for wildlife and human health. Human and Ecological Risk Assessment: An International Journal, 25(6), 1353-1376.10.1080/10807039.2018.1469398 Search in Google Scholar

4. Association of Analytical Chemists (AOAC) (2005). Official Methods of Analysis of the Analytical Chemist International, Gaithersburg Md: Washington DC. Search in Google Scholar

5. Association of Analytical Chemists (AOAC) (2006). Official Methods of Analysis of the Analytical Chemist International, Gaithersburg Md: Washington DC. Search in Google Scholar

6. Balkhair, K. S., & Ashraf, M. A. (2016). Field accumulation risks of heavy metals in soil and vegetable crop irrigated with sewage water in western region of Saudi Arabia. Saudi journal of biological sciences, 23(1), S32-S44.10.1016/j.sjbs.2015.09.023470524726858563 Search in Google Scholar

7. Bánfalvi, G. (2011). Heavy metals, trace elements and their cellular effects. In Cellular effects of heavy metals (pp. 3-28). Springer, Dordrecht.10.1007/978-94-007-0428-2_1 Search in Google Scholar

8. Battaglia, M., Cruywagen, C. W., Bertuzzi, T., Gallo, A., Moschini, M., Piva, G., & Masoero, F. (2010). Transfer of melamine from feed to milk and from milk to cheese and whey in lactating dairy cows fed single oral doses. Journal of dairy science, 93(11), 5338-5347.10.3168/jds.2010-332620965350 Search in Google Scholar

9. Belluco, S., Mantovani, A., & Ricci, A. (2018). Edible insects in a food safety perspective. In Edible insects in sustainable food systems (pp. 109-126). Springer, Cham.10.1007/978-3-319-74011-9_7 Search in Google Scholar

10. Benkerroum, N. (2020). Aflatoxins: Producing-molds, structure, health issues and incidence in Southeast Asian and Sub-Saharan African countries. International journal of environmental research and public health, 17(4), 1215.10.3390/ijerph17041215706856632070028 Search in Google Scholar

11. Blair, A., Ritz, B., Wesseling, C., & Freeman, L.B. (2015). Pesticides and human health. Occupational and Environmental Medicine, 0 (0), 1-2.10.1136/oemed-2014-10245425540410 Search in Google Scholar

12. Charlton, A. J., Dickinson, M., Wakefield, M. E., Fitches, E., Kenis, M., Han, R., ... & Smith, R. (2015). Exploring the chemical safety of fly larvae as a source of protein for animal feed. Journal of Insects as Food and Feed, 1(1), 7-16.10.3920/JIFF2014.0020 Search in Google Scholar

13. Clarkson, C., Mirosa, M., & Birch, J. (2018). Potential of Extracted Locusta Migratoria Protein Fractions as Value-Added Ingredients. Insects, 9(20), 1-12.10.3390/insects9010020587228529425143 Search in Google Scholar

14. Codex Alimentarius Commission and Joint FAO/WHO (2010). Report of the fourth session of the Codex Committee on Contaminants in foods, Izmir, Turkey, Food and Agriculture Organization, Rome, 1-63. Search in Google Scholar

15. Codex Alimentarius Standard (1993). CODEX STAN 229-1993, Analysis of Pesticide Residues: Recommended Methods. REV.1-2003 Search in Google Scholar

16. De Paepe, E., Wauters, J., Van Der Borght, M., Claes, J., Huysman, S., Croubels, S., & Vanhaecke, L. (2019). Ultra-high-performance liquid chromatography coupled to quadrupole orbitrap high-resolution mass spectrometry for multi-residue screening of pesticides, (veterinary) drugs and mycotoxins in edible insects. Food chemistry, 293, 187-196.10.1016/j.foodchem.2019.04.08231151600 Search in Google Scholar

17. Ekeanyanwu, C.L., Alisi, C.S., & Ekeanyanwu, R.C. (2020). Levels of Aflatoxin M1 and selected heavy metals (Pb, Cd, Cr, Cu, Zn, Fe, As, and Hg) in the breast milk of lactating mothers in Southeastern, Nigeria. Food Control, 112.10.1016/j.foodcont.2020.107150 Search in Google Scholar

18. Ekong, E. B. (2006). Jaar BG, Weaver VM. Lead-related nephrotoxicity: a review of the epidemiological evidence. Kidney Int, 70, 2074-2084.10.1038/sj.ki.500180917063179 Search in Google Scholar

19. Elagba, H. M. (2015). Determination of nutritive value of the edible migratory locust Locusta migratoria, Linnaeus, 1758 (Orthoptera: Acrididae). Search in Google Scholar

20. European Union (EU) (2012). Amending Regulation (EC) 1881/2006 as regards the maximum levels of the contaminants ochratoxin A, non-dioxin-like PCBs and melamine in foodstuffs. Official Journal of the European Union, 176, 43-45. Search in Google Scholar

21. European Union Commission (EC) (2010). Commission regulation (EU) no 165/2010 of 26 February 2010, amending regulation (EC) no 1881/2006 setting maximum levels for certain contaminants in foodstuffs as regards aflatoxin. Official Journal of the European Union, L 50, 8-12. Search in Google Scholar

22. FAO/WHO (2017). Proposed Draft Guidelines For Ready-To-Use Therapeutic Foods. Joint FAO/WHO Food Standards Programme Codex Committee on Nutrition and Foods for Special Dietary Uses, 39^th Session, Berlin, Germany, 1-51. Search in Google Scholar

23. Finke, M. D. (2007). Estimate of chitin in raw whole insects. Zoo Biology: Published in affiliation with the American Zoo and Aquarium Association, 26(2), 105-115.10.1002/zoo.2012319360565 Search in Google Scholar

24. Gong, Y. Y., Turner, P. C., Hall, A. J., & Wild, C. P. (2008). Aflatoxin exposure and impaired child growth in West Africa: an unexplored international public health burden. Mycotoxins: detection methods, management, public health and agricultural trade, 53-65.10.1079/9781845930820.0053 Search in Google Scholar

25. IARC Working Group on the Evaluation of Carcinogenic Risks to Humans, & International Agency for Research on Cancer. (2002). Some traditional herbal medicines, some mycotoxins, naphthalene and styrene (Vol. 82). World Health Organization. Search in Google Scholar

26. Ibánez, M., Sancho, J. V., & Hernández, F. (2009). Determination of melamine in milk-based products and other food and beverage products by ion-pair liquid chromatography–tandem mass spectrometry. Analytica chimica acta, 649(1), 91-97.10.1016/j.aca.2009.07.01619664467 Search in Google Scholar

27. Imathiu, S. (2020). Benefits and food safety concerns associated with consumption of edible insects. NFS Journal, 18, 1-11.10.1016/j.nfs.2019.11.002 Search in Google Scholar

28. Jalili, M., & Murshid, M. (2017). A review paper on melamine in milk and dairy products. Journal of Dairy & Veterinary, 1-4.10.19080/JDVS.2017.01.555566 Search in Google Scholar

29. Jawaid, S., Talpur, F. N., Nizamani, S. M., Khaskheli, A. A., & Afridi, H. I. (2016). Multipesticide residue levels in UHT and raw milk samples by GC-μECD after QuEChER extraction method. Environmental monitoring and assessment, 188(4), 230.10.1007/s10661-016-5222-626992902 Search in Google Scholar

30. Kachapulula, P. W., Akello, J., Bandyopadhyay, R., & Cotty, P. J. (2018). Aflatoxin contamination of dried insects and fish in Zambia. Journal of Food Protection, 81(9), 1508-1518.10.4315/0362-028X.JFP-17-52730118348 Search in Google Scholar

31. Khan, A., Khan, S., Khan, M. A., Qamar, Z., & Waqas, M. (2015). The uptake and bioaccumulation of heavy metals by food plants, their effects on plants nutrients, and associated health risk: a review. Environmental Science and Pollution Research, 22(18), 13772-13799.10.1007/s11356-015-4881-026194234 Search in Google Scholar

32. Khlangwiset, P., Shephard, G. S., & Wu, F. (2011). Aflatoxins and growth impairment: a review. Critical reviews in toxicology, 41(9), 740-755.10.3109/10408444.2011.57576621711088 Search in Google Scholar

33. Klunder, H. C., Wolkers-Rooijackers, J., Korpela, J. M., & Nout, M. R. (2012). Microbiological aspects of processing and storage of edible insects. Food control, 26(2), 628-631.10.1016/j.foodcont.2012.02.013 Search in Google Scholar

34. Kolakowski, B.M., Johaniuk, K., Zhang, H., & Yamamoto, E. (2021). Analysis of Microbiological and Chemical Hazards in Edible Insects Available to Canadian Consumers. Journal of Food Protection, 84(9), 1575-1581.10.4315/JFP-21-09933956957 Search in Google Scholar

35. Lam, C. W., Lan, L., Che, X., Tam, S., Wong, S. S. Y., Chen, Y., ... & Tam, P. K. H. (2009). Diagnosis and spectrum of melamine-related renal disease: plausible mechanism of stone formation in humans. Clinica Chimica Acta, 402(1-2), 150-155.10.1016/j.cca.2008.12.03519171128 Search in Google Scholar

36. Le, T., Yan, P., Xu, J., & Hao, Y. (2013). A novel colloidal gold-based lateral flow immunoassay for rapid simultaneous detection of cyromazine and melamine in foods of animal origin. Food chemistry, 138(2-3), 1610-1615.10.1016/j.foodchem.2012.11.07723411288 Search in Google Scholar

37. Lehotay, S.J. (2007). Pesticide Residues in Foods by Acetonitrile Extraction and Partitioning with Magnesium Sulfate. Journal of AOAC International, 90(2), 485-520.10.1093/jaoac/90.2.485 Search in Google Scholar

38. Li, F. Q., Li, Y. W., Wang, Y. R., & Luo, X. Y. (2009). Natural occurrence of aflatoxins in Chinese peanut butter and sesame paste. Journal of agricultural and food chemistry, 57(9), 3519-3524.10.1021/jf804055n19338351 Search in Google Scholar

39. Lutter, P., Savoy-Perroud, M. C., Campos-Gimenez, E., Meyer, L., Goldmann, T., Bertholet, M. C., ... & Delatour, T. (2011). Screening and confirmatory methods for the determination of melamine in cow’s milk and milk-based powdered infant formula: Validation and proficiency-tests of ELISA, HPLC-UV, GC-MS and LC-MS/MS. Food Control, 22(6), 903-913.10.1016/j.foodcont.2010.11.022 Search in Google Scholar

40. Magoha, H., Kimanya, M., De Meulenaer, B., Roberfroid, D., Lachat, C., & Kolsteren, P. (2016). Risk of dietary exposure to aflatoxins and fumonisins in infants less than 6 months of age in R ombo, N orthern T anzania. Maternal & child nutrition, 12(3), 516-527.10.1111/mcn.12155686009325422038 Search in Google Scholar

41. Matumba, L., Monjerezi, M., Biswick, T., Mwatseteza, J., Makumba, W., Kamangira, D., & Mtukuso, A. (2014). A survey of the incidence and level of aflatoxin contamination in a range of locally and imported processed foods on Malawian retail market. Food control, 39, 87-91.10.1016/j.foodcont.2013.09.068 Search in Google Scholar

42. Medecins Sans Frontieres/United Children’s Emergency Fund (MSF/UNICEF) (2013). Ready-to-Use-Therapeutic Food, Product Specification. Retrieved March 1, 2019, from http://www.unicef.org/supply/file/Odile_Caron_RUTF_Product_Specification. Search in Google Scholar

43. Mupunga, I., Mngqawa, P., & Katerere, D. R. (2017). Peanuts, aflatoxins and undernutrition in children in Sub-Saharan Africa. Nutrients, 9(12), 1287.10.3390/nu9121287574873829186859 Search in Google Scholar

44. Musundire, R., Zvidzai, C. J., Chidewe, C., Ngadze, R. T., Macheka, L., Manditsera, F. A., ... & Masheka, A. (2016). Nutritional and bioactive compounds composition of Eulepida mashona, an edible beetle in Zimbabwe. Journal of Insects as Food and Feed, 2(3), 179-187.10.3920/JIFF2015.0050 Search in Google Scholar

45. Nanita, S. C., Stry, J. J., Pentz, A. M., McClory, J. P., & May, J. H. (2011). Fast extraction and dilution flow injection mass spectrometry method for quantitative chemical residue screening in food. Journal of agricultural and food chemistry, 59(14), 7557-7568.10.1021/jf104237y21388127 Search in Google Scholar

46. Oancea, S., and Stoia, M. (2008). Mycotoxins: A review of toxicology, analytical methods and health risks. Acta Universitatis Cibiniensis Series E: FOOD TECHNOLOGY, XII(1), 19-36. Search in Google Scholar

47. Olutona, G. O., & Aderemi, M. A. (2019). Organochlorine pesticide residue and heavy metals in leguminous food crops from selected markets in Ibadan, Nigeria. Legume Science, 1(1), e3.10.1002/leg3.3 Search in Google Scholar

48. Oonincx, D. G., Van Itterbeeck, J., Heetkamp, M. J., Van Den Brand, H., Van Loon, J. J., & Van Huis, A. (2010). An exploration on greenhouse gas and ammonia production by insect species suitable for animal or human consumption. PloS one, 5(12), e14445.10.1371/journal.pone.0014445301205221206900 Search in Google Scholar

49. Özcan, M., & Seven, S. (2003). Physıcal and chemıcal analysıs and fatty acıd composıtıon of peanut, peanut oıl and peanut butter from ÇOM and NC-7 cultıvars. Grasas y aceites, 54(1), 12-18.10.3989/gya.2003.v54.i1.270 Search in Google Scholar

50. Poma, G., Cuykx, M., Amato, E., Calaprice, C., Focant, J. F., & Covaci, A. (2017). Evaluation of hazardous chemicals in edible insects and insect-based food intended for human consumption. Food and Chemical Toxicology, 100, 70-79.10.1016/j.fct.2016.12.00628007452 Search in Google Scholar

51. Purschke, B., Scheibelberger, R., Axmann, S., Adler, A., & Jäger, H. (2017). Impact of substrate contamination with mycotoxins, heavy metals and pesticides on the growth performance and composition of black soldier fly larvae (Hermetia illucens) for use in the feed and food value chain. Food Additives & Contaminants: Part A, 34(8), 1410-1420.10.1080/19440049.2017.129994628278126 Search in Google Scholar

52. Rumpold, B. A., & Schlüter, O. K. (2013). Potential and challenges of insects as an innovative source for food and feed production. Innovative Food Science & Emerging Technologies, 17, 1-11.10.1016/j.ifset.2012.11.005 Search in Google Scholar

53. Saaed, T., Dagga, T.A., & Saraf. M. (1993). Analysis of residual pesticides in edible locusts captured in Kuwait. Arab Gulf Journal of Scientific Research, 11:1–5. Search in Google Scholar

54. Sanabria, C. O., Hogan, N. S., Madder, K. M., & Buchanan, F. C. (2017). 072 Insect larvae fed mycotoxin-contaminated wheat–A possible safe, sustainable protein source for animal feed?. Journal of Animal Science, 95(suppl_4), 36-36.10.2527/asasann.2017.072 Search in Google Scholar

55. Sapbamrer, R., & Hongsibsong, S. (2014). Organophosphorus Pesticide Residues in Vegetables from Farms, Markets, and a Supermarket around Kwan Phayao Lake of Northern Thailand. Archives of Environmental Contamination and Toxicology, DOI 10.1007/s00244-014-0014-x.24609615 Apri DOISearch in Google Scholar

56. Tao, L., Yan, P., Xu, J., & Hao, Y. (2013). A novel colloidal gold-based lateral flow immunoassay for rapid simultaneous detection of cyromazine and melamine in foods of animal origin. Food chemistry, 138(2-3), 1610-1615.10.1016/j.foodchem.2012.11.077 Search in Google Scholar

57. Tola, M., & Kebede, B. (2016). Occurrence, importance and control of mycotoxins: A review. Cogent Food & Agriculture, 2(1), 1191103.10.1080/23311932.2016.1191103 Search in Google Scholar

58. Van Broekhoven, S., Bastiaan-Net, S., de Jong, N. W., & Wichers, H. J. (2016). Influence of processing and in vitro digestion on the allergic cross-reactivity of three mealworm species. Food chemistry, 196, 1075-1083.10.1016/j.foodchem.2015.10.03326593591 Search in Google Scholar

59. Van der Fels-Klerx, H. J., Camenzuli, L., Belluco, S., Meijer, N., & Ricci, A. (2018). Food safety issues related to uses of insects for feeds and foods. Comprehensive Reviews in Food Science and Food Safety, 17(5), 1172-1183.10.1111/1541-4337.1238533350154 Search in Google Scholar

60. Van Huis, A., Van Itterbeeck, J., Klunder, H., Mertens, E., Halloran, A., Muir, G., & Vantomme, P. (2013). Edible insects: future prospects for food and feed security (No. 171). Food and Agriculture Organization of the United Nations. Search in Google Scholar

61. Wanjeri, V. W., Gbashi, S., Ngila, J. C., Njobeh, P., Mamo, M. A., & Ndungu, P. G. (2019). Chemical Vapour Deposition of MWCNT on Silica Coated Fe3O4 and Use of Response Surface Methodology for Optimizing the Extraction of Organophosphorus Pesticides from Water. International journal of analytical chemistry, 2019.10.1155/2019/4564709663653131354825 Search in Google Scholar

62. World Health Organisation. (2008). Melamine and Cyanuric acid: Toxicity, Preliminary Risk Assessment and Guidance on Levels in Food, 1-7. Search in Google Scholar

63. World Vision/United Children’s Emergency Fund (2014). Guidelines for the Selection and Use of New Ready-to-use-Therapeutic Food (RUTF) Products in World Vision Programmes. Healthy children for a healthy world, 1-29. Search in Google Scholar

64. Wuana, R.A. and Okieimen, F.E. (2011). Heavy Metals in Contaminated Soils: A Review of Sources, Chemistry, Risks and Best Available Strategies for Remediation. ISRN Ecology, 1 – 20.10.5402/2011/402647 Search in Google Scholar

65. Xie, J., Liu, T., Song, G., Hu, Y., & Deng, C. (2013). Simultaneous analysis of organophosphorus pesticides in water by magnetic solid-phase extraction coupled with GC–MS. Chromatographia, 76(9-10), 535-540.10.1007/s10337-013-2408-8 Search in Google Scholar

66. Zhang, Z. S., Lu, X. G., Wang, Q. C., & Zheng, D. M. (2009). Mercury, cadmium and lead biogeochemistry in the soil–plant–insect system in Huludao City. Bulletin of environmental contamination and toxicology, 83(2), 255-259.10.1007/s00128-009-9688-6269380319280090 Search in Google Scholar

67. Zielińska, E., Karaś, M., & Jakubczyk, A. (2017). Antioxidant activity of predigested protein obtained from a range of farmed edible insects. International Journal of Food Science & Technology, 52(2), 306-312.10.1111/ijfs.13282 Search in Google Scholar

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