<abstract xmlns="http://www.w3.org/1999/xhtml">

<italic>Objective:</italic> The aim of this prospective study was to evaluate the re-colonisation pattern of <italic>Streptococcus mutans</italic> (MS) in high-level MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement.
<italic>Materials and methods:</italic> The subjects of this single-blinded clinical trial were 13-14-year-old adolescents (N = 14) with significant orthodontic treatment need, a high salivary MS count but without any carious lesions. Baseline MS levels were determined by the cultivation of saliva collected from each subject using strips developed for this purpose (Strip-mutans, Orion Diagnostica, Espoo, Finland). Prior to the bonding of orthodontic brackets, 40% chlorhexidine varnish (EC 40, Explore, Nijmegen, Netherlands) was applied to all teeth for 10 minutes. The re-colonisation of MS was assessed at one, two, four and six week time periods. The data obtained were subjected to a repeated measures design.
<italic>Results</italic>: Chlorhexidine varnish reduced salivary MS significantly at the first, second and fourth weeks compared to baseline values. Significant MS suppression lasted less than six weeks and MS colonisation gradually returned to baseline level.
<italic>Conclusion:</italic> Repeated application of chlorhexidine varnish in orthodontic patients with high MS levels may be beneficial throughout fixed appliance orthodontic treatment.
</abstract>

Objective: The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in high-level MS-colonised patients with fixed orthodontic appliances following 40% chlorhexidine varnish application prior to bracket placement.
Materials and methods: The subjects of this single-blinded clinical trial were 13-14-year-old adolescents (N = 14) with significant orthodontic treatment need, a high salivary MS count but without any carious lesions. Baseline MS levels were determined by the cultivation of saliva collected from each subject using strips developed for this purpose (Strip-mutans, Orion Diagnostica, Espoo, Finland). Prior to the bonding of orthodontic brackets, 40% chlorhexidine varnish (EC 40, Explore, Nijmegen, Netherlands) was applied to all teeth for 10 minutes. The re-colonisation of MS was assessed at one, two, four and six week time periods. The data obtained were subjected to a repeated measures design.
Results: Chlorhexidine varnish reduced salivary MS significantly at the first, second and fourth weeks compared to baseline values. Significant MS suppression lasted less than six weeks and MS colonisation gradually returned to baseline level.
Conclusion: Repeated application of chlorhexidine varnish in orthodontic patients with high MS levels may be beneficial throughout fixed appliance orthodontic treatment.

Effect of chlorhexidine varnish application on <italic>Streptococcus mutans</italic> colonisation in adolescents with fixed orthodontic appliances

Department of Orthodontics, School of Dentistry

Department of Pedodontics, School of Dentistry

Australasian Orthodontic Journal

This work is licensed under the Creative Commons Attribution 4.0 International License.

Effect of chlorhexidine varnish application on  colonisation in adolescents with fixed orthodontic appliances

Objective: The aim of this prospective study was to evaluate the re-colonisation pattern of Streptococcus mutans (MS) in high-level MS-colonised patients with...

Effect of chlorhexidine varnish application on Streptococcus mutans colonisation in adolescents with fixed orthodontic appliances

Pubblicato online: 01 ago 2023

Pagine: 52 - 57

Ricevuto: 01 giu 2012

Accettato: 01 feb 2013

DOI: https://doi.org/10.2478/aoj-2013-0008

© 2013 Rengin Attin et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.