<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Taste disorders are a serious impediment to the process of eating meals. There are many mechanisms that determine the development of taste disorders. One of them is believed to be zinc deficiency. Zinc is responsible for the processes of regeneration of taste and smell centres. It plays a significant role in the cells of the taste bud. Our study aims to present the role of zinc deficiency on the occurrence of taste disorders in selected medical aspects, such as in the course of diabetes, as a result of radiotherapy and chemotherapy of head and neck cancers, resulting from old age, and in the course of oral cavity halitosis. The study analyzed articles available in the PubMed database. The consequence of the reduced zinc content is its incorrect amount in the epithelium of the tongue, which may be the result of a reduced ability of cells to regenerate after the destructive effects of pathological factors. The result of zinc deficiency is its reduced amount in the salivary glands, which results in reduced activity of carbonic anhydrase 6 (gustin), which is a component of saliva. Zinc is also involved in the process of experiencing taste by affecting neuronal processes. Zinc ions inhibit oral malodor by binding directly to hydrogen sulfide gas and by inhibiting the growth of oral bacteria that produce volatile sulfur compounds. In the study, we focus on the mechanisms that determine the abnormal perception of taste and potential therapeutic possibilities based on current scientific reports.</p>
</abstract>

Taste disorders are a serious impediment to the process of eating meals. There are many mechanisms that determine the development of taste disorders. One of them is believed to be zinc deficiency. Zinc is responsible for the processes of regeneration of taste and smell centres. It plays a significant role in the cells of the taste bud. Our study aims to present the role of zinc deficiency on the occurrence of taste disorders in selected medical aspects, such as in the course of diabetes, as a result of radiotherapy and chemotherapy of head and neck cancers, resulting from old age, and in the course of oral cavity halitosis. The study analyzed articles available in the PubMed database. The consequence of the reduced zinc content is its incorrect amount in the epithelium of the tongue, which may be the result of a reduced ability of cells to regenerate after the destructive effects of pathological factors. The result of zinc deficiency is its reduced amount in the salivary glands, which results in reduced activity of carbonic anhydrase 6 (gustin), which is a component of saliva. Zinc is also involved in the process of experiencing taste by affecting neuronal processes. Zinc ions inhibit oral malodor by binding directly to hydrogen sulfide gas and by inhibiting the growth of oral bacteria that produce volatile sulfur compounds. In the study, we focus on the mechanisms that determine the abnormal perception of taste and potential therapeutic possibilities based on current scientific reports.

The influence of zinc deficiency on taste disorders in selected medical aspects

aleksandra.kedziora-ciechanska@student.umlub.pl

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"The influence of zinc deficiency on taste disorders in selected medical aspects"}

Taste disorders are a serious impediment to the process of eating meals. There are many mechanisms that determine the development of taste disorders. One of...

Disease	Local: tooth decay, periodontal disease, candidosis, erythema migrans, fissure tongue, glossitis, dermatoses, denture defects
	Systemic diseases: stroke, Alzheimer's disease, Parkinson's disease, depression, diabetes mellitus types 1 and type 2, hypothyroidism/hyperthyroidism, chronic kidney disease, acute and chronic liver disease, cirrhosis, Sjögren's syndrome, irritable bowel syndrome, gastroesophageal reflux disease, hiatus hernia, inflammatory bowel diseases, AIDS

Physiological	atrophy of the oral epithelium, increased degrees of atrophy and fibrosis of the salivary glands, reduction of taste buds

Nutritional deficiencies	Deficiencies of: iron, folic acid, vitamin B12, zinc

Iatrogenic	medicines, chemotherapy, radiotherapy

Allergies	food and additives allergy

The influence of zinc deficiency on taste disorders in selected medical aspects

Article Category: Review

Pubblicato online: 31 dic 2023

Pagine: 188 - 193

Ricevuto: 27 apr 2023

Accettato: 20 nov 2023

DOI: https://doi.org/10.2478/ahem-2023-0025

Parole chiave
taste disorders, zinc, diabetes, radiotherapy, chemotherapy, elderly age, halitosis

© 2023 Aleksandra Kędziora-Ciechańska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Main causes of dysgeusia [11]

The influence of zinc deficiency on taste disorders in selected medical aspects

Article Category: Review

Pubblicato online: 31 dic 2023

Pagine: 188 - 193

Ricevuto: 27 apr 2023

Accettato: 20 nov 2023

DOI: https://doi.org/10.2478/ahem-2023-0025

Parole chiavetaste disorders, zinc, diabetes, radiotherapy, chemotherapy, elderly age, halitosis

© 2023 Aleksandra Kędziora-Ciechańska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Main causes of dysgeusia [11]

Parole chiave
taste disorders, zinc, diabetes, radiotherapy, chemotherapy, elderly age, halitosis