<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Oral cancers, excluding non-melanoma skin cancer, are the most common cancers of the head and neck. Of these, 90% are squamous cell carcinomas (SCC). Surgery, which consists of dissection of the primary tumor and lymphadenectomy, is considered a radical method of treatment. There are several ranges of cervical lymphadenectomy: selective neck dissection (SND), modified radical neck dissection (MRND), and radical neck dissection (RND). The extension of surgery depends on the stage of clinical advancement, which can be determined by TNM classification, among other methods. The greatest controversy is related to SND in patients with cN0 (no evidence of regional lymph node metastasis), which is currently standard procedure. This approach is dictated by the possibility of hidden or subclinical metastases. The use of the sentinel lymph node (SLN) concept in patients with early stage of oral cancer and appropriate methods of its mapping may lead to a reduction in the extent of the lymphadenectomy procedure, thus reducing postoperative mortality and maintaining the patient’s function and quality of life, with correct oncological results. So far, available methods for SLN mapping are based on use of markers: methylene blue dye (MBD), metastable radioactive isotope Technetium (99mTc), or the fluorescent substance indocyanine green (ICG).</p>
</abstract>

Oral cancers, excluding non-melanoma skin cancer, are the most common cancers of the head and neck. Of these, 90% are squamous cell carcinomas (SCC). Surgery, which consists of dissection of the primary tumor and lymphadenectomy, is considered a radical method of treatment. There are several ranges of cervical lymphadenectomy: selective neck dissection (SND), modified radical neck dissection (MRND), and radical neck dissection (RND). The extension of surgery depends on the stage of clinical advancement, which can be determined by TNM classification, among other methods. The greatest controversy is related to SND in patients with cN0 (no evidence of regional lymph node metastasis), which is currently standard procedure. This approach is dictated by the possibility of hidden or subclinical metastases. The use of the sentinel lymph node (SLN) concept in patients with early stage of oral cancer and appropriate methods of its mapping may lead to a reduction in the extent of the lymphadenectomy procedure, thus reducing postoperative mortality and maintaining the patient’s function and quality of life, with correct oncological results. So far, available methods for SLN mapping are based on use of markers: methylene blue dye (MBD), metastable radioactive isotope Technetium (99mTc), or the fluorescent substance indocyanine green (ICG).

Methods for sentinel lymph node mapping in oral cancer: a literature review

Department of Cranio-Maxillo-Facial Surgery

Medical University of Silesia in Katowice

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

{"article-title":"Methods for sentinel lymph node mapping in oral cancer: a literature review"}

Oral cancers, excluding non-melanoma skin cancer, are the most common cancers of the head and neck. Of these, 90% are squamous cell carcinomas (SCC). Surgery,...

Methods for sentinel lymph node mapping in oral cancer: a literature review

Article Category: Review

Pubblicato online: 29 giu 2022

Pagine: 268 - 274

Ricevuto: 16 set 2021

Accettato: 21 gen 2022

DOI: https://doi.org/10.2478/ahem-2022-0029

Parole chiave
sentinel lymph node, head and neck cancer, lymphadenectomy

© 2022 Barbara Trepka-Sirek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Methods for sentinel lymph node mapping in oral cancer: a literature review

Article Category: Review

Pubblicato online: 29 giu 2022

Pagine: 268 - 274

Ricevuto: 16 set 2021

Accettato: 21 gen 2022

DOI: https://doi.org/10.2478/ahem-2022-0029

Parole chiavesentinel lymph node, head and neck cancer, lymphadenectomy

© 2022 Barbara Trepka-Sirek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
sentinel lymph node, head and neck cancer, lymphadenectomy