Salivary HPV infection in healthy people
Małgorzata Radwan-Oczko
Profilo Orcid, Joanna Owczarek-Drabińska
Profilo Orcid, Anna Szczygielska
Profilo Orcid, Marta Szczepaniak
Profilo Orcid e Irena Duś-Ilnicka
Profilo Orcid 
Categoria dell'articolo: Original Study
Pubblicato online: 29 mag 2022
Pagine: 143 - 148
Ricevuto: 30 dic 2020
Accettato: 11 ago 2021
DOI: https://doi.org/10.2478/ahem-2022-0016
Parole chiave
© 2022 Małgorzata Radwan-Oczko et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Introduction
In recent years, interest in human papillomavirus infections as a causative factor in epithelial cancer development has grown. Literature indicates that HPV involvement in malignant transformations in oral mucosa can vary significantly, from 0 up to 87%. The aim of our study was to detect the prevalence of salivary HPV infection among generally healthy adults.
Materials and Methods
The examination involved 139 patients, from whom 139 whole, 1.5ml saliva samples were obtained. HPV DNA was detected by the nested PCR technique. To visualize the PCR products electrophoresis reactions were carried out.
Results
Sample analysis showed that DNA for HPV was detected in 14 patients: 11 positive results were obtained from men, and 3 from women. This yields a high infection rate: 10.07%.
Conclusions
The HPV prevalence in the male group was more than twice as high as in the female group. Also, subclinical oral HPV infection was detected more frequently in young (19–39 years old) and older (=>60 years old) adults.