<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Introduction</h3>
<p>The aim of the paper was to demonstrate that brush cytology can be useful in diagnostic evaluation of precancerous states and laryngeal cancer.</p>
</sec>
<sec><h3>Materials and Methods</h3>
<p>Ninety-two patients were analyzed. The control group included patients with benign laryngeal lesions, while the study group was composed of patients in whom a precancerous condition or laryngeal cancer was suspected. Material for histopathological and cytological examination was collected during a laryngeal microsurgery. The authors analyzed the consistency of the results of cytological and histopathological examination in the diagnostic evaluation of precancerous conditions and laryngeal cancer.</p>
</sec>
<sec><h3>Results</h3>
<p>Comparing diagnoses based on cytological examination with the results of histopathological examinations, the authors observed that there was a strong and statistically significant (<italic>p</italic>&lt;0.001) correlation between the results. The accuracy of brush cytology in the conducted study indicates that the sensitivity and specificity of the test reaches 90.09% and 93.5% with 4 false negative and 3 false positive results. Positive prediction reached 93% and negative prediction reached 91.5%.</p>
</sec>
<sec><h3>Conclusions</h3>
<p>Brush cytology of the larynx may be useful in screening and as an auxiliary test in diagnostic evaluation of precancerous conditions and laryngeal cancer.</p>
</sec>
</abstract>

Introduction
The aim of the paper was to demonstrate that brush cytology can be useful in diagnostic evaluation of precancerous states and laryngeal cancer.

Materials and Methods
Ninety-two patients were analyzed. The control group included patients with benign laryngeal lesions, while the study group was composed of patients in whom a precancerous condition or laryngeal cancer was suspected. Material for histopathological and cytological examination was collected during a laryngeal microsurgery. The authors analyzed the consistency of the results of cytological and histopathological examination in the diagnostic evaluation of precancerous conditions and laryngeal cancer.

Results
Comparing diagnoses based on cytological examination with the results of histopathological examinations, the authors observed that there was a strong and statistically significant (p<0.001) correlation between the results. The accuracy of brush cytology in the conducted study indicates that the sensitivity and specificity of the test reaches 90.09% and 93.5% with 4 false negative and 3 false positive results. Positive prediction reached 93% and negative prediction reached 91.5%.

Conclusions
Brush cytology of the larynx may be useful in screening and as an auxiliary test in diagnostic evaluation of precancerous conditions and laryngeal cancer.

Correlation between brush cytology results and histopathological examination in diagnostic evaluation of precancerous conditions and laryngeal cancer: A prospective study

Clinic of Otolaryngology Head and Neck Surgery

Department and Clinic of Otolaryngology Head and Neck Surgery

Division of Surgical Oncology, Gynecological Oncology, Chemotherapy and Department of Oncology

Department of Pathomorphology and Oncological Cytology

Wroclaw Medical University, Head of the Department

Postępy Higieny i Medycyny Doświadczalnej

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Introduction
The aim of the paper was to demonstrate that brush cytology can be useful in diagnostic evaluation of precancerous states and laryngeal...

Correlation between brush cytology results and histopathological examination in diagnostic evaluation of precancerous conditions and laryngeal cancer: A prospective study

Article Category: Original Study

Pubblicato online: 10 mag 2022

Pagine: 149 - 156

Ricevuto: 09 set 2021

Accettato: 03 feb 2022

DOI: https://doi.org/10.2478/ahem-2022-0015

Parole chiave
brush cytology, histopathological examination, dysplasia, laryngeal squamous carcinoma, screening

© 2022 Paulina Lepka et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Correlation between brush cytology results and histopathological examination in diagnostic evaluation of precancerous conditions and laryngeal cancer: A prospective study

Article Category: Original Study

Pubblicato online: 10 mag 2022

Pagine: 149 - 156

Ricevuto: 09 set 2021

Accettato: 03 feb 2022

DOI: https://doi.org/10.2478/ahem-2022-0015

Parole chiavebrush cytology, histopathological examination, dysplasia, laryngeal squamous carcinoma, screening

© 2022 Paulina Lepka et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Parole chiave
brush cytology, histopathological examination, dysplasia, laryngeal squamous carcinoma, screening