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A Multiple Unit Abuse-deterrent Dosage Form Based on Sodium Alginate

M. Papadakos

M. Papadakos

Comenius University Bratislava, Faculty of Pharmacy, Department of Galenic PharmacyBratislava, Slovakia
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Papadakos, M.
, 
M. Špaglová

M. Špaglová

Comenius University Bratislava, Faculty of Pharmacy, Department of Galenic PharmacyBratislava, Slovakia
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Špaglová, M.
, 
M. Čuchorová

M. Čuchorová

Comenius University Bratislava, Faculty of Pharmacy, Department of Galenic PharmacyBratislava, Slovakia
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Čuchorová, M.
 e 
M. Hanko

M. Hanko

Comenius University Bratislava, Faculty of Pharmacy, Department of Pharmaceutical Analysis and Nuclear PharmacyBratislava, Slovakia
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Hanko, M.
  
15 set 2023
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Categoria dell'articolo: Special issue article
Pubblicato online: 15 set 2023
Pagine: 75 - 79
Ricevuto: 14 apr 2018
Accettato: 01 giu 2018
DOI: https://doi.org/10.2478/afpuc-2023-0020
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© 2023 M. Papadakos et al., published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Figure 1.

Hot dried Ca2+-alginate microcapsules at 77× and 100× magnification.
Hot dried Ca2+-alginate microcapsules at 77× and 100× magnification.

Figure 2.

Ca2+-alginate microcapsules taken after 24 h in artificial intestinal fluid pH 6.8 (a1 – hot dried, a2 – freeze-dried), artificial gastric fluid pH 1.2 (b1 – hot dried, b2 – freeze-dried), and artificial gastric fluid with ethanol 40% (w/w) (c1 – hot dried, c2 – freeze-dried)
Ca2+-alginate microcapsules taken after 24 h in artificial intestinal fluid pH 6.8 (a1 – hot dried, a2 – freeze-dried), artificial gastric fluid pH 1.2 (b1 – hot dried, b2 – freeze-dried), and artificial gastric fluid with ethanol 40% (w/w) (c1 – hot dried, c2 – freeze-dried)

Figure 3.

The swelling ability of Ca2+-alginate microcapsules in artificial gastric fluid (pH 1.2), artificial gastric fluid with 40% (w/w) ethanol (pH 1.2 + EtOH), and artificial intestinal fluid (pH 6.8).
The swelling ability of Ca2+-alginate microcapsules in artificial gastric fluid (pH 1.2), artificial gastric fluid with 40% (w/w) ethanol (pH 1.2 + EtOH), and artificial intestinal fluid (pH 6.8).
Lingua:
Inglese
Frequenza di pubblicazione:
2 volte all'anno
Argomenti della rivista:
Farmacia, Farmacia, altro
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