1. bookVolume 15 (2022): Edizione 1 (January 2022)
Dettagli della rivista
Prima pubblicazione
10 Dec 2012
Frequenza di pubblicazione
2 volte all'anno
access type Accesso libero

Ceylon cinnamon and clove essential oils as promising free radical scavengers for skin care products

Pubblicato online: 24 Mar 2022
Volume & Edizione: Volume 15 (2022) - Edizione 1 (January 2022)
Pagine: 1 - 11
Dettagli della rivista
Prima pubblicazione
10 Dec 2012
Frequenza di pubblicazione
2 volte all'anno

Due to adverse effects of free radicals on human skin and increasing consumer demand for natural ingredients, essential oils from basil, Ceylon cinnamon bark, clove, juniper, lavender, oregano, rosemary, tea tree, thyme, and ylang-ylang were assessed for their antiradical activity. The oils were evaluated in the concentration range of 5—0.1 mg·mL−1, in which the three reference synthetic antioxidants are most often added to mass-produced cosmetics. Among all examined samples, C. cinnamon oil at a concentration of 5 mg·mL−1 showed the strongest DPPH radical scavenging activity (0.41 mg·mL−1 IC50), followed by clove oil, BHA, α-tocopherol, and BHT (0.82, 0.84, 0.88 and 0.93 mg·mL−1 IC50), respectively. At the same concentration, the reduction power of C. cinnamon oil was higher (1.64 mg·mL−1 Trolox Eq.) than that of α-tocopherol and BHT (1.42 and 0.80 mmol·L−1 Trolox Eq., respectively) but lower than that of BHA (1.81 mmol·L–1 Trolox Eq.). Antiradical activity of the other eight essential oils was low or negligible. C. cinnamon oil and clove oil are promising antiradical agents for skin care but according to our GC-MS analysis, these oils contain 0.29 % of cinnamaldehyde, 0.03 % of linalool, 0.02 % of D-limonene, and 0.02 % of eugenol or 0.41 % of eugenol and 0.002 % of linalool, respectively, which are monitored contact allergens in cosmetics. Such a product is not be suitable for consumers allergic to these substances but for the vast majority of consumers it does not pose a risk in terms of allergic manifestations.


Abdelwahab SI, Mariod AA, Taha MME, Zaman FQ, Abdelmageed AHA, Khamis S, Sivasothy Y, Awang (2017) Arab. J. Chem. 10(1): 131—135. Search in Google Scholar

Abelan US, de Oliva AC, Cacoci ESP, Martinis TEA, Giacon VM, Velasco MVR, de Castro Lima CRR (2021) J. Cosmet. Dermatol. 00: 1—12. Search in Google Scholar

Ácsová A, Hojerová J, Tobolková B, Martiniaková S (2021) Chem. Sel. 6: 4495—4505. Search in Google Scholar

Ahmad A, Van Vuuren S, Viljoen A (2014) Molecules 19(3): 2896—2910.10.3390/molecules19032896627104324662066 Search in Google Scholar

Alam MN, Bristi NJ, Rafiquzzaman M (2013) Saudi Pharm. J. 21: 143—152. Search in Google Scholar

Akar Z, Küçük M, Doğan H (2017) J. Enzyme Inhib. Med. Chem. 32(1): 640—647.10.1080/14756366.2017.1284068600995428262029 Search in Google Scholar

Amelia B, Saepudin E, Cahyana AH, Rahayu DU, Sulistyoningrum AS, Haib J (2017) AIP Conference Proceedings. 1862,030082. Search in Google Scholar

Arantes SM, Picarra A, Guerreiro M, Salvador C, Candeias F, Calderia AT, Martins MR (2019) Food Chem. Toxicol. 133: 110747. Search in Google Scholar

Behbahani BA, Falah F, Arab FL, Vasiee M, Yazdi FT (2020) Evid Based Complement Alternat. Med. 2: 1—8. Search in Google Scholar

Benzie IFF, Strain JJ (1996) Anal. Biochem. 239: 7—76. Search in Google Scholar

Brainina K, Stozhko N, Vidrevich M (2019) Antioxidants (Basel). 8(8): 297. Search in Google Scholar

Brand-Williams W, Cuvelier ME, Berset C (1995) Food Sci. Technol. 1: 25—30. Search in Google Scholar

Chaieb K, Hajlaoui H, Zmantar T, Kahla-Nakbi AB, Rouabhia M, Mahdouani K, Bakhrouf A (2007) Phytother. Res. 24(6): 501—506. Search in Google Scholar

Chen Z, Bertin R, Froldi G (2013) Food Chem. 138(1): 414—420. Search in Google Scholar

CIR (2019) Expert Panel for Cosmetic Ingredient Safety. Safety Assessment of BHT as Used in Cosmetics, 1—92. https://www.cir-safety.org/sites/default/files/BHT.pdf Search in Google Scholar

Coy-Barrera E (2020) Analysis of betalains (betacyanins and betaxanthins) In Recent Advances in Natural Products Analysis, Chapter 17.4.1 Antiradical and antioxidant activity, 593—619. Search in Google Scholar

Echegaray N, Pateiro M, Munekata PES, Lorenzo JM, Chabani Z, Farag MA, Domínguez R (2021) Molecules. 26: 3880—3900. Search in Google Scholar

EI-Ghorab AH, EI-Massry KF (2013) J. Ess. Oil Bear Plants. 6(1): 9—20. Search in Google Scholar

EC (2020) European Parliament and the Council. Regulation (EC) No 1223/2009 on Cosmetic Products (recast). Off. J. EU, L 342/59; consolidated version 01/05/2020. Search in Google Scholar

Fiume MM, Bergfeld WF, Belsito DV (2018) Int. J. Toxicol. 37(2): 61S—94S.10.1177/109158181879445530235959 Search in Google Scholar

Gotmare S (2018) JETIR 5(6): 21—25.10.12968/nuwa.2018.25.21 Search in Google Scholar

Gulcin I, Elmastas M, Aboul-Enein HY (2012) Arab. J. Chem. 5: 489—499. Search in Google Scholar

Hatwalne MS (2012) Indian J. Anaesth. 56(3): 227—233. Search in Google Scholar

Hojerová J, Martiniaková S (2021) Cosmetic Chemistry and Technology (in Slovak). Book. Spectrum STU, Bratislava, 235 pgs. Search in Google Scholar

Horvathova E, Navarova J, Galova E, Sevcovicova A, Chodakova L, Snahnicanova Z, Melusova M, Kozics K, Slamenova D (2014) J. Agric. Food Chem. 62(28): 6632—6639.10.1021/jf501006y24955655 Search in Google Scholar

Kačániová M, Galovičová L, Valková V, Tvrdá E, Terentjeva M, Žiarovská J, Kunová S, Savitskaya T, Grinshpan D, Štefániková J, Felsöciová S, Vukovic N, Kowalczewski PL (2021) Open Chemistry. 19: 214—227. Search in Google Scholar

Labat-Robert J, Robert L (2014). Pathol. Biol. 62(2): 61—66. Search in Google Scholar

L’Oréal Group Website (2020) BHT. https://inside-ourproducts.loreal.com/ingredients/bht Search in Google Scholar

Mahomoodally F, Aumeeruddy-Elalfi Z, Venugopala KN, Hosenally M (2019) Saudi J. Biol. Sci. 26: 1779—1788. Search in Google Scholar

Marchi, RC, Campos IAS, Santana VT, Carlos RM (2022) Coord. Chem. Rev. 451(1): 214275. Search in Google Scholar

Nabavi SF, Di Lorenzo A, Iz adi M, Sobarzo-Sánchez E, Daglia M, Nabavi SM (2015) Nutrients. 7(9): 7729—7748. Search in Google Scholar

Nanasombat S, Wimuttigosol P (2011) Food Sci. Technol. 20: 45—53. Search in Google Scholar

Olszowy M, Dawidowicz A (2016) Monatsh Chem. 147: 2083—2091. Search in Google Scholar

Ortuño J, Serrano R, Jordán MJ, Bañón S (2016) Food Chem. 190: 1056—1063. Search in Google Scholar

Phaniendra A, Jestadi DB, Periyasamy L (2015) Indian J. Clin. Biochem. 30(1): 11—26.10.1007/s12291-014-0446-0431083725646037 Search in Google Scholar

Pizzino G, Irrera N, Cucinotta M, Pallio G, Mannino F, Arcoraci V, Squadrito F, Altavilla D, Bitto A (2017) Oxid. Med. Cell. Longev. 8416763. Search in Google Scholar

Poljšak B, Dahmane R (2012) Derm atol. Res. Pract. 135206, 4 pgs.10.1155/2012/135206329923022505880 Search in Google Scholar

Rao PV, Gan SH (2014) Evid. Based Compl. Alternat. Med. 642942. Search in Google Scholar

Ribeiro JS, Santos MJMC, Silva LKR, Pereira LCL, Santos IAS, da Silva Lannes SC, da Silva MV (2019) Meat Sci. 148: 181—188. Search in Google Scholar

Rodríguez JDW, Peyron S, Rigou, P, Chalier P (2018) PLoS One. 13(11): e0207401. Search in Google Scholar

Sarkic A, Stappen (2018) Cosmetics. 5(1): 11. Search in Google Scholar

SCCS (2011) Scientific Committee on Consumer Safety. Opinion on Fragrance allergens in cosmetic products. SCCS/1459/11. European Commission Health & Consumers. 1—136. Search in Google Scholar

Sharma UK, Sharma AK, Pandey AK (2016) BMC Compl. Alter. Med. 16: 156. Search in Google Scholar

Sudarikov DV, Krymskaya YV, Melekhin AK, Shevchenk OG, Rubtsova SA (2021) Chem. Pap. 75: 2957—2963. Search in Google Scholar

Suryanti V, Wibowo FR, Khotijah S, Andaluck N (2018) IOP Conf. Ser. Mater. Sci. Eng. 333 012077. Search in Google Scholar

Tanaka Y, Uchi H, Furue M (2019) J. Dermatol. Sci. 96 (3): 151—158.10.1016/j.jdermsci.2019.11.00131735467 Search in Google Scholar

Tepe AS, Ozaslan M (2020) Ind. Crops. Prod. 145: 112069. Search in Google Scholar

Wang HF, Yih KH, Yang CHS, Huang FF (2017) J. Food Drug. Anal. 25: 881—889. Search in Google Scholar

Weeratunga HD, Ganegamage SK, Premakumara S (2015) Conference: The 35th Annual Sessions of the Institute of Biology at Sri Lanka. Search in Google Scholar

Weintraub GS, Lai IN, Kim CN (2015) World J. Dermatol. 4: 95—102. Search in Google Scholar

Wong YC, Ahmad-Mudzaqqir MY, Wan-Nurdiyana WA (2014) Orient J. Chem. 30(1): 37—47. Search in Google Scholar

Yang Y-L, Al-Mahdy DA, Wu M-L, Zheng X-T, Piao X-H, Chen A-L, Wang S-M, Yang Q, Ge Y-W (2022) Food Chem. 366(1): 130576. Search in Google Scholar

Yang X, Sun Z, Wang W, Zhou Q, Shi G, We F, Jiang G (2018) Sci. Total Environ. 643: 559—568.10.1016/j.scitotenv.2018.06.21329945090 Search in Google Scholar

Articoli consigliati da Trend MD

Pianifica la tua conferenza remota con Sciendo