<abstract xmlns="http://www.w3.org/1999/xhtml"><p>The present study investigates the potential role of medicinal plants <italic>Citrullus colocynthis</italic> and <italic>Tephrosia apollinea</italic> in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in <italic>n</italic>-hexane, chloroform, <italic>n</italic>-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of <italic>T</italic>. <italic>apollinea</italic> leaf, stem and root have higher TPC compared to those of <italic>C. colocynthis</italic>. Similarly, the results of the present study revealed higher bioactivity of <italic>C. colocynthis</italic> than that of <italic>T</italic>. <italic>apollinea</italic> in various antioxidant assays. Various plant parts of each plant were also compared.</p></abstract>

The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress developed during the generation of reactive oxygen species. Organic extracts of different organs (leaf, stem and root) of these medicinal plants obtained in n-hexane, chloroform, n-butanol and water were assayed for radical scavenging, total antioxidant capacity, anti-lipid peroxidation and reduced glutathione. The total phenolic content (TPC) of both selected medicinal plants was also evaluated. The results indicated that extracts of T. apollinea leaf, stem and root have higher TPC compared to those of C. colocynthis. Similarly, the results of the present study revealed higher bioactivity of C. colocynthis than that of T. apollinea in various antioxidant assays. Various plant parts of each plant were also compared.

In <italic>vitro</italic> oxidative stress regulatory potential of <italic>Citrullus colocynthis</italic> and <italic>Tephrosia apollinea</italic>

UoN Chair of Oman’s Medicinal Plants and Marine Natural Products

Department of Biological Science and Chemistry

Kohat University of Science and Technology

Acta Pharmaceutica

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

In  oxidative stress regulatory potential of  and 

The present study investigates the potential role of medicinal plants Citrullus colocynthis and Tephrosia apollinea in ameliorating the oxidative stress...

In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea

Pubblicato online: 26 apr 2018

Pagine: 235 - 242

Accettato: 04 dic 2017

DOI: https://doi.org/10.2478/acph-2018-0012

Parole chiave
oxidative stress, total phenolics

© 2018 Tania Shamim Rizvi et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

In vitro oxidative stress regulatory potential of Citrullus colocynthis and Tephrosia apollinea

Pubblicato online: 26 apr 2018

Pagine: 235 - 242

Accettato: 04 dic 2017

DOI: https://doi.org/10.2478/acph-2018-0012

Parole chiaveoxidative stress, total phenolics

© 2018 Tania Shamim Rizvi et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
oxidative stress, total phenolics