This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Zhai XW, Cheng FWT, Lee V, Leung WK, Ng MHL, Tsang KS, et al. Improved survival outcome of childhood acute myeloid leukemia with intensified chemotherapy in Chinese children. Pediatr Hematol Oncol. 2011; 28:269–78.ZhaiXWChengFWTLeeVLeungWKNgMHLTsangKSImproved survival outcome of childhood acute myeloid leukemia with intensified chemotherapy in Chinese children2011282697810.3109/08880018.2010.53324921345081Search in Google Scholar
Vedi A, Mitchell R, Shanmuganathan S, Oswald C, Marshall GM, Trahair T, et al. Increased survival for children with acute myeloid leukemia results from improved postrelapse treatment. J Pediatr Hematol Oncol. 2018; 40:541–7.VediAMitchellRShanmuganathanSOswaldCMarshallGMTrahairTIncreased survival for children with acute myeloid leukemia results from improved postrelapse treatment201840541710.1097/MPH.000000000000121529794644Search in Google Scholar
Creutzig U, van den Heuvel-Eibrink MM, Gibson B, Dworzak MN, Adachi S, de Bont E, et al. Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel. Blood. 2012; 120:3187–205.CreutzigUvan den Heuvel-EibrinkMMGibsonBDworzakMNAdachiSde BontEDiagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel2012120318720510.1182/blood-2012-03-36260822879540Search in Google Scholar
Kairiene I, Pasauliene R, Lipunova N, Vaitkeviciene G, Rageliene L, Rascon J. Improved outcome of childhood acute myeloid leukemia in an Eastern European country: Lithuanian experience. Eur J Pediatr. 2017; 176:1329–37.KairieneIPasaulieneRLipunovaNVaitkevicieneGRagelieneLRasconJImproved outcome of childhood acute myeloid leukemia in an Eastern European country: Lithuanian experience201717613293710.1007/s00431-017-2978-928812191Search in Google Scholar
Rubnitz JE. How I treat pediatric acute myeloid leukemia. Blood. 2012; 119:5980–8.RubnitzJEHow I treat pediatric acute myeloid leukemia20121195980810.1182/blood-2012-02-392506338301322566607Search in Google Scholar
Klein K, de Haas V, Kaspers GJL. Clinical challenges in de novo pediatric acute myeloid leukemia. Expert Rev Anticancer Ther. 2018; 18:277–93.KleinKde HaasVKaspersGJLClinical challenges in de novo pediatric acute myeloid leukemia2018182779310.1080/14737140.2018.142809129338495Search in Google Scholar
Lins MM, Mello MJG, Ribeiro RC, De Camargo B, de Fátima Pessoa Militão, de Albuquerque M, Thuler LCS. Survival and risk factors for mortality in pediatric patients with acute myeloid leukemia in a single reference center in low–middle-income country. Ann Hematol. 2019; 98:1403–11.LinsMMMelloMJGRibeiroRCDe CamargoBde Fátima PessoaMilitãode AlbuquerqueMThulerLCSSurvival and risk factors for mortality in pediatric patients with acute myeloid leukemia in a single reference center in low–middle-income country20199814031110.1007/s00277-019-03661-730915498Search in Google Scholar
Xing S, Wang B, Gao Y, Li M, Wang T, Sun Y, et al. Cytogenetics and associated mutation profile in patients with acute monocytic leukemia. Int J Lab Hematol. 2019; 41:485–92.XingSWangBGaoYLiMWangTSunYCytogenetics and associated mutation profile in patients with acute monocytic leukemia2019414859210.1111/ijlh.1303031099482Search in Google Scholar
Iijima-Yamashita Y, Matsuo H, Yamada M, Deguchi T, Kiyokawa N, Shimada A, et al. Multiplex fusion gene testing in pediatric acute myeloid leukemia. Pediatr Int. 2018; 60:47–51.Iijima-YamashitaYMatsuoHYamadaMDeguchiTKiyokawaNShimadaAMultiplex fusion gene testing in pediatric acute myeloid leukemia201860475110.1111/ped.1345129105243Search in Google Scholar
Vujkovic M, Attiyeh EF, Ries RE, Goodman EK, Ding Y, Kavcic M, et al. Genomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children's Oncology Group report. Blood. 2017; 129:3051–8.VujkovicMAttiyehEFRiesREGoodmanEKDingYKavcicMGenomic architecture and treatment outcome in pediatric acute myeloid leukemia: a Children's Oncology Group report20171293051810.1182/blood-2017-03-772384546584028411282Search in Google Scholar
McNeer NA, Philip J, Geiger H, Ries RE, Lavallée VP, Walsh M, et al. Genetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia. Leukemia. 2019; 33:1934–43.McNeerNAPhilipJGeigerHRiesRELavalléeVPWalshMGenetic mechanisms of primary chemotherapy resistance in pediatric acute myeloid leukemia20193319344310.1038/s41375-019-0402-3668754530760869Search in Google Scholar
Pession A, Masetti R, Rizzari C, Putti MC, Casale F, Fagioli F, et al. Results of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia. Blood. 2013; 122:170–8.PessionAMasettiRRizzariCPuttiMCCasaleFFagioliFResults of the AIEOP AML 2002/01 multicenter prospective trial for the treatment of children with acute myeloid leukemia2013122170810.1182/blood-2013-03-49162123673857Search in Google Scholar
Subspecialty Group of Hematology Diseases; Society of Pediatrics; Chinese Medical Association; Editorial Board of Chinese Journal of Pediatrics, Lungjun G, et al. [Recommendations for diagnosis and treatment of acute myelocytic leukemia in children]. Zhonghua Er Ke Za Zhi. [Chin J Pediatr]. 2006; 44:877–8. [in Chinese]Subspecialty Group of Hematology Diseases; Society of Pediatrics; Chinese Medical Association; Editorial Board of Chinese Journal of PediatricsLungjunG[Recommendations for diagnosis and treatment of acute myelocytic leukemia in children]2006448778[in Chinese]Search in Google Scholar
Collins GS, Reitsma JB, Altman DG, Moons KG. Transparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): The TRIPOD statement. Br J Cancer. 2015; 112:251–9.CollinsGSReitsmaJBAltmanDGMoonsKGTransparent reporting of a multivariable prediction model for individual prognosis or diagnosis (TRIPOD): The TRIPOD statement2015112251910.1161/CIRCULATIONAHA.114.014508429722025561516Search in Google Scholar
O’Donnell MR, Tallman MS, Abboud CN, Altman JK, Appelbaum FR, Arber DA, et al. Acute myeloid leukemia, version 3.2017, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2017; 15:926–57.O’DonnellMRTallmanMSAbboudCNAltmanJKAppelbaumFRArberDAAcute myeloid leukemia, version 3.2017, NCCN Clinical Practice Guidelines in Oncology2017159265710.6004/jnccn.2017.011628687581Search in Google Scholar
Jastaniah W, Bayoumy M, Alsultan A, Al Daama S, Ballourah W, Al-Anzi F, et al. Identifying prognostic factors that influence outcome of childhood acute myeloid leukemia in first relapse in Saudi Arabia: results of the multicenter SAPHOS Study. Clin Lymphoma Myeloma Leuk. 2018; 18:773–80.JastaniahWBayoumyMAlsultanAAl DaamaSBallourahWAl-AnziFIdentifying prognostic factors that influence outcome of childhood acute myeloid leukemia in first relapse in Saudi Arabia: results of the multicenter SAPHOS Study2018187738010.1016/j.clml.2018.09.00130340992Search in Google Scholar
Ruan M, Wang Y-Q, Zhang L, Zou Y, Zhu X-F. [Analyses of karyotypic characteristics and prognosis in pediatric acute myeloblastic leukemia]. Zhonghua Xue Ye Xue Za Zhi. [Chin J Hematol]. 2012; 33:725–8. [in Chinese, English abstract].RuanMWangY-QZhangLZouYZhuX-F[Analyses of karyotypic characteristics and prognosis in pediatric acute myeloblastic leukemia]2012337258[in Chinese, English abstract].Search in Google Scholar
Sandahl JD, Kjeldsen E, Abrahamsson J, Ha SY, Heldrup J, Jahnukainen K, et al. Ploidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study. Genes Chromosomes Cancer. 2014; 53:667–75.SandahlJDKjeldsenEAbrahamssonJHaSYHeldrupJJahnukainenKPloidy and clinical characteristics of childhood acute myeloid leukemia: A NOPHO-AML study2014536677510.1002/gcc.2217724753324Search in Google Scholar
So C-C, Wan TS, Chow JL, Hui K-C, Choi WW, Lam CC, Chan L-C. A single-center cytogenetic study of 629 Chinese patients with de novo acute myeloid leukemia—evidence of major ethnic differences and a high prevalence of acute promyelocytic leukemia in Chinese patients. Cancer Genet. 2011; 204:430–8.SoC-CWanTSChowJLHuiK-CChoiWWLamCCChanL-CA single-center cytogenetic study of 629 Chinese patients with de novo acute myeloid leukemia—evidence of major ethnic differences and a high prevalence of acute promyelocytic leukemia in Chinese patients2011204430810.1016/j.cancergen.2011.06.00321962893Search in Google Scholar
Krauth MT, Eder C, Alpermann T, Bacher U, Nadarajah N, Kern W, et al. High number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome. Leukemia. 2014; 28:1449–58.KrauthMTEderCAlpermannTBacherUNadarajahNKernWHigh number of additional genetic lesions in acute myeloid leukemia with t(8;21)/RUNX1-RUNX1T1: frequency and impact on clinical outcome20142814495810.1038/leu.2014.424402164Search in Google Scholar
Harrison CJ, Hills RK, Moorman AV, Grimwade DJ, Hann I, Webb DKH, et al. Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12. J Clin Oncol. 2010; 28:2674–81.HarrisonCJHillsRKMoormanAVGrimwadeDJHannIWebbDKHCytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 1220102826748110.1200/JCO.2009.24.899720439644Search in Google Scholar
Testi AM, Biondi A, Lo Coco F, Moleti ML, Giona F, Vignetti M, et al. GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children. Blood. 2005; 106:447–453.TestiAMBiondiALo CocoFMoletiMLGionaFVignettiMGIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children200510644745310.1182/blood-2004-05-197115677559Search in Google Scholar
Betts DR, Ammann RA, Hirt A, Hengartner H, Beck-Popovic M, Kuhne T, et al. The prognostic significance of cytogenetic aberrations in childhood acute myeloid leukaemia. A study of the Swiss Paediatric Oncology Group (SPOG). Eur J Haematol. 2007; 78:468–76.BettsDRAmmannRAHirtAHengartnerHBeck-PopovicMKuhneTThe prognostic significance of cytogenetic aberrations in childhood acute myeloid leukaemia. A study of the Swiss Paediatric Oncology Group (SPOG)2007784687610.1111/j.1600-0609.2007.00854.x17419750Search in Google Scholar
Kömür M, Erbey F, Bayram I, Tanyeli A. Incidence and prognostic importance of molecular genetic defects in children with acute myeloblastic leukemia. Asian Pac J Cancer Prev. 2010; 11:1393–5.KömürMErbeyFBayramITanyeliAIncidence and prognostic importance of molecular genetic defects in children with acute myeloblastic leukemia20101113935Search in Google Scholar
Moarii M, Papaemmanuil E. Classification and risk assessment in AML: integrating cytogenetics and molecular profiling. Hematology Am Soc Hematol Educ Program. 2017; 2017:37–44.MoariiMPapaemmanuilEClassification and risk assessment in AML: integrating cytogenetics and molecular profiling20172017374410.1182/asheducation-2017.1.37614260529222235Search in Google Scholar
Gong XY, Wang Y, Liu BC, Wei H, Li CW, Li QH, et al. [Characteristics and prognosis in adult acute myeloid leukemia patients with MLL gene rearrangements]. Zhonghua Xue Ye Xue Za Zhi [Chin J Hematol]. 2018; 39:9–14. [in Chinese, English abstract]GongXYWangYLiuBCWeiHLiCWLiQH[Characteristics and prognosis in adult acute myeloid leukemia patients with MLL gene rearrangements]201839914[in Chinese, English abstract]Search in Google Scholar
He J, Xue Y, He H, Li J, Song X, Huang Y, et al. [Clinical and biological characteristics in childhood acute myeloid leukemia with 8;21 translocation]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi [Chin J Med Genetics]. 2004; 21:512–4. [in Chinese, English abstract].HeJXueYHeHLiJSongXHuangY[Clinical and biological characteristics in childhood acute myeloid leukemia with 8;21 translocation]2004215124[in Chinese, English abstract].Search in Google Scholar
Patnaik MM. The importance of FLT3 mutational analysis in acute myeloid leukemia. Leuk Lymphoma. 2018; 59:2273–86.PatnaikMMThe importance of FLT3 mutational analysis in acute myeloid leukemia20185922738610.1080/10428194.2017.139931229164965Search in Google Scholar
Wang CL, Ding BJ, Jiang L, Yin CX, Zhong QX, Yu GP, et al. Increased expression of amyloid precursor protein promotes proliferation and migration of AML1/ETO-positive leukemia cells and be inhibited by panobinostat. Neoplasma. 2015; 62:864–71.WangCLDingBJJiangLYinCXZhongQXYuGPIncreased expression of amyloid precursor protein promotes proliferation and migration of AML1/ETO-positive leukemia cells and be inhibited by panobinostat2015628647110.4149/neo_2015_10526458322Search in Google Scholar
Kim M, Kim J, Kim JR, Han E, Park J, Lim J, et al. FLT3 expression and IL10 promoter polymorphism in acute myeloid leukemia with RUNX1-RUNX1T1. Mol Biol Rep. 2015; 42:451–6.KimMKimJKimJRHanEParkJLimJFLT3 expression and IL10 promoter polymorphism in acute myeloid leukemia with RUNX1-RUNX1T1201542451610.1007/s11033-014-3786-125287662Search in Google Scholar
Ding C, Chen S-N, Macleod RAF, Drexler HG, Nagel S, Wu D-P, et al. MiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death. Ups J Med Sci. 2018; 123:19–27.DingCChenS-NMacleodRAFDrexlerHGNagelSWuD-PMiR-130a is aberrantly overexpressed in adult acute myeloid leukemia with t(8;21) and its suppression induces AML cell death2018123192710.1080/03009734.2018.1440037590146529493383Search in Google Scholar
Debaize L, Jakobczyk H, Avner S, Gaudichon J, Rio A-G, Sérandour AA, et al. Interplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation. Nucleic Acids Res. 2018; 46:11214–228.DebaizeLJakobczykHAvnerSGaudichonJRioA-GSérandourAAInterplay between transcription regulators RUNX1 and FUBP1 activates an enhancer of the oncogene c-KIT and amplifies cell proliferation2018461121422810.1093/nar/gky756626545830500954Search in Google Scholar
Kawashima N, Akashi A, Nagata Y, Kihara R, Ishikawa Y, Asou N, et al. Clinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study. Ann Hematol. 2019; 98:83–91.KawashimaNAkashiANagataYKiharaRIshikawaYAsouNClinical significance of ASXL2 and ZBTB7A mutations and C-terminally truncated RUNX1-RUNX1T1 expression in AML patients with t(8;21) enrolled in the JALSG AML201 study201998839110.1007/s00277-018-3492-530251205Search in Google Scholar