Occurrence of microcystins and anatoxin-a in eutrophic lakes of Saint Petersburg, Northwestern Russia

Apeldoorn, M.E.v., Egmond, H.P.v., Speijers, G.J.A. & Bakker G.J.I. (2007). Toxins of cyanobacteria. Mol. Nutr. Food Res. 51: 7-60. Apeldoorn,M.E.v.,Egmond,H.P.v.,Speijers,G.J.A.BakkerG.J.I.2007Toxins of cyanobacteria.Mol. Nutr. Food Res5176010.1002/mnfr.200600185Search in Google Scholar

Babanazarova, O.V., Sidelev, S.I., Aleksandrina, E.M., Sakharova, E.G. & Kurmayer, R. (2011). Phytoplankton structure and microcystine concentration in the highly eutrophic Nero Lake. Water Resources 38(2): 229-236. 10.1134/S0097807811020023. Babanazarova,O.V.Sidelev,S.I.Aleksandrina,E.M.Sakharova,E.G.Kurmayer,R.2011Phytoplankton structure and microcystine concentration in the highly eutrophic Nero Lake.Water Resources38(38)22923610.1134/S0097807811020023Open DOISearch in Google Scholar

Belykh, O.I., Gladkikh, A.S., Sorokovikova, E.G., Tikhonova, I.V. & Butina, T.V. (2015). Identification of toxic Cyanobacteria in Lake Baikal. Dokl. Biochem. Biophys. 463(1): 220-224. 10.1134/S1607672915040067. Belykh,O.I.Gladkikh,A.S.Sorokovikova,E.G.Tikhonova,I.V.Butina,T.V.2015Identification of toxic Cyanobacteria in Lake Baikal.Dokl. Biochem. Biophys.463(463)22022410.1134/S1607672915040067Open DOISearch in Google Scholar

Bittencourt-Oliveira, M.C., Santos, D.M.S. & Moura, N.A. (2010). Toxic cyanobacteria in reservoirs in northeastern Brazil: detection using a molecular method. Braz. J. Biol. 70(4): 1005-1010. DOI:10.1590/S1519-69842010000500012. Bittencourt-Oliveira,M.C.,Santos,D.M.S.Moura,N.A.2010Toxic cyanobacteria in reservoirs in northeastern Brazil: detection using a molecular method.Braz. J. Biol70(70)10051010DOI:10.1590/S1519-69842010000500012Open DOISearch in Google Scholar

Briand, E., Gugger, M., Francois, J.-Ch., Bernard, C., Humbert, J.-F. et al. (2008). Temporal Variations in the Dynamics of Potentially Microcystin-Producing Strains in a Bloom-Forming Planktothrix agardhii (Cyanobacterium) Population. Applied and environmental microbiology 74(12): 3839-3848. 10.1128/AEM.02343-07. Briand,E.Gugger,M.Francois,J.-Ch.,Bernard,C.Humbert,J.-F.2008Temporal Variations in the Dynamics of Potentially Microcystin-Producing Strains in a Bloom-Forming Planktothrix agardhii (Cyanobacterium) Population.Applied and environmental microbiology74(74)3839384810.1128/AEM.02343-07Open DOISearch in Google Scholar

Chen, J., Xie, P., Li, L. & Xu, J. (2009). First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage. Toxicol. Sci. 108(1): 81-89. 10.1093/toxsci/kfp009. Chen,J.Xie,P.Li,L.Xu,J.2009First identification of the hepatotoxic microcystins in the serum of a chronically exposed human population together with indication of hepatocellular damage.Toxicol. Sci108(108)818910.1093/toxsci/kfp009Open DOISearch in Google Scholar

Chorus, I. (2012). Current approaches to cyanotoxin risk assessment, risk management and regulations in different countries. Dessau-Rosslau, Germany: Federal Environment Agency (Umweltbundesamt). Retrieved February 15, 2016, from http://www.umweltdaten.de/publikationen/fpdf-l/4390.pdf Chorus,I.2012Current approaches to cyanotoxin risk assessment, risk management and regulations in different countriesDessau-Rosslau, Germany: Federal Environment Agency (Umweltbundesamt). RetrievedFebruary152016fromhttp://www.umweltdaten.de/publikationen/fpdf-l/4390.pdfSearch in Google Scholar

Directive 2006/7/EC of the European Parliament and of the Council of 15 February 2006 concerning the management of bathing water quality and repealing Directive 76/160/EEC. Official Journal of the European Union, 2006, L64:37–51. Retrieved February 15, 2016, from http://eur-lex.europa.eu/LexUriServ/LexUriServ. do?uri=OJ:L:2006:064:0037:0051:EN:PDF Directive 2006/7/EC of the European Parliament and of the Council of 15 February 2006 concerning the management of bathing water quality and repealing Directive 76/160/EEC. Official Journal of the European Union, 2006, L64:37–51. Retrieved February 15, 2016, from http://eur-lex.europa.eu/LexUriServ/LexUriServ. do?uri=OJ:L:2006:064:0037:0051:EN:PDFSearch in Google Scholar

Dimitrakopoulos, I.K., Kaloudis, T.S., Hiskia, A.E., Thomaidis, N.S & Koupparis, M.A. (2010). Development of a fast and selective method for the sensitive determination of anatoxin-a in lake waters using liquid chromatography– tandem mass spectrometry and phenylalanine-d5 as internal standard. Anal. Bioanal. Chem. 397: 2245-2252. 10.1007/s00216-010-3727-3. Dimitrakopoulos,I.K.Kaloudis,T.S.Hiskia,A.E.Thomaidis,N.SKoupparis,M.A.2010Development of a fast and selective method for the sensitive determination of anatoxin-a in lake waters using liquid chromatography– tandem mass spectrometry and phenylalanine-d5 as internal standard.Anal. Bioanal. Chem3972245225210.1007/s00216-010-3727-3Open DOISearch in Google Scholar

Dittmann, E. & Wiegand, C. (2006). Cyanobacterial toxins– occurrence, biosynthesis and impact on human affairs. Mol. Nutr. Food Res. 50: 7-17. 10.1002/mnfr.200500162. Dittmann,E.Wiegand,C.2006Cyanobacterial toxins– occurrence, biosynthesis and impact on human affairs.Mol. Nutr. Food Res5071710.1002/mnfr.200500162Open DOISearch in Google Scholar

Fastner, J., Neumann, U., Wirsing, B., Weckesser, J., Wiedner, C. et al. (1999). Microcystins (hepatotoxic heptapeptides) in German fresh water bodies. Environ. Toxicol. 14: 13-22. 10.1002/(SICI)1522-7278(199905)14:2<291::AID-TOX 11>3.0.CO;2-E. Fastner,J.Neumann,U.Wirsing,B.Weckesser,J.Wiedner,C.1999Microcystins (hepatotoxic heptapeptides) in German fresh water bodies.Environ. Toxicol.14132210.1002/(SICI)1522-7278(199905)14:2<291::AID-TOX 11>3.0.CO;2-EOpen DOISearch in Google Scholar

Furey, A., Allis, O., Ortea, P.M., Lehane, M. & James, K. J. (2008). Hepatotoxins: Context and Chemical Determination. In L.M. Botana (Ed.), Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection (pp. 844-886). Second Edition. Boca Raton: CRC Press Taylor & Francis Group. Furey,A.Allis,O.Ortea,P.M.Lehane,M.James,K. J.2008Hepatotoxins: Context and Chemical Determination. InBotanaL.M.Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection844886Second EditionBoca RatonCRC Press Taylor & Francis GroupSearch in Google Scholar

Grabowska, M. & Mazur-Marzec, H. (2011). The effect of cyanobacterial blooms in the Siemianowska Dam Reservoir on the phytoplankton structure in the Narew River. Ocean. Hydrobiol. Stud. 40(1): 19-26. 10.2478/s13545-011-0003-x. Grabowska,M.Mazur-Marzec,H.2011The effect of cyanobacterial blooms in the Siemianowska Dam Reservoir on the phytoplankton structure in the Narew River.Ocean. Hydrobiol. Stud.40(40)192610.2478/s13545-011-0003-xOpen DOISearch in Google Scholar

Gromov, B.V., Vepritsky, A.A., Mamkaeva, K.A. & Voloshko, L.N. (1996). A survey of toxicity of cyanobacterial blooms in Lake Ladoga and adjacent water bodies. Hydrobiologia 322: 129-136. Gromov,B.V.Vepritsky,A.A.Mamkaeva,K.A.Voloshko,L.N.1996A survey of toxicity of cyanobacterial blooms in Lake Ladoga and adjacent water bodies.Hydrobiologia32212913610.1007/978-94-009-1655-5_23Search in Google Scholar

James, K.J., Dauphard, J., Crowley, J. & Furey, A. (2008). Cyanobacterial Neurotoxins, Anatoxin-A and Analogues: Detection and Analysis. In L. M. Botana (Ed.), Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection (pp. 809-822). Second Edition. Boca Raton: CRC Press Taylor & Francis Group. James,K.J.Dauphard,J.Crowley,J.Furey,A.2008Cyanobacterial Neurotoxins, Anatoxin-A and Analogues: Detection and Analysis. InBotanaL. M.Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection809822Second EditionBoca RatonCRC Press Taylor & Francis Group10.1201/9781420007541.pt13Search in Google Scholar

Kokocinski, M., Stefaniak, K., Izydorczyk, K., Jurczak, T., Mankiewicz-Boczek, J. et al. (2011). Temporal variation in microcystin production by Planktothrix agardhii (Gomont) Anagnostidis and Komárek (Cyanobacteria, Oscillatoriales) in a temperate lake. Ann. Limnol. - Int. J. Lim. 47: 363-371. DOI:10.1051/limn/2011046. Kokocinski,M.Stefaniak,K.Izydorczyk,K.Jurczak,T.Mankiewicz-Boczek,J.2011Temporal variation in microcystin production by Planktothrix agardhii (Gomont) Anagnostidis and Komárek (Cyanobacteria, Oscillatoriales) in a temperate lake.Ann. Limnol. - Int. J. Lim.4736337110.1051/limn/2011046Open DOISearch in Google Scholar

Korneva, L.V., Solovieva, V.V., Zhakovskaya, Z.A., Russkikh, Ia.V. & Chernova E.N. (2014). Phytoplankton and content of cyanotoxins in Rrybinsk, Gorky and Cheboksary Reservoirs during the anomalously hot summer of 2010. Water: Chemistry and Ecology 8: 24-29. (In Russian with English abstract). Korneva,L.V.Solovieva,V.V.Zhakovskaya,Z.A.Russkikh,Ia.V.ChernovaE.N.2014Phytoplankton and content of cyanotoxins in Rrybinsk, Gorky and Cheboksary Reservoirs during the anomalously hot summer of 2010.Water: Chemistry and Ecology82429(In Russian with English abstract)Search in Google Scholar

Kurmayer, R. & Christiansen G. (2009). The genetic basis of toxin production in Cyanobacteria. Freshwater Reviews 2:31-50. 10.1608/FRJ-2.1.2. Kurmayer,R.ChristiansenG.2009The genetic basis of toxin production in Cyanobacteria.Freshwater Reviews2315010.1608/FRJ-2.1.2Open DOISearch in Google Scholar

Lyra, C., Suomalainen, S., Gugger, M., Vezie, Ch., Sundman, P. et al. (2001). Molecular characterization of planktic cyanobacteria of Anabaena, Aphanizomenon, Microcystis and Planktothrix genera. International Journal of Systematic and Evolutionary Microbiology 51: 513-526. Lyra,C.Suomalainen,S.Gugger,M.Vezie,Ch.,Sundman,P.2001Molecular characterization of planktic cyanobacteria of Anabaena, Aphanizomenon, Microcystis and Planktothrix genera.International Journal of Systematic and Evolutionary Microbiology5151352610.1099/00207713-51-2-51311321098Search in Google Scholar

Mayumi, T., Kato, H., Imanishi, S., Kawasaki, Y., Hasegawa, M. et al. (2006). Structural Characterization of Microcystins by LC/MS/MS under Ion Trap Conditions. J. Antibiot. 59(11): 710-719. 10.1038/ja.2006.95. Mayumi,T.Kato,H.Imanishi,S.Kawasaki,Y.Hasegawa,M.2006Structural Characterization of Microcystins by LC/MS/MS under Ion Trap Conditions.J. Antibiot.59(59)71071910.1038/ja.2006.9517256470Open DOISearch in Google Scholar

Neilan, B.A., Pearson, L.A., Muenchhoff , J., Moffitt, M.C. & Dittmann, E. (2013). Environmental conditions that influence toxin biosynthesis in cyanobacteria. Environ. Microbiol. 15(5): 1239-1253. 10.1111/j.1462-2920.2012.02729.x. Neilan,B.A.Pearson,L.A.Muenchhoff ,J.Moffitt,M.C.Dittmann,E.2013Environmental conditions that influence toxin biosynthesis in cyanobacteria.Environ. Microbiol.15(15)1239125310.1111/j.1462-2920.2012.02729.x22429476Open DOISearch in Google Scholar

Nixdorf, B., Mischke, U. & Rucker, J. (2003). Phytoplankton assemblages and steady state in deep and shallow eutrophic lakes – an approach to differentiate the habitat properties of Oscillatoriales. Hydrobiol. 502:111-121. 10.1023/B:HYDR.0000004274.65831.e5. Nixdorf,B.Mischke,U.Rucker,J.2003Phytoplanktonassemblages and steady state in deep and shallow eutrophic lakes – an approach to differentiate the habitat properties of Oscillatoriales.Hydrobiol.50211112110.1023/B:HYDR.0000004274.65831.e5Open DOISearch in Google Scholar

Olenina, I., Hajdu, S., Edler, L., Andersson, A., Wasmund, N. et al. (2006). Biovolumes and size-classes of phytoplankton in the Baltic Sea. Helsinki: HELCOM Balt.Sea Environ. (Proc. No. 106). http://www.helcom.fi /Lists/Publications/BSEP106. pdf Olenina,I.Hajdu,S.Edler,L.Andersson,A.Wasmund,N.2006Biovolumes and size-classes of phytoplankton in the Baltic Sea.HelsinkiHELCOM Balt.Sea Environ. (Proc. No. 106)http://www.helcom.fi /Lists/Publications/BSEP106.pdfSearch in Google Scholar

Osswald, J., Rellan, S., Gago, A. & Vasconcelos, V. (2007). Toxicology and detection methods of the alkaloid neurotoxin produced by cyanobacteria, anatoxin-a. Review. Environ. Int. 33: 1070-1089. Osswald,J.Rellan,S.Gago,A.Vasconcelos,V.2007Toxicology and detection methods of the alkaloid neurotoxin produced by cyanobacteria, anatoxin-a. Review.Environ. Int.331070108910.1016/j.envint.2007.06.00317673293Search in Google Scholar

Ostermaier, V., Schanz, F., Köster, O. & Kurmayer, R. (2012). Stability of toxin gene proportion in red-pigmented populations of the cyanobacterium Planktothrix during 29 years of re-oligotrophication of Lake Zürich. BMC Biology 10: 100-116. 10.1186/1741-7007-10-100. Ostermaier,V.Schanz,F.Köster,O.Kurmayer,R.2012Stability of toxin gene proportion in red-pigmented populations of the cyanobacterium Planktothrix during 29 years of re-oligotrophication of Lake Zürich.BMC Biology1010011610.1186/1741-7007-10-100353463423216925Open DOISearch in Google Scholar

Pawlik-Skowrońska, B., Skowroński, T., Pirszel, J. & Adamczyk, A. (2004). Relationship between cyanobacterial bloom composition and anatoxin-a and microcystin occurrence in the eutrophic dam reservoir (SE Poland). Pol. J. Ecol. 52: 479-490. Pawlik-Skowrońska,B.Skowroński,T.,Pirszel,J.Adamczyk,A.2004Relationship between cyanobacterial bloom composition and anatoxin-a and microcystin occurrence in the eutrophic dam reservoir (SE Poland).Pol. J. Ecol.52479490Search in Google Scholar

Pawlik-Skowrońska, B., Pirszel, J. & Kornijów, R. (2008). Spatial and temporal variation in microcystin concentrations during perennial bloom of Planktothrix agardhii in a hypertrophic lake. Ann. Limnol. Int. J. lim. 44(2): 63-68. 10.1051/limn:2008015. Pawlik-Skowrońska,B.Pirszel,J.Kornijów,R.2008Spatial and temporal variation in microcystin concentrations during perennial bloom of Planktothrix agardhii in a hypertrophic lake.Ann. Limnol. Int. J. lim.44(44)636810.1051/limn:2008015Open DOISearch in Google Scholar

Rantala, A., Rajaniemi-Wacklin, P., Lyra, C., Lepisto, L., Rintala, J. et al. (2006). Detection of microcystins-producing cyanobacteria in Finnish lakes with genus-specific microcystins synthetase gene E (mcyE) PCR and associations with environmental factors. Appl. Environ. Microbiol. 72(9): 6101-6110. 10.1128/AEM.01058-06. Rantala,A.Rajaniemi-Wacklin,P.Lyra,C.Lepisto,L.Rintala,J.2006Detection of microcystins-producing cyanobacteria in Finnish lakes with genus-specific microcystins synthetase gene E (mcyE) PCR and associations with environmental factors.Appl. Environ. Microbiol.72(72)6101611010.1128/AEM.01058-06Open DOISearch in Google Scholar

Rantala-Ylinen, A., Kana, S., Wang, H., Rouhiainen, L., Wahlsten, M. et al. (2011). Anatoxin-a synthetase gene cluster of the cyanobacterium Anabaena sp. strain 37 and molecular methods to detect potential producers. Appl. Environ. Microbiol. 77: 7271-7278. 10.1128/AEM.06022-11. Rantala-Ylinen,A.Kana,S.Wang,H.Rouhiainen,L.Wahlsten,M.2011Anatoxin-a synthetase gene cluster of the cyanobacterium Anabaena sp. strain 37 and molecular methods to detect potential producers.Appl. Environ. Microbiol.777271727810.1128/AEM.06022-11Open DOISearch in Google Scholar

Rohrlack, T., Skulberg, R., Skulberg, O.M. (2009). Distribution of oligopeptides of the cyanobacterium Planktothrix and their persistence in selected lakes in Fennoscandia. J. Phycol. 45:1259-1265. 10.1111/j.1529-8817.2009.00757.x. Rohrlack,T.Skulberg,R.Skulberg,O.M.2009Distribution of oligopeptides of the cyanobacterium Planktothrix and their persistence in selected lakes in Fennoscandia.J. Phycol.451259126510.1111/j.1529-8817.2009.00757.xOpen DOISearch in Google Scholar

Russkikh, Y.V., Chernova, E.N., Voyakina, E. Ju., Nikiforov, V. A. & Zhakovskaya, Z.A. (2012). Cyanotoxin determination in natural water matrix by the method of high performance liquid chromatography- mass-spectrometry of high resolution. Izvestiya St. Peterburgskogo gosudarstvennogo technologicheskogo instituta (tekhnicheskogo universiteta) 17(43): 61-66. (In Russian). Russkikh,Y.V.Chernova,E.N.Voyakina,E. Ju.,Nikiforov,V. A.Zhakovskaya,Z.A.2012Cyanotoxin determination in natural water matrix by the method of high performance liquid chromatography- mass-spectrometry of high resolution.Izvestiya St. Peterburgskogo gosudarstvennogo technologicheskogo instituta (tekhnicheskogo universiteta)17(17)6166(In Russian)Search in Google Scholar

Sidelev, S.I., Golokolenova, T.B., Chernova, E.N., Russkikh, I.V. (2015). Analysis of Phytoplankton in Tsimlyansk Reservoir (RUSSIA) for the Presence of Cyanobacterial Hepato and Neurotoxins. Microbiology 84(6): 828-837. 10.1134/S0026261715060120. Sidelev,S.I.Golokolenova,T.B.Chernova,E.N.Russkikh,I.V.2015Analysis of Phytoplankton in Tsimlyansk Reservoir (RUSSIA) for the Presence of Cyanobacterial Hepato and Neurotoxins.Microbiology84(84)82883710.1134/S0026261715060120Open DOISearch in Google Scholar

Sivonen, K., Namikoshi, M., Luukkainen, R., Fardig, M., Rouhiainen, L. et al. (1995). Variation of cyanobacterial hepatotoxins in Finland. In M. Munawar & M. Luotola (Eds.), The Contaminats in the Nordic Ecosystem: Dynamics, Processes & Fate. Ecovision World Monograph Series (pp. 163-169). SPB Academic Publishing, Amsterdam, The Netherlands. Sivonen,K.Namikoshi,M.Luukkainen,R.Fardig,M.Rouhiainen,L.1995Variation of cyanobacterial hepatotoxins in Finland. InMunawarM.LuotolaM.The Contaminats in the Nordic Ecosystem: Dynamics, Processes & Fate. Ecovision World Monograph Series163169SPB Academic PublishingAmsterdam, The Netherlands10.1533/9781845698164.2.152Search in Google Scholar

Sivonen, K. & Jones, G. (1999). Cyanobacterial toxins. In I. Chorus, J. Bartram (Eds.), Toxic cyanobacteria in water: A guide to the Public Health Consequences, Monitoring and Management (pp. 41-111). London: E & FN Spoon. Sivonen,K.Jones,G.1999Cyanobacterial toxins. InChorus,I.BartramJ.Toxic cyanobacteria in water: A guide to the Public Health Consequences, Monitoring and Management41111LondonE & FN Spoon10.1016/B978-012373944-5.00005-5Search in Google Scholar

Spoof, L., Vesterkvist, P., Lindholm, T. & Meriluoto, J. (2003). Screening for hepatotoxins, microcystins and nodularin in environmental water samples by reversed-phase liquid chromatography- electrospray ionization mass spectrometry. J. Chromatogr. A 1020: 105-119. 10.1016/S0021-9673(03)00428-X. Spoof,L.Vesterkvist,P.Lindholm,T.Meriluoto,J.2003Screening for hepatotoxins, microcystins and nodularin in environmental water samples by reversed-phase liquid chromatography- electrospray ionization mass spectrometry.J. Chromatogr. A102010511910.1016/S0021-9673(03)00428-XOpen DOISearch in Google Scholar

Stefaniak, K., Kokocinski, M. & Messyasz, B. (2005). Dynamics of Planktothrix agardhii (Gom.) Anagn. et Kom. blooms inpolimictic Lake Laskownickie and Grylewskie (Wielkopolska region) Poland. Ocean. Hydrobiol. Stud. 34 (Supl. 3): 125-136. Stefaniak,K.Kokocinski,M.Messyasz,B.2005Dynamics of Planktothrix agardhii (Gom.) Anagn. et Kom. blooms inpolimictic Lake Laskownickie and Grylewskie (Wielkopolska region) Poland.Ocean. Hydrobiol. Stud.34(Supl. 3)125136Search in Google Scholar

Teubner, K., Feyerabend, R., Henning, M., Nicklisch, A., Woitke, P. et al. (1999). Alternative blooming of Aphanizomenon flos-aquae or Planktothrix agardhii induced by the timing of the critical nitrogen: phosphorus ratio in hypertrophic riverine lakes. Arch. Hydrobiol., Spec. Issues Advanc. Limnol. 54: 325-344. Teubner,K.Feyerabend,R.Henning,M.Nicklisch,A.Woitke,P.1999Alternative blooming of Aphanizomenon flos-aquae or Planktothrix agardhii induced by the timing of the critical nitrogen: phosphorus ratio in hypertrophic riverine lakes.Arch. Hydrobiol., Spec. Issues Advanc. Limnol54325344Search in Google Scholar

Tonk, L., Visser, P.M., Christiansen, G., Dittmann, E., Snelder, E.O.F.M. et al. (2005) The microcystin composition of the cyanobacterium Planktothrix agardhii changes towards a more toxic variant with increasing light intensity. Applied and Environmental Microbiology 71: 5177-5181. DOI:10.1128/AEM.71.9.5177–5181.2005. Tonk,L.Visser,P.M.Christiansen,G.Dittmann,E.Snelder,E.O.F.M.2005The microcystin composition of the cyanobacterium Planktothrix agardhii changes towards a more toxic variant with increasing light intensity.Applied and Environmental Microbiology715177518110.1128/AEM.71.9.5177–5181.2005Open DOISearch in Google Scholar

Trifonova, I.S. & Pavlova, O.A. (2008). Phytoplankton succession in urban water-bodies of St. Petersburg as an indicator of their ecological conditions. Limnol. Rev. 8(3): 137-141. Trifonova,I.S.Pavlova,O.A.2008Phytoplankton succession in urban water-bodies of St. Petersburg as an indicator of their ecological conditions.Limnol. Rev8(8)137141Search in Google Scholar

Ueno, Y., Nagata, S., Tsutsumi, T., Hasegawa, A., Watanabe, M.F. et al. (1996). Detection of microcystin, a blue–green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay. Carcinogenesis 17(6): 1317-1321. Ueno,Y.Nagata,S.Tsutsumi,T.Hasegawa,A.Watanabe,M.F.1996Detection of microcystin, a blue–green algal hepatotoxin, in drinking water sampled in Haimen and Fusui, endemic areas of primary liver cancer in China, by highly sensitive immunoassay.Carcinogenesis17(17)1317132110.1093/carcin/17.6.13178681449Search in Google Scholar

van der Merwe, D., Sebbag, L., Nietfeld, J.C., Aubel, M.T., Foss, A. et al. (2012). Investigation of a Microcystis aeruginosa cyanobacterial freshwater harmful algal bloom associated with acute microcystin toxicosis in a dog. J. Vet. Diagn. Invest. 24 (4): 679-687. 10.1177/1040638712445768. van der Merwe,D.Sebbag,L.Nietfeld,J.C.Aubel,M.T.Foss,A.2012Investigation of a Microcystis aeruginosa cyanobacterial freshwater harmful algal bloom associated with acute microcystin toxicosis in a dog.J. Vet. Diagn. Invest.24467968710.1177/104063871244576822604771Open DOISearch in Google Scholar

Voloshko, L., Kopecky, J., Safronova, T., Pljusch, A., Titova, N. et al. (2008). Toxins and other bioactive compounds produced by cyanobacteria in Lake Ladoga. Estonian J. of Ecology 57(2): 100-110. 10.3176/eco.2008.2.02. Voloshko,L.Kopecky,J.Safronova,T.Pljusch,A.Titova,N.2008Toxins and other bioactive compounds produced by cyanobacteria in Lake Ladoga.Estonian J. of Ecology57(57)10011010.3176/eco.2008.2.02Open DOISearch in Google Scholar

Welker, M. (2008). Cyanobacterial Hepatotoxins: Chemistry, Biosynthesis, and Occurrence. In L.M. Botana (Ed.), Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection (pp. 825-844). Second Edition. Boca Raton: CRC Press Taylor & Francis Group. Welker,M.2008Cyanobacterial Hepatotoxins: Chemistry,Biosynthesis, and Occurrence. InBotanaL.M.Seafood and Freshwater Toxins. Pharmacology, Physiology and Detection825844Second EditionBoca RatonCRC Press Taylor & Francis Group10.1201/9781420007541.ch39Search in Google Scholar

Wiedner, C., Visser, P.M., Fastner, J., Metcalf, J.S., Codd, G.A. et al. (2003). Effects of light on the microcystin content of Microcystis strain PCC 7806. Appl. Environ. Microbiol. 69 (3): 1475-1481. Wiedner,C.Visser,P.M.Fastner,J.Metcalf,J.S.Codd,G.A.2003Effects of light on the microcystin content of Microcystis strain PCC 7806.Appl. Environ. Microbiol.6931475148110.1128/AEM.69.3.1475-1481.200315006512620831Search in Google Scholar

WHO. (2003). Guidelines for safe recreational water environments. Vol. 1. Coastal and fresh waters. Geneva: World Health Organization. Retrieved December 30, 2015, from http://www.who.int/water_sanitation_health/bathing/srwe1/en WHO.2003Guidelines for safe recreational water environments1Coastal and fresh watersGenevaWorld Health OrganizationRetrievedDecember302015fromhttp://www.who.int/water_sanitation_health/bathing/srwe1/enSearch in Google Scholar

WHO. (2011). Guidelines for Drinking Water Quality. Geneva: World Health Organization. Retrieved December 30, 2015, from http://www.who.int/water_sanitation_health/publications/2011/dwq_guidelines/en WHO.2011Guidelines for Drinking Water QualityGenevaWorld Health OrganizationRetrievedDecember302015fromhttp://www.who.int/water_sanitation_health/publications/2011/dwq_guidelines/enSearch in Google Scholar

Xing, W., Huang, W.M., Liu, Y.D., Li, D.H., Shen, Y.W. et al. (2007). Environmental mechanism of change in cyanobacterial species composition in the Northeastern part of Lake Di anchi (China). Fresenius Environmental Bulletin 16(1): 82-90. Xing,W.Huang,W.M.Liu,Y.D.Li,D.H.Shen,Y.W.2007Environmental mechanism of change in cyanobacterial species composition in the Northeastern part of Lake Di anchi (China).Fresenius Environmental Bulletin16(16)8290Search in Google Scholar