<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Resistin is still a little known hormone of the adipose tissue. The potential role of resistin in the development of DM2 has been currently investigated. The aim of our study was to detect the resistin blood level in patients with DM2, depending on the duration of the disease. In so doing, a determination of resistin and insulin blood level was conducted in 305 patients with DM2, and in a control group of 32 persons. Before testing, the patients were placed into four groups, depending on the duration of type 2 diabetes. Our results indicate that the resistin level was significantly lower in the control group of patients, in comparison with the DM2 patients groups. Moreover, a significantly lower resistin level was found in group I (firstly diagnosed DM2), in comparison with the groups of patients with a different duration of DM2. No correlation between resistin level and BMI, and between resistin and insulin blood level was found. However, a tendency towards increase of resistin blood level is noticeably evident in co-relation with increment of DM2 duration. In addition, the resistin level was considerably lower in patients with no DM2, when compared with patients with diagnosed DM2. Yet, there was no significant difference in the resistin blood level depending on the sex of the patients at the same duration of DM2</p></abstract>

Resistin is still a little known hormone of the adipose tissue. The potential role of resistin in the development of DM2 has been currently investigated. The aim of our study was to detect the resistin blood level in patients with DM2, depending on the duration of the disease. In so doing, a determination of resistin and insulin blood level was conducted in 305 patients with DM2, and in a control group of 32 persons. Before testing, the patients were placed into four groups, depending on the duration of type 2 diabetes. Our results indicate that the resistin level was significantly lower in the control group of patients, in comparison with the DM2 patients groups. Moreover, a significantly lower resistin level was found in group I (firstly diagnosed DM2), in comparison with the groups of patients with a different duration of DM2. No correlation between resistin level and BMI, and between resistin and insulin blood level was found. However, a tendency towards increase of resistin blood level is noticeably evident in co-relation with increment of DM2 duration. In addition, the resistin level was considerably lower in patients with no DM2, when compared with patients with diagnosed DM2. Yet, there was no significant difference in the resistin blood level depending on the sex of the patients at the same duration of DM2

The blood resistin level in patients with DM2, depending on the duration of the disease

Department of Endocrinology, Lviv National Medical University, Pekarska 69, 79010, Lviv, Ukraine

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This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Resistin is still a little known hormone of the adipose tissue. The potential role of resistin in the development of DM2 has been currently investigated. The...

The blood resistin level in patients with DM2, depending on the duration of the disease

Pubblicato online: 16 lug 2015

Pagine: 111 - 114

Ricevuto: 27 feb 2015

Accettato: 24 mar 2015

DOI: https://doi.org/10.1515/cipms-2015-0055

Parole chiave
resistin, diabetes mellitus type 2 (DM2), insulin

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The blood resistin level in patients with DM2, depending on the duration of the disease

Pubblicato online: 16 lug 2015

Pagine: 111 - 114

Ricevuto: 27 feb 2015

Accettato: 24 mar 2015

DOI: https://doi.org/10.1515/cipms-2015-0055

Parole chiaveresistin, diabetes mellitus type 2 (DM2), insulin

© 2015

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Parole chiave
resistin, diabetes mellitus type 2 (DM2), insulin