<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Over the last decades, the overall survival rate for childhood cancer has increased from 20% to 80%, which is the result of advances in treatment Nevertheless, most data from the international registers of childhood cancer survivors (CCS) stress that this population of patients is at high risk for late sequelae and their biologica/ aging starts earlier in life. Anticancer therapy (chemotherapy, radiotherapy, surgery, immunotherapy) affects the intracellular processes leading to the chronic deterioration of organ function and premature senescence. The present review focuses on the late effects of anticancer treatment on various human organs that may lead to premature aging.</p></abstract>

Risk factors for premature aging in childhood cancer survivors

<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The placenta serves as a metabolic, respiratory, excretory, and endocrine organ that provides appropriate conditions required for adequate feta/ development during pregnancy. The development of particular structures and proper functioning of the placenta are under the influence of sophisticated pathways controlled by the eexpression of substantial genes that are additionally regulated by long non-coding ribonucleic acids (RNAs). Disruptions to adaptive changes in the placenta/ transcriptome as a response to alterations in the feto-matema/ environment may be associated with pregnancy complications and compromised feta/ outcomes. The aim of the current paper was to present recent findings in transcriptomics of the human placenta. Different approaches in bioinformatic analyses of the RNA-sequencing results were presented. Novel knowledge about the genes and mechanisms that are crucial for the proper development of the placenta is essential for the understanding what stands behind both the norma/ and complicated pregnancy.</p></abstract>

Recent progress in human placental transcriptomics

<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec id="j_devperiodmed.20192302.109116_s_007"><h3>Introduction</h3>
<p>Self-rated health (SRH), an indicator which is extensively used in population studies, constitutes a measure of health closely linked to morbidity, mortality and overall health status and enjoys popularity in surveys monitoring adolescents. Most studies show that at puberty girls assess their health as worse than boys do, and the difference widens with age. Moreover, puberty is a crucial period for health, since it is the time when health risk behaviours are often initiated or become established.</p></sec>
<sec id="j_devperiodmed.20192302.109116_s_008"><h3>Aim</h3>
<p>To analyse the associations between high scores on self-rated health among 15-year-old girls, participants of the Healthy Me programme, and their selected health behaviours.</p></sec>
<sec id="j_devperiodmed.20192302.109116_s_009"><h3>Material and methods</h3>
<p>The study covered a group of 1173 second-grade female students from 48 lower secondary schools located in rural and urban areas of 16 voivodeships all over Poland. The participants answered questions about chronic diseases or disability, self-rated health, diet, leisure activities, physical activity and health risk behaviours. In the statistical analysis, the association between self-rated health and individual indicators of health behaviour was examined using logistic regression.</p></sec>
<sec id="j_devperiodmed.20192302.109116_s_010"><h3>Results</h3>
<p>Two thirds of the girls assessed their health as excellent or good. Only approximately 5% of the respondents made the "extreme negative" assessment. In the final multivariate analysis, five factors remained important predictors of high self-rated health scores: regular participation in physical education classes, vigorous physical activity, daily breakfast consumption, consumption of fruit at least once a day and sleep for at least 8 hours a day.</p></sec>
<sec id="j_devperiodmed.20192302.109116_s_011"><h3>Conclusions</h3>
<p>Regularparticipation in physical education classes, vigorousphysical activity, consumption of breakfast and fruit every day, as well as sleep for at least 8 hours a day are powerful predictors of high scores on self-rated health of 15-year-old adolescent girls.</p>
<p>Public health activities aimed at adolescents should focus on the positive aspects of health and a lifestyle paying special attention on pro health behaviours.</p></sec></abstract>

Behavioural factors as predictors of self-rated health among Polish adolescent girls

<abstract xmlns="http://www.w3.org/1999/xhtml">


<sec id="j_devperiodmed.20192302.117124_s_008">
<h3>Objective</h3>
<p>The aim of the study was to compare the advantages of semi-elevated and side-lying positioning during bottle-feeding of preterm infants ≤34 weeks gestational age (34+0/7).</p>
</sec>
<sec id="j_devperiodmed.20192302.117124_s_009">
<h3>Material and methods</h3>
<p>The study included six neonates (n=6) bom ≤34 weeks gestational age who reached the age ≥32 weeks of postmenstrual age on the day when the study began and were hospitalized in the neonatology ward. Four bottle-feeding sessions were tested in each of the newborns: two in the side-lying and two in the semi-elevated position. The position for the first test was chosen randomly. For each of the positions twelve feeding sessions were examined and each preterm infant hod bottle-feeding sessions analyzed both in the semi-elevated and side-lying positions. The level of saturation and heart rate were measured as the parameters indicative of the newborn's physiological stability. The factors determining the qualitative aspect of feeding included the level of the newborn's alertness and the occurrence of choking episodes. The amount of food consumed and the duration of the feeding were also recorded.</p>
</sec>
<sec id="j_devperiodmed.20192302.117124_s_010">
<h3>Results</h3>
<p>The side-lying position was more effective with regard to the totol amount of sustenance consumed as compared to the semi-elevated feeding position and the study result was statistically significant (p=0.007). The difference in the number of chokes between the study groups was not statistically significant, although a trend towards a reduced number of choking episodes was observed among infants fed in the side-lying position (p=0.090). There were no significant differences in oxygen saturation, heart rate and level of activity between the study groups.</p>
</sec>
<sec id="j_devperiodmed.20192302.117124_s_011">
<h3>Conclusions</h3>
<p>The effects of this pilot study demonstrate the efficacy of the side-lying feeding position regarding the final amount of milk intake. The side-lying position may also reduce the number of choking episodes during the feeding. The results suggest the need to extend the study in order to confirm the potential benefits of using the side-lying position.</p>
</sec>
</abstract>

The impact of positioning on bottle-feeding in preterm infants (≤34 GA). A comparative study of the semi-elevated and the side-lying position – A pilot study

<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The progress that has been made in neonatology is associated with an increasing number of painful procedures constantly being performed on the neonate. Additionally, prolonged hospitalization of premature neonates in NICUs isolates the family from their child. Parents may state that they do not have any parental feelings and cannot communicate with their newborns. The FCC (Family-Centered Care) initiative responded to emerging reports about the adverse consequences ensuing from the lack of parental access to hospitalized children. The FCC should be understood as care based on partner relations between families and health professionals, which is supposed to lead to health and well-being for both the children and their parents. The FCC should become standard practice in all neonatal intensive care units.</p></abstract>

What should be changed in Polish neonatal units in order to implement family-centered care?

<abstract xmlns="http://www.w3.org/1999/xhtml">

<p><italic>Among the different age groups of children, newborns are most exposed to hospital-acquired bloodstream infection (HA-BS1), especially those who are burdened with additional risk factors, such as low birth weight, immaturity or exposition to medical procedures</italic>.</p>
<p><italic>The aim of this study was to analyze the aetiology of HA-BS1 among children at high risk, including incidence and drug resistance</italic>.</p>
<p><italic>The data was obtained from the PubMed database and included medico/ articles as welI as UNICEF and WHO reports published from 2002 to 2017. The study focused on newborns and older children (under 18 years old) with BS1. The main eligibility criteria, aport from age, were Enterobacteriaceae HA-BS1, and the use of invasive medico/ procedures. It was demonstrated that the main risk factors of infection were age and medico/ procedures. Due to non-specific symptoms, sepsis is difficult to diagnose, a fact which leads to a high mortality rate in newborns</italic>.</p>
<p><italic>The existence of such mufti-drug resistant strains as Extended-Spectrum β-Lactamases (ESBLs) or Carbapenem-Resistant Enterobacteriaceae (CRE) phenotypes is a grave couse for concern</italic>.</p></abstract>

Hospital-acquired <italic>enterobacteriaceae</italic> bloodstream infections in children

<abstract xmlns="http://www.w3.org/1999/xhtml">

<p><italic>Iron is an element whose content in the human organism remains under strict control not only due to its involvement in many life processes but also because of its potential toxicity. The latest studies in iron metabolism, especially the involvement of hepcidin, which is the main regulator of iron homeostasis, broadened our knowledge in many medico/ fields (immunology, nephrology, hematology, gastrology). The present paper is a review of the literature devoted to the importance of hepcidin under selected conditions</italic>.</p></abstract>

The role of hepcidin in regulating iron homeostasis in selected diseases

<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>Hyperbaric oxygen therapy (HBOT), which is a centuries-old treatment, has now increasingly often been used in the pediatrie population. The basie indications for HBOT are well-known disease entities, i.e. carbon monoxide poisoning or decompression sickness. Due to the immunomodulatory properties of hyperbaric oxygen, attempts are made to use HBOT in the treatment of atopie dermatitis or inflammatory bowel diseases. The close cooperation between pediatricians and hyperbaric medicine teams is very important to obtain optimal results. The aim of this article is to present the mechanism of hyperbaric oxygen activity, and its influence on selected disease entities. The paper outlines new perspectives for HBOT in the pediatrie population.</p></abstract>

Hyperbaric oxygenation in pediatrics: indications in the light of evidence –Based medicine

AHEAD OF PRINT

Volume 28 (2024): Issue 1 (February 2024)

Volume 27 (2023): Issue 1 (June 2023)

Volume 26 (2022): Issue 1 (March 2022)

Volume 25 (2021): Issue 4 (December 2021)

Volume 25 (2021): Issue 3 (September 2021)

Volume 25 (2021): Issue 2 (June 2021)

Volume 25 (2021): Issue 1 (March 2021)

Volume 24 (2020): Issue 4 (December 2020)

Volume 24 (2020): Issue 3 (September 2020)

Volume 24 (2020): Issue 2 (June 2020)

Volume 24 (2020): Issue 1 (July 2020)

Volume 23 (2019): Issue 4 (December 2019)

Volume 23 (2019): Issue 3 (September 2019)

Volume 23 (2019): Issue 2 (June 2019)

Volume 23 (2019): Issue 1 (March 2019)

Volume 22 (2018): Issue 4 (December 2018)

Volume 22 (2018): Issue 3 (September 2018)

Volume 22 (2018): Issue 2 (June 2018)

Volume 22 (2018): Issue 1 (March 2018)

Volume 21 (2017): Issue 4 (December 2017)

Volume 21 (2017): Issue 3 (September 2017)

Volume 21 (2017): Issue 2 (June 2017)

Volume 21 (2017): Issue 1 (March 2017)

Journal of Mother and Child

The history of the title Relatively new only by the title, the Journal of Mother and Child (JMC) has a long tradition of being issued for nearly 25 years. The journal is a direct successor of a former periodical: Developmental Period Medicine/Medycyna Wieku Rozwojowego. The change of the journal title from Developmental Period Medicine to Journal of Mother and Child took place on January 01, 2020. The archive papers under the old name can be found at: journals.indexcopernicus.com.  The Institute of Mother and Child, Warsaw, Poland, has been publishing the journal Medycyna Wieku Rozwojowego (ISSN 1428-345X) since 1997. That title stems from another journal: Problemy Medycyny Wieku Rozwojowego (ISSN 0303-2264), issued by the Institute in the years 1972-1990. Since 1998 until the end of 2019, the English language translation: Developmental Period Medicine (e-ISSN 2354-0060) was used on the title page. Since 2020, the quarterly Developmental Period Medicine changed its English-language title to the one being more to the point, to: Journal of Mother and Child (ISSN 2719-6488; e-ISSN 2719-535X).　  Thus, until December 31, 2019, the journal was titled Medycyna Wieku Rozwojowego (ISSN 1428-345X) / Developmental Period Medicine (e-ISSN 2354-0060), and from January 1, 2020 it is published further under the title Journal of Mother and Child/Medycyna Wieku Rozwojowego (ISSN 2719-6488; e-ISSN 2719-535X). In other words, there is an uninterrupted continuation of issuing of the journal from 1997 to the present. Title modifications on the way reflected more and more focused selection of topics of interest and increasing role of English language in medical sciences. With our international readership visibly broadened over the last years and with the solely English-language contents, we intend to abandon the title’s Polish translation (subheading: ‘Medycyna Wieku Rozwojowego’) in the near future.  The former version of this journal: Medycyna Wieku Rozwojowego / Developmental Period Medicine was indexed in PubMed / Medline and as such was entered into other databases. Journal of Mother and Child / Medycyna Wieku Rozwojowego continues to be indexed in PubMed / Medline.  Cooperating societies:  The title is published in association with the Polish Society of Perinatal Medicine and the Polish Society of Inborn Errors of Metabolism.     Aims &amp; Scope  JMC is a peer reviewed, diamond open access journal dedicated to disseminating basic and applied research related to the health of mother and child. The journal’s ambition is to create a platform for presenting original results from all areas of research studies that aim to improve human maternal, fetal, neonatal, and child health, reflecting the connection between clinical and basic science. We at JMC strongly believe that translational medicine should support interdisciplinary collaboration, which usually results in important scientific papers. We accept original research papers, review articles, editorials, short communications and case studies.  JMC‘s scope is based on a holistic approach towards the patient, covering all medical aspects of health of a mother and her child, including such important life sciences areas as origins of disease, modern diagnostic tools, effective up-to-date treatment, long-term health consequences, nutrition, psychology, as well as social and bioethical issues. Most importantly, we focus on the patient throughout all stages of life, from early years, i.e. prenatal and perinatal periods, through early childhood and childhood to adolescence and adulthood (including maternal health). JMC follows a concept of the systems medicine, looking at the human body as part of an integrated whole which incorporates biomolecular, physiological and environmental interactions.  JMC also encourages submissions of papers pertaining to rare diseases which may be a good model for a study on common disorders and thus revealing novel pathomechanisms and conditions.  Journal metrics  Medycyna Wieku Rozwojowego  Cite Score (2020) 0.9Cite Score (2019) 0.8Ministry of Education and Science (Poland) Journal Rating Scale - Medycyna Wieku Rozwojowego – 20 points (2019-2021)SCImago Journal Rank (2021) 0.154SCImago Journal Rank (2020) 0.215SCImago Journal Rank (2019) 0.210h-index 17  Journal review process  Journal of Mother and Child is double-blind peer reviewed journal.  Article processing charges  The journal has no article processing charges (APCs) and article submission charges.  Archiving  Sciendo archives the contents of this journal in Portico - digital long-term preservation service of scholarly books, journals and collections.  Plagiarism Policy  The editorial board is participating in a growing community of Similarity Check System's users in order to ensure that the content published is original and trustworthy. Similarity Check is a medium that allows for comprehensive manuscripts screening, aimed to eliminate plagiarism and provide a high standard and quality peer-review process.  EDITORIAL POLICIES AND ETHICAL STANDARDS 　  The Institute of Mother and Child, Warsaw, Poland, the owner of the Journal of Mother and Child (JMC) / Medycyna Wieku Rozwojowego is committed to upholding standards of ethical behaviour at all stages of the publication process. Editorial Board of the Journal follow closely the industry associations, such as the Committee on Publication Ethics (COPE), International Committee of Medical Journal Editors (ICJME), World Association of Medical Editors (WAME), Council of Science Editors that set standards and provide guidelines for best practices in order to meet these requirements.  Duties and responsibilities of Authors  The Author(s) is obliged to prepare and send the article in accordance with the requirements set out in the Instructions for Authors. Moreover, the Author(s) is obliged to submit editorial complemented by a statement which will be included (signed and scanned author statement and JMC license agreement – in one document JMC License Agreement available at the web page of the Journal): a statement about the originality of the content of the article (work not yet published anywhere), the integrity of the copyrights of others, no conflict of interest or its application, as well as the superior permission to publish an article in the journal. The Author(s) is obliged to participate in peer review process. The Author(s) is obliged to provide retractions or corrections of mistakes, they also should provide a list of references.The Author(s) is responsible for disclosing all financial and personal relationships that might bias or be seen to bias their work.　Authors may, at any time before accepting the article for publication, withdraw the article by submitting a statement in the electronic system of the Editorial Manager.  Reporting standards  The Author(s) reporting results of original research should present an accurate account of the work performed, as well as an objective discussions of its significance. Underlying data should be represented accurately in the manuscript. A paper should contain sufficient detail and references to permit others to replicate the work. Fraudulent or knowingly inaccurate statements constitute unethical behaviour and are unacceptable.  Originality and Plagiarism  The Author(s) should ensure that they have written entirely original works, and if the Author(s) have used the work and/or words of others that this has been appropriately cited or quoted.  Multiple, redundant or concurrent publication  The Autho(s) should not in general publish manuscripts describing essentially the same research in more than one journal or primary publication. Parallel submission of the same manuscript to more than one journal constitutes unethical publishing behaviour and is unacceptable.  Acknowledgement of sources  Proper acknowledgement of the work of others must always be given. The Author(s) should also cite publications that have been influential in determining the nature of the reported work.  Authorship of a manuscript  Authorship should be limited to those who have made a significant contribution to the conception, design, execution, or interpretation of the reported study. All those who have made significant contributions should be listed as co-authors. Where there are others who have participated in certain substantive aspects of the research project, they should be named in an Acknowledgement section.The corresponding author should ensure that all appropriate co-authors (according to the above definition) and no inappropriate co-authors are included in the author list of the manuscript, and that all co-authors have seen and approved the final version of the paper and have agreed to its submission for publication.  Hazards and human or animal subjects  If the work involves chemicals, procedures or equipment that have any unusual hazards inherent in their use, the Author(s) must clearly identify these in the manuscript.  Disclosure and conflicts of interest  All Authors should disclose in their manuscript any financial or other substantive conflict of interest that might be construed to influence the results or their interpretation in the manuscript. All sources of financial support for the project should be disclosed.　  Fundamental errors in published works  When the Author(s) discovers a significant error or inaccuracy in his/her own published work, it is the author’s obligation to promptly notify the journal’s editor or publisher and cooperate with them to either retract the paper or to publish an appropriate erratum.　  Authorship criteria and/or who should be listed as a contributor  In the matter of authorship criteria and/or who should be listed as a contributor, the Institute of Mother and Child, Warsaw, Poland, the owner of the Journal of Mother and Child (JMC) / Medycyna Wieku Rozwojowego respects standards recommended by the Committee on Publication Ethics. Detailed information about these criteria can be found in the COPE Report: publicationethics.org/files/2003pdf12_0.pdf  Duties and responsibilities of Reviewers 　  Articles are selected for publication in double-blind selection system and published in open access system. A Reviewer(s) will provide his/her review using the electronic system on the basis of questions prepared for a specific title. It is also possible for a Reviewer(s) to send individual comments to be published in the article content. All judgments and findings in the peer-review process should be objective. Reviewers should have no conflict of interest (they make an appropriate statement before proceeding to review). When it is a legitimate need, Reviewers should point out relevant published work which is not yet cited, and articles reviewed by them should be treated confidentially prior to their publication.  Contribution to editorial decisions  Peer review assists the Editor in making editorial decisions and, through the editorial communication with the Author, may also assist the author in improving the manuscript.  Promptness  Any invited referee who feels unqualified to review the research reported in a manuscript or knows that its timely review will be impossible, should immediately notify the Editor so that alternative reviewers can be contacted.  Confidentiality  Any manuscripts received for review must be treated as confidential documents. They must not be shown to or discussed with others except if authorized by the Editor.  Standards of objectivity  Reviews should be conducted objectively. Personal criticism of the Author is unacceptable. Referees should express their views clearly with appropriate supporting arguments.  Acknowledgement of sources  Reviewers should identify relevant published work that has not been cited by the Authors. Any statement that an observation, derivation, or argument had been previously reported should be accompanied by the relevant citation. A Reviewer should also call to the editor’s attention any substantial similarity or overlap between the manuscript under consideration and any other published data of which they have personal knowledge.  Disclosure and conflict of interest  Privileged information or ideas obtained through peer review must be kept confidential and not used for personal advantage. Reviewers should not consider evaluating manuscripts in which they have conflicts of interest resulting from competitive, collaborative, or other relationships or connections with any of the Authors, companies, or institutions connected to the submission.  Duties and responsibilities of Editors 　  Editors are responsible for deciding which articles are accepted for publication. Editors act in a balanced, objective and fair way while carrying out their expected duties, without discrimination on the grounds of ethnicity or geographical origin, religious or political beliefs, or sexuality of the authors.Publisher and Editors are always ready to publish corrections, clarifications, withdrawals and apologies, if there is a legitimate need.In the situation when there is a suspicion that an inappropriate research procedure described in the work sent has taken place, the Author(s) is obliged by the editorial office to submit (if not yet submitted) information regarding the approval of the described research procedure by a properly established ethics committee to conduct clinical trials.  Accountability  The Editor of a peer-reviewed journal is responsible for deciding which articles submitted to the journal should be published, and, moreover, is accountable for everything published in the journal. In making these decisions, the Editor may be guided by the policies of the journal’s editorial board, as well as by legal requirements regarding libel, copyright infringement and plagiarism. The Editor may confer with other Editors or Reviewers when making publication decisions. The Editor should maintain the integrity of the academic record, preclude business needs from compromising intellectual and ethical standards, and always be willing to publish corrections, clarifications, retractions and apologies when needed.  Fairness  The Editor should evaluate manuscripts for intellectual content. The Editor will not disclose any information about a manuscript under consideration to anyone other than the Author(s), Reviewers and potential reviewers, and in some instances the editorial board members, as appropriate.  Confidentiality  The Editor and any editorial staff must not disclose any information about submitted manuscript to anyone other than he corresponding Author, Reviewers, potential reviewers, other editorial advisers, and the Publisher, as appropriate.  Disclosure, conflict of interest, and other issues  The Editor will be guided by the industry associations, such as the Committee on Publication Ethics (COPE), International Committee of Medical Journal Editors (ICJME), World Association of Medical Editors (WAME), Council of Science Editors that set standards, recommendations and provide guidelines for best practices in retracting articles: when considering retracting, issuing expressions of concern about, and issuing corrections pertaining to articles that have been published in the Journal of Mother and Child.  Unpublished materials disclosed in a submitted manuscript must not be used in an editor’s own research without the expressed written consent of the Author. Privileged information or ideas obtained through peer review must be kept confidential and not used for personal advantage.  The Editor is committed to ensuring that advertising, reprint or other commercial revenue has no impact or influence on editorial decisions.  The Editor should seek to ensure a fair and appropriate peer review process. Editors should recuse themselves (i.e. should ask a co-editor, associate editor or other member of the editorial board instead to review and consider) from considering manuscripts in which they have conflicts of interest resulting from competitive, collaborative, or other relationships or connections with any of the authors, companies, or (possibly) institutions connected to the papers. Editors should require all contributors to disclose relevant competing interests and publish corrections if competing interests are revealed after publication. If needed, other appropriate action should be taken, such as the publication of a retraction or expression of concern.  Involvement and cooperation in investigations  Editors should guard the integrity of the published record by issuing corrections and retractions when needed and pursuing suspected or alleged research and publication misconduct. Editors should pursue reviewer and editorial misconduct. The Editor should take reasonably responsive measures when ethical complaints have been presented concerning a submitted manuscript or published paper.  Publisher’s confirmation 　  In cases of alleged or proven scientific misconduct, fraudulent publication or plagiarism the Publisher, in close collaboration with the Editors, will take all appropriate measures to clarify the situation and to amend the article in question. This includes the prompt publication of an erratum or, in the most severe cases, the complete retraction of the affected work. 

Journal of Mother and Child

Volume 23 (2019): Issue 2 (June 2019)

Invited review

Risk factors for premature aging in childhood cancer survivors

Current development

Recent progress in human placental transcriptomics

Original article/Praca oryginalna

Behavioural factors as predictors of self-rated health among Polish adolescent girls

The impact of positioning on bottle-feeding in preterm infants (≤34 GA). A comparative study of the semi-elevated and the side-lying position – A pilot study

Review article/Praca poglądowa

What should be changed in Polish neonatal units in order to implement family-centered care?

Hospital-acquired enterobacteriaceae bloodstream infections in children

The role of hepcidin in regulating iron homeostasis in selected diseases

Hyperbaric oxygenation in pediatrics: indications in the light of evidence –Based medicine

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