<abstract xmlns="http://www.w3.org/1999/xhtml">

<sec><h3>Background</h3>
<p>Wellens syndrome is a clinical, biological, and electrocardiographic complex that identifies a subgroup of patients with unstable angina who have an impending risk of myocardial infarction and death, representing an equivalent of ST segment elevation myocardial infarction.</p>
</sec>
<sec><h3>Methods</h3>
<p>We conducted a prospective analysis of 64 consecutive patients, recruited over 2 years, with Wellens syndrome who underwent coronary angiography and we compared them with an age- and sex-matched group of patients with non-ST segment elevation acute coronary syndrome who underwent coronary angiography. The primary endpoints of our study were the rate of cardiovascular rehospitalizations, the rate of ischaemic reccurences, the rate of subsequent or recurrent revascularization, and the rate of mortality at six months from the index event.</p>
</sec>
<sec><h3>Results</h3>
<p>At 6 months, the patients in the control group had a higher rate of cardiovascular rehospitalizations (41.9% vs. 21.9%, p = 0.016). The rate of ischaemic recurrences and the rate of global mortality were similar across the two groups.</p>
</sec>
<sec><h3>Conclusion</h3>
<p>Physiopathologically and angiographically, Wellens syndrome is an abortive form of ST segment elevation myocardial infarction, but electrocardiographically and prognostically, it evolves similarly to a non-ST segment elevation acute coronary syndrome.</p>
</sec>
</abstract>

Background
Wellens syndrome is a clinical, biological, and electrocardiographic complex that identifies a subgroup of patients with unstable angina who have an impending risk of myocardial infarction and death, representing an equivalent of ST segment elevation myocardial infarction.

Methods
We conducted a prospective analysis of 64 consecutive patients, recruited over 2 years, with Wellens syndrome who underwent coronary angiography and we compared them with an age- and sex-matched group of patients with non-ST segment elevation acute coronary syndrome who underwent coronary angiography. The primary endpoints of our study were the rate of cardiovascular rehospitalizations, the rate of ischaemic reccurences, the rate of subsequent or recurrent revascularization, and the rate of mortality at six months from the index event.

Results
At 6 months, the patients in the control group had a higher rate of cardiovascular rehospitalizations (41.9% vs. 21.9%, p = 0.016). The rate of ischaemic recurrences and the rate of global mortality were similar across the two groups.

Conclusion
Physiopathologically and angiographically, Wellens syndrome is an abortive form of ST segment elevation myocardial infarction, but electrocardiographically and prognostically, it evolves similarly to a non-ST segment elevation acute coronary syndrome.

Wellens Syndrome: Single Centre Study and Literature Review

University of Medicine and Pharmacy „Carol Davila”

Romanian Journal of Cardiology

This work is licensed under the Creative Commons Attribution 4.0 International License.

{"article-title":"Wellens Syndrome: Single Centre Study and Literature Review"}

Background
Wellens syndrome is a clinical, biological, and electrocardiographic complex that identifies a subgroup of patients with unstable angina who have an...

Wellens Syndrome: Single Centre Study and Literature Review

Article Category: Original Article

Publié en ligne: 31 déc. 2022

Pages: 203 - 209

DOI: https://doi.org/10.2478/rjc-2022-0036

Mots clés
Wellens syndrome, acute coronary syndrome, ischaemic recurrences, rehospitalization, mortality

© 2022 Anamaria Avram et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Wellens Syndrome: Single Centre Study and Literature Review

Article Category: Original Article

Publié en ligne: 31 déc. 2022

Pages: 203 - 209

DOI: https://doi.org/10.2478/rjc-2022-0036

Mots clésWellens syndrome, acute coronary syndrome, ischaemic recurrences, rehospitalization, mortality

© 2022 Anamaria Avram et al., published by Sciendo

This work is licensed under the Creative Commons Attribution 4.0 International License.

Mots clés
Wellens syndrome, acute coronary syndrome, ischaemic recurrences, rehospitalization, mortality