Utility of urinary markers in the assessment of renal dysfunction in familial glomerulonephritis in Dobermann dogs
, , , et | 14 févr. 2020
À propos de cet article
Publié en ligne: 14 févr. 2020
Pages: 181 - 186
Reçu: 08 mai 2019
Accepté: 04 févr. 2020
DOI: https://doi.org/10.2478/jvetres-2020-0012
Mots clés
© 2020 D. Winiarczyk et al. published by Sciendo
This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Concentration of urinary markers in sick Dobermann dogs divided into subgroups (expressed as mean and range)
| Variable | Subgroup A (n – 5) | Subgroup B (n – 5) |
|---|---|---|
| uRBP/uCr (mg/g) | 15.8 (2.6–ALD)* | 0.38 (0.27–0.43) |
| uTHP/uCr (mg/g) | 0.093 (0–0.093) | 1.52 (0.39–3.7)* |
| uIgG/uCr (mg/g) | 742.77 (34.02–2410.81)* | 50.5 (0–85.17) |
Results for blood biochemical parameters in sick Dobermann dogs and healthy dogs (expressed as mean and range)
| Variable (reference range) | Dobermann dogs (n = 10) Mean (range) | Healthy dogs (n = 12) Mean (range) |
|---|---|---|
| Alanine transferase (u/L) (3–50) | 43 (35–49) | 47 (21–101) |
| Aspartate aminotransferase (u/L) (1–37) | 18 (24–38) | 28 (18–46) |
| Total bilirubin (mg/dL) (≤ 0.60) | 0.36 (0.27–0.47) | 0.2 (0.1–0.5) |
| Urea (mg/dL) (20.0–45.0) | 35.9 (24.6–36.6) | 37.7 (27.5–59.7) |
| Creatinine (μmol/L) (88–150) | 114.9 (79.6–141.4) | 106.1 (53–150.3) |
| Alkaline phosphatase (u/L) (20–155) | 137 (98–150) | 122 (110–143) |
| Glucose (mg/dL) (70–120) | 98 (80–118) | 117.2 (66–136) |
| Albumin (g/dL) (3.30–5.60) | 3.54 (3.34–3.80) | 3.7 (3.3–4.5) |
| Total protein (g/dL) (5.50–7.00) | 6.26 (5.23–6.90) | 6.7 (2.2–8.6) |
| Amylase (u/L) (388–1800) | 595 (422–743) | 602 (498–703) |
| Gamma glutamylotransferase (u/L) (5–25) | 18 (12–24) | 14 (8–23) |
Results for routine urinary parameters of renal function in sick Dobermann dogs and healthy dogs (expressed as mean and range)
| Variable | Dobermann dogs (n = 10) | Healthy dogs (n = 12) |
|---|---|---|
| uCr (mg/dL) | 74.1 (20.0–149.6) | 135.64 (53.91–212.82) |
| Specific gravity | 1.03 (1.02–1.03) | 1.03 |
| UPC | 1.3 (0.5–2.3) | <0.5 |
Concentrations of urinary markers in sick Dobermann dogs and healthy dogs (expressed as mean and range)
| Variable | Doberman Pinscher dogs (n = 10) | Healthy dogs (n = 12) |
|---|---|---|
| uRBP/uCr (mg/g) | 2.82 (0.27–10.3)* | 0.23 (0.08–0.41) |
| uTHP/uCr (mg/g) | 0.7 (0–3.7) | 0.2 (0–0.45) |
| uIgG/uCr (mg/g) | 460.4 (34.02–2410.81)* | 0 |