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The article delves into the potential of probiotics and synbiotics as alternative approaches to preventing and treating dental caries. Probiotics are live, non­­pathogenic microorganisms combined with non ­living substances (prebiotics) that support their growth and activity. Probiotics, including strains of Lactobacilli, Bifidobacterium, Streptococcus, secrete various compounds, such as antimicrobial substances, bacteriocins, and enzymes, which help combat cariogenic bacteria. Research suggests that early administration of probiotics can establish a stable oral ecosystem and decrease the risk of dental caries.

Synbiotics, a combination of probiotics and prebiotics, offer a synergistic approach to promoting oral health. Prebiotics like glucomannan hydrolysate, arabinose, xylose, and xylitol support the growth of beneficial bacteria while hindering the proliferation of cariogenic strains. The use of synbiotics, particularly in children, has shown promise in reducing the incidence of dental caries.

Overall, this review highlights the growing interest in probiotics and synbiotics as potential solutions to addressing the complex issue of dental caries. These alternative methods offer the potential to rebalance the oral microbiota and reduce the prevalence of this widespread oral health problem. Nonetheless, further research is needed to confirm their efficacy and long ­term effects in preventing and treating dental caries.