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Management of a patient with factor X deficiency with FEIBA: a case report

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09 août 2023
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A report on a case of factor X deficiency from Assam Medical College and Hospital indicates that FEIBA prophylaxis may be a useful therapy in settings where plasma-derived factor X concentrate (pdFX) is not available
A report on a case of factor X deficiency from Assam Medical College and Hospital indicates that FEIBA prophylaxis may be a useful therapy in settings where plasma-derived factor X concentrate (pdFX) is not available

Figure 1:

Genetic analysis
Procedure and results of F10 gene testing
Genetic analysis Procedure and results of F10 gene testing

Figure 2.

Timeline overview from first presentation to date
Timeline overview from first presentation to date

Factor assay results

TEST PATIENT VALUE REFERENCE
Factor VIII 173.6% 50-150%
Factor X <1% 50-150%
Fibrinogen 231.5mg/dl 150-450mg/dl
Ristocetin co factor assay 89% 50-175%

Coagulation profile results

TEST PATIENT VALUE REFERENCE
Prothrombin time 52.7s 12.5s
aPTT 84.9s 27.6-42.4s
INR 4.80  
Thrombin time 13.5s 12.0-16.0s