This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.
Nowbar AN, Gitto M, Howard JP, Francis DP, Al-Lamee R. Mortality From Ischemic Heart Disease. Circ Cardiovasc Qual Outcomes. 2019;12(6):e005375. doi: 10.1161/CIRCOUTCOMES.118.005375NowbarANGittoMHowardJPFrancisDPAl-LameeRMortality From Ischemic Heart DiseaseCirc Cardiovasc Qual Outcomes2019126e00537510.1161/CIRCOUTCOMES.118.005375Open DOISearch in Google Scholar
Ahuja KR, Saad AM, Nazir S, et al. Trends in Clinical Characteristics and Outcomes in ST-Elevation Myocardial Infarction Hospitalizations in the United States, 2002–2016. Curr Probl Cardiol. 2022;47(12):101005. doi: 10.1016/j.cpcardiol.2021.101005AhujaKRSaadAMNazirSTrends in Clinical Characteristics and Outcomes in ST-Elevation Myocardial Infarction Hospitalizations in the United States, 2002–2016Curr Probl Cardiol2022471210100510.1016/j.cpcardiol.2021.101005Open DOISearch in Google Scholar
Pascual I, Hernandez-Vaquero D, Almendarez M, et al. Observed and Expected Survival in Men and Women After Suffering a STEMI. J Clin Med. 2020;9(4):1174. doi: 10.3390/jcm9041174.PascualIHernandez-VaqueroDAlmendarezMObserved and Expected Survival in Men and Women After Suffering a STEMIJ Clin Med202094117410.3390/jcm9041174Open DOISearch in Google Scholar
Pedersen F, Butrymovich V, Kelbaek H, et al. Short- and long-term cause of death in patients treated with primary PCI for STEMI. J Am Coll Cardiol. 2014;64(20):2101–2108. doi: 10.1016/j.jacc.2014.08.037PedersenFButrymovichVKelbaekHShort- and long-term cause of death in patients treated with primary PCI for STEMIJ Am Coll Cardiol201464202101210810.1016/j.jacc.2014.08.037Open DOISearch in Google Scholar
Park J, Choi KH, Lee JM, et al. Prognostic Implications of Door-to-Balloon Time and Onset-to-Door Time on Mortality in Patients With ST -Segment-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary Intervention. J Am Heart Assoc. 2019;8(9):e012188. doi: 10.1161/JAHA.119.012188ParkJChoiKHLeeJMPrognostic Implications of Door-to-Balloon Time and Onset-to-Door Time on Mortality in Patients With ST -Segment-Elevation Myocardial Infarction Treated With Primary Percutaneous Coronary InterventionJ Am Heart Assoc201989e01218810.1161/JAHA.119.012188Open DOISearch in Google Scholar
Nallamothu B, Fox KA, Kennelly BM, et al. Relationship of treatment delays and mortality in patients undergoing fibrinolysis and primary percutaneous coronary intervention. The Global Registry of Acute Coronary Events. Heart. 2007;93(12):1552–1555. doi: 10.1136/hrt.2006.112847NallamothuBFoxKAKennellyBMRelationship of treatment delays and mortality in patients undergoing fibrinolysis and primary percutaneous coronary intervention. The Global Registry of Acute Coronary EventsHeart200793121552155510.1136/hrt.2006.112847Open DOISearch in Google Scholar
Ghimire G, Gupta A, Hage FG. Guidelines in review: 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction. J Nucl Cardiol. 2014;21(1):190–191. doi: 10.1007/s12350-013-9808-xGhimireGGuptaAHageFGGuidelines in review: 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial InfarctionJ Nucl Cardiol201421119019110.1007/s12350-013-9808-xOpen DOISearch in Google Scholar
Ibanez B, James S, Agewall S, et al. 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Rev Esp Cardiol (Engl Ed). 2017;70(12):1082. doi: 10.1016/j.rec.2017.11.010IbanezBJamesSAgewallS2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevationRev Esp Cardiol (Engl Ed)20177012108210.1016/j.rec.2017.11.010Open DOISearch in Google Scholar
Fordyce CB, Henry TD, Granger CB. Implementation of Regional ST-Segment Elevation Myocardial Infarction Systems of Care: Successes and Challenges. Interv Cardiol Clin. 2016;5(4):415–425. doi: 10.1016/j.iccl.2016.06.001FordyceCBHenryTDGrangerCBImplementation of Regional ST-Segment Elevation Myocardial Infarction Systems of Care: Successes and ChallengesInterv Cardiol Clin20165441542510.1016/j.iccl.2016.06.001Open DOISearch in Google Scholar
Jollis JG, Al-Khalidi HR, Roettig ML, et al. Impact of Regionalization of ST-Segment-Elevation Myocardial Infarction Care on Treatment Times and Outcomes for Emergency Medical Services-Transported Patients Presenting to Hospitals With Percutaneous Coronary Intervention: Mission: Lifeline Accelerator-2. Circulation. 2018;137(4):376–387. doi: 10.1161/CIRCULATIONAHA.117.032446JollisJGAl-KhalidiHRRoettigMLImpact of Regionalization of ST-Segment-Elevation Myocardial Infarction Care on Treatment Times and Outcomes for Emergency Medical Services-Transported Patients Presenting to Hospitals With Percutaneous Coronary Intervention: Mission: Lifeline Accelerator-2Circulation2018137437638710.1161/CIRCULATIONAHA.117.032446Open DOISearch in Google Scholar
Jollis JG, Al-Khalidi HR, Roettig ML, et al. Regional Systems of Care Demonstration Project: American Heart Association Mission: Lifeline STEMI Systems Accelerator. Circulation. 2016;134(5):365–374. doi: 10.1161/CIRCULATIONAHA.115.019474JollisJGAl-KhalidiHRRoettigMLRegional Systems of Care Demonstration Project: American Heart Association Mission: Lifeline STEMI Systems AcceleratorCirculation2016134536537410.1161/CIRCULATIONAHA.115.019474Open DOISearch in Google Scholar
Tatu-Chitoiu G, Arafat R, Deleanu D, Vinereanu D, Udroiu C, Petris A. Impact of the Romanian national programme for interventional therapy in ST-elevation myocardial infarction. EuroIntervention. 2012;8 Suppl P:P126–132. doi: 10.4244/EIJV8SPA22Tatu-ChitoiuGArafatRDeleanuDVinereanuDUdroiuCPetrisAImpact of the Romanian national programme for interventional therapy in ST-elevation myocardial infarctionEuroIntervention20128Suppl PP12613210.4244/EIJV8SPA22Open DOISearch in Google Scholar
Thygesen K, Alpert JS, Jaffe AS, et al. Fourth Universal Definition of Myocardial Infarction (2018). Glob Heart. 2018;13(4):305–338. doi: 10.1016/j.gheart.2018.08.004ThygesenKAlpertJSJaffeASFourth Universal Definition of Myocardial Infarction (2018)Glob Heart201813430533810.1016/j.gheart.2018.08.004Open DOISearch in Google Scholar
Schulman S, Angeras U, Bergqvist D, et al. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients. J Thromb Haemost. 2010;8(1):202–204. doi: 10.1111/j.1538-7836.2009.03678.xSchulmanSAngerasUBergqvistDDefinition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patientsJ Thromb Haemost20108120220410.1111/j.1538-7836.2009.03678.xOpen DOISearch in Google Scholar
Prasad A, Gersh BJ, Mehran R, et al. Effect of Ischemia Duration and Door-to-Balloon Time on Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction: An Analysis From HORIZONS-AMI Trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction). JACC Cardiovasc Interv. 2015;8(15):1966–1974. doi: 10.1016/j.jcin.2015.08.031PrasadAGershBJMehranREffect of Ischemia Duration and Door-to-Balloon Time on Myocardial Perfusion in ST-Segment Elevation Myocardial Infarction: An Analysis From HORIZONS-AMI Trial (Harmonizing Outcomes with Revascularization and Stents in Acute Myocardial Infarction)JACC Cardiovasc Interv20158151966197410.1016/j.jcin.2015.08.031Open DOISearch in Google Scholar
Garcia-Dorado D, Theroux P, Elizaga J, Galinanes M, Solares J, Riesgo M, et al. Myocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusion. Cardiovasc Res. 1987;21(7):537–544. doi: 10.1093/cvr/21.7.537Garcia-DoradoDTherouxPElizagaJGalinanesMSolaresJRiesgoMMyocardial reperfusion in the pig heart model: infarct size and duration of coronary occlusionCardiovasc Res198721753754410.1093/cvr/21.7.537Open DOISearch in Google Scholar
Reimer KA, Vander Heide RS, Richard VJ. Reperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental models. Am J Cardiol. 1993;72(19):13G–21G. doi: 10.1016/0002-9149(93)90102-iReimerKAVander HeideRSRichardVJReperfusion in acute myocardial infarction: effect of timing and modulating factors in experimental modelsAm J Cardiol1993721913G21G10.1016/0002-9149(93)90102-iOpen DOISearch in Google Scholar
Sardar MR, Dawn Abbott J. Myocardial salvage and mortality in STEMI: A race against ischemic time. Catheter Cardiovasc Interv. 2016;87(7):1201–1202. doi: 10.1002/ccd.26599SardarMRDawn AbbottJMyocardial salvage and mortality in STEMI: A race against ischemic timeCatheter Cardiovasc Interv20168771201120210.1002/ccd.26599Open DOISearch in Google Scholar
Solhpour A, Chang KW, Arain SA, et al. Ischemic time is a better predictor than door-to-balloon time for mortality and infarct size in ST-elevation myocardial infarction. Catheter Cardiovasc Interv. 2016;87(7):1194–1200. doi: 10.1002/ccd.26230SolhpourAChangKWArainSAIschemic time is a better predictor than door-to-balloon time for mortality and infarct size in ST-elevation myocardial infarctionCatheter Cardiovasc Interv20168771194120010.1002/ccd.26230Open DOISearch in Google Scholar
Chandrasekhar J, Marley P, Allada C, et al. Symptom-to-Balloon Time is a Strong Predictor of Adverse Events Following Primary Percutaneous Coronary Intervention: Results From the Australian Capital Territory PCI Registry. Heart Lung Circ. 2017;26(1):41–48. doi: 10.1016/j.hlc.2016.05.114ChandrasekharJMarleyPAlladaCSymptom-to-Balloon Time is a Strong Predictor of Adverse Events Following Primary Percutaneous Coronary Intervention: Results From the Australian Capital Territory PCI RegistryHeart Lung Circ2017261414810.1016/j.hlc.2016.05.114Open DOISearch in Google Scholar
Kim HK, Jeong MH, Ahn Y, et al. Relationship between time to treatment and mortality among patients undergoing primary percutaneous coronary intervention according to Korea Acute Myocardial Infarction Registry. J Cardiol. 2017;69(1):377–382. doi: 10.1016/j.jjcc.2016.09.002KimHKJeongMHAhnYRelationship between time to treatment and mortality among patients undergoing primary percutaneous coronary intervention according to Korea Acute Myocardial Infarction RegistryJ Cardiol201769137738210.1016/j.jjcc.2016.09.002Open DOISearch in Google Scholar
Khowaja S, Ahmed S, Kumar R, et al. Time to think beyond door to balloon time: significance of total ischemic time in STEMI. Egypt Heart J. 2021;73(1):95. doi: 10.1186/s43044-021-00221-1KhowajaSAhmedSKumarRTime to think beyond door to balloon time: significance of total ischemic time in STEMIEgypt Heart J20217319510.1186/s43044-021-00221-1Open DOISearch in Google Scholar
Doddipalli SR, Rajasekhar D, Vanajakshamma V, Sreedhar Naik K. Determinants of total ischemic time in primary percutaneous coronary interventions: A prospective analysis. Indian Heart J. 2018;70(Suppl 3):S275–S279. doi: 10.1016/j.ihj.2018.05.005DoddipalliSRRajasekharDVanajakshammaVSreedhar NaikKDeterminants of total ischemic time in primary percutaneous coronary interventions: A prospective analysisIndian Heart J201870Suppl 3S275S27910.1016/j.ihj.2018.05.005Open DOISearch in Google Scholar
Hedges JR, Feldman HA, Bittner V, et al. Impact of community intervention to reduce patient delay time on use of reperfusion therapy for acute myocardial infarction: rapid early action for coronary treatment (REACT) trial. REACT Study Group. Acad Emerg Med. 2000;7(8):862–872. doi: 10.1111/j.1553-2712.2000.tb02063.xHedgesJRFeldmanHABittnerVImpact of community intervention to reduce patient delay time on use of reperfusion therapy for acute myocardial infarction: rapid early action for coronary treatment (REACT) trial. REACT Study GroupAcad Emerg Med20007886287210.1111/j.1553-2712.2000.tb02063.xOpen DOISearch in Google Scholar
Blohm MB, Hartford M, Karlson BW, Luepker RV, Herlitz J. An evaluation of the results of media and educational campaigns designed to shorten the time taken by patients with acute myocardial infarction to decide to go to hospital. Heart. 1996;76(5):430–434. doi: 10.1136/hrt.76.5.430BlohmMBHartfordMKarlsonBWLuepkerRVHerlitzJAn evaluation of the results of media and educational campaigns designed to shorten the time taken by patients with acute myocardial infarction to decide to go to hospitalHeart199676543043410.1136/hrt.76.5.430Open DOISearch in Google Scholar
Regueiro A, Rosas A, Kaifoszova Z, et al. Impact of the “ACT NOW. SAVE A LIFE” public awareness campaign on the performance of a European STEMI network. Int J Cardiol. 2015;197:110–112. doi: 10.1016/j.ijcard.2015.06.040RegueiroARosasAKaifoszovaZImpact of the “ACT NOW. SAVE A LIFE” public awareness campaign on the performance of a European STEMI networkInt J Cardiol201519711011210.1016/j.ijcard.2015.06.040Open DOISearch in Google Scholar
Terkelsen CJ, Sorensen JT, Maeng M, et al. System delay and mortality among patients with STEMI treated with primary percutaneous coronary intervention. JAMA. 2010;304(7):763–771. doi: 10.1001/jama.2010.1139TerkelsenCJSorensenJTMaengMSystem delay and mortality among patients with STEMI treated with primary percutaneous coronary interventionJAMA2010304776377110.1001/jama.2010.1139Open DOISearch in Google Scholar
Chakrabarti A, Krumholz HM, Wang Y, Rumsfeld JS, Nallamothu BK, National Cardiovascular Data R. Time-to-reperfusion in patients undergoing interhospital transfer for primary percutaneous coronary intervention in the U.S: an analysis of 2005 and 2006 data from the National Cardiovascular Data Registry. JACC. 2008;51(25):2442–2443. doi: 10.1016/j.jacc.2008.02.071ChakrabartiAKrumholzHMWangYRumsfeldJSNallamothuBKNational Cardiovascular Data RTime-to-reperfusion in patients undergoing interhospital transfer for primary percutaneous coronary intervention in the U.S: an analysis of 2005 and 2006 data from the National Cardiovascular Data RegistryJACC200851252442244310.1016/j.jacc.2008.02.071Open DOISearch in Google Scholar
Nallamothu BK, Bates ER, Herrin J, et al. Times to treatment in transfer patients undergoing primary percutaneous coronary intervention in the United States: National Registry of Myocardial Infarction (NRMI)-3/4 analysis. Circulation. 2005;111(6):761–767. doi: 10.1161/01.CIR.0000155258.44268.F8NallamothuBKBatesERHerrinJTimes to treatment in transfer patients undergoing primary percutaneous coronary intervention in the United States: National Registry of Myocardial Infarction (NRMI)-3/4 analysisCirculation2005111676176710.1161/01.CIR.0000155258.44268.F8Open DOISearch in Google Scholar
Ikemura N, Kohsaka S, Ueda I, Maekawa Y, Fukuda K. Factors associated with delay in door-to-balloon time in Japan: a report from contemporary multicenter PCI registry. JACC. 2016;67(S13):652. doi: 10.1016/S0735-1097(16)30653-2IkemuraNKohsakaSUedaIMaekawaYFukudaKFactors associated with delay in door-to-balloon time in Japan: a report from contemporary multicenter PCI registryJACC201667S1365210.1016/S0735-1097(16)30653-2Open DOISearch in Google Scholar
Bagai A, Jollis JG, Dauerman HL, et al. Emergency department bypass for ST-Segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: a report from the American Heart Association Mission: Lifeline program. Circulation. 2013;128(4):352–359. doi: 10.1161/CIRCULATIONAHA.113.002339BagaiAJollisJGDauermanHLEmergency department bypass for ST-Segment-elevation myocardial infarction patients identified with a prehospital electrocardiogram: a report from the American Heart Association Mission: Lifeline programCirculation2013128435235910.1161/CIRCULATIONAHA.113.002339Open DOISearch in Google Scholar
Pinto DS, Frederick PD, Chakrabarti AK, et al. Benefit of transferring ST-segment-elevation myocardial infarction patients for percutaneous coronary intervention compared with administration of onsite fibrinolytic declines as delays increase. Circulation. 2011;124(23):2512–2521. doi: 10.1161/CIRCULATIONAHA.111.018549PintoDSFrederickPDChakrabartiAKBenefit of transferring ST-segment-elevation myocardial infarction patients for percutaneous coronary intervention compared with administration of onsite fibrinolytic declines as delays increaseCirculation2011124232512252110.1161/CIRCULATIONAHA.111.018549Open DOISearch in Google Scholar
Boersma E. Primary Coronary Angioplasty vs. Thrombolysis G. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. Eur Heart J. 2006;27(7):779–788. doi: 10.1093/eurheartj/ehi810BoersmaEPrimary Coronary Angioplasty vs. Thrombolysis G. Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patientsEur Heart J200627777978810.1093/eurheartj/ehi810Open DOISearch in Google Scholar
Larson DM, Duval S, Sharkey SW, et al. Safety and efficacy of a pharmaco-invasive reperfusion strategy in rural ST-elevation myocardial infarction patients with expected delays due to long-distance transfers. Eur Heart J. 2012;33(10):1232–1240. doi: 10.1093/eurheartj/ehr403LarsonDMDuvalSSharkeySWSafety and efficacy of a pharmaco-invasive reperfusion strategy in rural ST-elevation myocardial infarction patients with expected delays due to long-distance transfersEur Heart J201233101232124010.1093/eurheartj/ehr403Open DOISearch in Google Scholar
Larson DM, McKavanagh P, Henry TD, Cantor WJ. Reperfusion Options for ST Elevation Myocardial Infarction Patients with Expected Delays to Percutaneous Coronary Intervention. Interv Cardiol Clin. 2016;5(4):439–450. doi: 10.1016/j.iccl.2016.06.004LarsonDMMcKavanaghPHenryTDCantorWJReperfusion Options for ST Elevation Myocardial Infarction Patients with Expected Delays to Percutaneous Coronary InterventionInterv Cardiol Clin20165443945010.1016/j.iccl.2016.06.004Open DOISearch in Google Scholar