<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>The role of cardiac biomarkers in diagnosing acute myocardial infarction is undoubted. In the 2020 guidelines of the European Society of Cardiology, the measurement of cardiac peptides to gain prognostic information has a class IIa indication in all patients with ACS. In emergency care, ruling out a non-ST elevation myocardial infarction requires documentation of normal levels of cardiac biomarkers, which remain stable or have very small variations within several hours. This review aims to summarize the current knowledge and recent progresses in the field of cardiac biomarker discovery, from their routine use in emergency rooms to their prognostic roles in modern risk assessment tools. Integrated approaches combining cardiac troponin with other biomarkers of ventricular dysfunction or inflammation, or with modern cardiac imaging in emergency care are also presented, as well as the role of modern algorithms for serial troponin measurement in the modern management of emergency departments.</p>
</abstract>

The role of cardiac biomarkers in diagnosing acute myocardial infarction is undoubted. In the 2020 guidelines of the European Society of Cardiology, the measurement of cardiac peptides to gain prognostic information has a class IIa indication in all patients with ACS. In emergency care, ruling out a non-ST elevation myocardial infarction requires documentation of normal levels of cardiac biomarkers, which remain stable or have very small variations within several hours. This review aims to summarize the current knowledge and recent progresses in the field of cardiac biomarker discovery, from their routine use in emergency rooms to their prognostic roles in modern risk assessment tools. Integrated approaches combining cardiac troponin with other biomarkers of ventricular dysfunction or inflammation, or with modern cardiac imaging in emergency care are also presented, as well as the role of modern algorithms for serial troponin measurement in the modern management of emergency departments.

Cardiac Biomarkers in 2022 – a Vital Tool for Emergency Care

“George Emil Palade” University of Medicine, Pharmacy, Science and Technology

Department of Anesthesiology and Critical Care

Journal of Cardiovascular Emergencies

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

{"article-title":"Cardiac Biomarkers in 2022 \u2013 a Vital Tool for Emergency Care"}

The role of cardiac biomarkers in diagnosing acute myocardial infarction is undoubted. In the 2020 guidelines of the European Society of Cardiology, the...

Cardiac Biomarkers in 2022 – a Vital Tool for Emergency Care

Publié en ligne: 27 janv. 2023

Pages: 43 - 53

Reçu: 20 sept. 2022

Accepté: 27 sept. 2022

DOI: https://doi.org/10.2478/jce-2022-0012

Mots clés
cardiac biomarkers, emergency cardiovascular care, acute coronary syndromes

© 2022 Theodora Benedek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Cardiac Biomarkers in 2022 – a Vital Tool for Emergency Care

Publié en ligne: 27 janv. 2023

Pages: 43 - 53

Reçu: 20 sept. 2022

Accepté: 27 sept. 2022

DOI: https://doi.org/10.2478/jce-2022-0012

Mots cléscardiac biomarkers, emergency cardiovascular care, acute coronary syndromes

© 2022 Theodora Benedek et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
cardiac biomarkers, emergency cardiovascular care, acute coronary syndromes