Effect of Gender on the Radiation Sensitivity of Murine Blood Cells

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| 18 janv. 2022

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Cells & Other Parameters	Male		Female		P-value⁴
Cells & Other Parameters	AVE²	n³	AVE²	n³	P-value⁴
WBCs (x 10³/µl)	7.6 ± 2.5	42	7.4± 2.1	41	0.68
RBCs (x 10⁶/µl)	7.9 ± 0.5	41	7.9 ± 0.6	41	0.87
Hemoglobin (g/dl)	13.5 ± 0.6	41	13.7 ± 0.5	41	0.2
Hematocrit (%)	44.2 ± 2.4	41	44 ± 1.9	41	0.64
Platelets (x 10³/µl)⁵	1114 ± 196	41	966 ± 202	41	0.0012
Neutrophils (/µl)	1848 ± 1416	41	1493 ± 544	42	0.13
Lymphocytes (/µl)	5291 ± 1569	42	5561 ± 1655	42	0.44
Monocytes (/µl)	154 ± 127	42	145 ± 164	42	0.76
Eosinophils (/µl)	127 ± 85	42	130 ± 87	42	0.86
Basophils (/µl)	53 ± 71	42	55 ± 68	42	0.89
Granulocytes (/µl)⁶	2029 ± 1443	41	1678 ± 594	42	0.15

Gender	Dose (Gy)	Time Post-IR	AVE	SD	n
Male	0	1	1108	322	11
Female	0	1	1020	228	10
Male	0.5	1	1082	151	10
Female	0.5	1	1094	98	10
Male	1	1	1091	192	9
Female	1	1	1011	75	9
Male	2	1	1123	110	8
Female	2	1	1007	158	10
Male	0	4	1061	204	11
Female	0	4	905	224	11
Male	0.5	4	1000	217	10
Female	0.5	4	1092	207	9
Male	1	4	1030	204	10
Female	1	4	1088	240	8
Male	2	4	1072	198	10
Female	2	4	1034	99	10
Male	0	11	1096	212	10
Female	0	11	962	204	10
Male	0.5	11	685	279	10
Female	0.5	11	780	141	9
Male	1	11	418	133	9
Female	1	11	385	72	9
Male	2	11	334	105	8
Female	2	11	248	61	10
Male	0	16	1116	245	10
Female	0	16	1028	65	9
Male	0.5	16	1185	101	5
Female	0.5	16	1016	57	9
Male	1	16	1163	102	10
Female	1	16	834	95	10
Male	2	16	871	154	10
Female	2	16	470	159	9