<abstract xmlns="http://www.w3.org/1999/xhtml"><p>Bacterial meningitis is a devastating worldwide disease. Half of the survivors of meningitis remain with permanent neurological sequelae. The pathogenesis of meningitis is based on a complex host-pathogen interaction. <italic>Streptococcus pneumoniae</italic> is a life-threatening neuroinvasive pathogen that asymptomatically colonizes the upper respiratory tract. Adherence of pneumococci to the host epithelium is a prerequisite in the onset of streptococcal infections; such adherence is favored by the formation of bacterial pili. In this article, we will describe the pneumococcal pili and its contribution to the onset of meningitis.</p></abstract>

Bacterial meningitis is a devastating worldwide disease. Half of the survivors of meningitis remain with permanent neurological sequelae. The pathogenesis of meningitis is based on a complex host-pathogen interaction. Streptococcus pneumoniae is a life-threatening neuroinvasive pathogen that asymptomatically colonizes the upper respiratory tract. Adherence of pneumococci to the host epithelium is a prerequisite in the onset of streptococcal infections; such adherence is favored by the formation of bacterial pili. In this article, we will describe the pneumococcal pili and its contribution to the onset of meningitis.

Contribution of Pili of <italic>S. Pneumoniae</italic> in the Onset of Meningitis

Laboratory of Biomedical Microbiology and Immunology

University of Veterinary Medicine and Pharmacy

Institute of Neuroimmunology of the Slovak Academy of Science

Folia Veterinaria

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Contribution of Pili of  in the Onset of Meningitis

Bacterial meningitis is a devastating worldwide disease. Half of the survivors of meningitis remain with permanent neurological sequelae. The pathogenesis of...

Contribution of Pili of S. Pneumoniae in the Onset of Meningitis

Publié en ligne: 11 avr. 2018

Pages: 67 - 72

Reçu: 04 déc. 2017

Accepté: 08 févr. 2018

DOI: https://doi.org/10.2478/fv-2018-0010

Mots clés
meningitis, pili,

© 2018 Jiménez-Munguía, I. et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Contribution of Pili of S. Pneumoniae in the Onset of Meningitis

Publié en ligne: 11 avr. 2018

Pages: 67 - 72

Reçu: 04 déc. 2017

Accepté: 08 févr. 2018

DOI: https://doi.org/10.2478/fv-2018-0010

Mots clésmeningitis, pili,

© 2018 Jiménez-Munguía, I. et al., published by De Gruyter Open

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License.

Mots clés
meningitis, pili,