<abstract xmlns="http://www.w3.org/1999/xhtml">

<p>This paper presents the effect of selected alcohols on the fluidity of liposome membranes obtained in sonication of DPPC lecithin. Using the EPR technique, the duality of propanol, n-butanol and pentanol on the behaviour of the aqueous dispersion of liposomes was demonstrated. It was shown that after exceeding a certain concentration, these alcohols initiate dispersion foaming, leading to phase separation: liposome dispersion - lipid foam. The influence of the shape of the molecule and the length of hydrocarbon chains on the effectiveness of destabilisation of the structure of lipid membranes was indicated.</p>
</abstract>

This paper presents the effect of selected alcohols on the fluidity of liposome membranes obtained in sonication of DPPC lecithin. Using the EPR technique, the duality of propanol, n-butanol and pentanol on the behaviour of the aqueous dispersion of liposomes was demonstrated. It was shown that after exceeding a certain concentration, these alcohols initiate dispersion foaming, leading to phase separation: liposome dispersion - lipid foam. The influence of the shape of the molecule and the length of hydrocarbon chains on the effectiveness of destabilisation of the structure of lipid membranes was indicated.

The Impact of Propanol, N-Butanol and Pentanol on Aqueous Dispersions of Sonicated Liposomes. EPR Study

Ecological Chemistry and Engineering S

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

This paper presents the effect of selected alcohols on the fluidity of liposome membranes obtained in sonication of DPPC lecithin. Using the EPR technique, the...

The Impact of Propanol, N-Butanol and Pentanol on Aqueous Dispersions of Sonicated Liposomes. EPR Study

Publié en ligne: 14 janv. 2023

Pages: 565 - 579

DOI: https://doi.org/10.2478/eces-2022-0032

Mots clés
alcohols, liposomes, Electron Paramagnetic Resonance (EPR), DPPC lecithin

© 2022 Agnieszka Bartnikowska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

The Impact of Propanol, N-Butanol and Pentanol on Aqueous Dispersions of Sonicated Liposomes. EPR Study

Publié en ligne: 14 janv. 2023

Pages: 565 - 579

DOI: https://doi.org/10.2478/eces-2022-0032

Mots clésalcohols, liposomes, Electron Paramagnetic Resonance (EPR), DPPC lecithin

© 2022 Agnieszka Bartnikowska et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
alcohols, liposomes, Electron Paramagnetic Resonance (EPR), DPPC lecithin