Accès libre

Dual effect of the GHRL gene variant in the molecular pathogenesis of obesity

 et    | 27 juil. 2021
À propos de cet article

Citez

Vandevijvere S, Chow CC, Hall KD, Umali E, Swinburn BA. Increased food energy supply as a major driver of the obesity epidemic: A global analysis. Bull World Health Organ. 2015; 93(7): 446-456.Vandevijvere S Chow CC Hall KD Umali E Swinburn BA Increased food energy supply as a major driver of the obesity epidemic: A global analysis Bull World Health Organ 2015 93 7 446 45610.2471/BLT.14.150565449081626170502Search in Google Scholar

Van Gaal LF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006; 444 (7121): 875-880.Van Gaal LF Mertens IL De Block CE Mechanisms linking obesity with cardiovascular disease Nature 2006 444 7121 875 88010.1038/nature0548717167476Search in Google Scholar

Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet. 1997; 27(4): 325-351.Maes HH Neale MC Eaves LJ Genetic and environmental factors in relative body weight and human adiposity Behav Genet 1997 27 4 325 35110.1023/A:1025635913927Search in Google Scholar

Pérusse L, Bouchard C. Gene-diet interactions in obesity. Am J Clin Nutr. 2000; 72(5 Suppl): 1285S-1290S.Pérusse L Bouchard C Gene-diet interactions in obesity Am J Clin Nutr 2000 72 5 Suppl 1285S 129010.1093/ajcn/72.5.1285s11063470Search in Google Scholar

Bell CG, Walley AJ, Froguel P. The genetics of human obesity. Nat Rev Genet. 2005; 6(3): 221-234.Bell CG Walley AJ Froguel P The genetics of human obesity Nat Rev Genet 2005 6 3 221 23410.1038/nrg155615703762Search in Google Scholar

Bienertova-Vasku J, Bienert P, Sablikova L, Slovackova L, Forejt M, Piskackova Z, et al. Effect of ID ACE gene polymorphism on dietary composition and obesity-related anthropometric parameters in the Czech adult population. Genes Nutr. 2009; 4(30): 207-213.Bienertova-Vasku J Bienert P Sablikova L Slovackova L Forejt M Piskackova Z et al Effect of ID ACE gene polymorphism on dietary composition and obesity-related anthropometric parameters in the Czech adult population Genes Nutr 2009 4 30 207 21310.1007/s12263-009-0130-9274574619609587Search in Google Scholar

van den Bree MB, Eaves LJ, Dwyer JT. Genetic and environmental influences on eating patterns of twins aged >/=50 y. Am J Clin Nutr. 1999; 70(4): 456-465van den Bree MB Eaves LJ Dwyer JT Genetic and environmental influences on eating patterns of twins aged >/=50 y Am J Clin Nutr 1999 70 4 456 46510.1093/ajcn/70.4.45610500013Search in Google Scholar

Maes HH, Neale MC, Eaves LJ. Genetic and environmental factors in relative body weight and human adiposity. Behav Genet. 1997; 27(4): 325-351.Maes HH Neale MC Eaves LJ Genetic and environmental factors in relative body weight and human adiposity Behav Genet 1997 27 4 325 35110.1023/A:1025635913927Search in Google Scholar

Kourlaba G, Pitsiladis YP, Lagou V, Grammatikaki E, Moran CN, Kondaki K, et al. Interaction efects between total energy and macronutrient intakes and angio-tensin-converting enzyme 1 (ACE) I/D polymorphism on adiposity-related phenotypes in toddlers and preschoolers: the growth, exercise and nutrition epidemiological study in preschoolers: The GENESIS study. [corrected] Br J Nutr. 2008; 100(6): 1333-1340.Kourlaba G Pitsiladis YP Lagou V Grammatikaki E Moran CN Kondaki K et al Interaction efects between total energy and macronutrient intakes and angio-tensin-converting enzyme 1 (ACE) I/D polymorphism on adiposity-related phenotypes in toddlers and preschoolers: the growth, exercise and nutrition epidemiological study in preschoolers: The GENESIS study [corrected] Br J Nutr 2008 100 6 1333 134010.1017/S000711450898875918479585Search in Google Scholar

Rankinen T, Zuberi A, Chagnon YC, Weisnagel SJ, Argyropoulos G, Walts B, et al. The human obesity gene map: The 2005 update. Obesity (Silver Spring). 2006; 14(4): 529-644.Rankinen T Zuberi A Chagnon YC Weisnagel SJ Argyropoulos G Walts B et al The human obesity gene map: The 2005 update Obesity (Silver Spring) 2006 14 4 529 64410.1038/oby.2006.7116741264Search in Google Scholar

Snyder EE, Walts B, Pérusse L, Chagnon YC, Weisnagel SJ, Rankinen T, et al. The human obesity gene map: The 2003 update. Obes Res. 2004; 12(3): 369-439.Snyder EE Walts B Pérusse L, Chagnon YC Weisnagel SJ Rankinen T et al The human obesity gene map: The 2003 update Obes Res 2004 12 3 369 43910.1038/oby.2004.4715044658Search in Google Scholar

Ghalandari H, Hosseini-Esfahani F, Mirmiran P. The association of polymorphisms in leptin/leptin receptor genes and ghrelin/ghrelin receptor genes with overweight/obesity and the related metabolic disturbances: A review. Int J Endocrinol Metab. 2015; 13(3): e19073.Ghalandari H Hosseini-Esfahani F Mirmiran P The association of polymorphisms in leptin/leptin receptor genes and ghrelin/ghrelin receptor genes with overweight/obesity and the related metabolic disturbances: A review Int J Endocrinol Metab 2015 13 3 e1907310.5812/ijem.19073v2458442026425125Search in Google Scholar

Fischer H, Heidemann T, Hengst K, Domschke W, Konturek JW. Disturbed gastric motility and pancreatic hormone release in diabetes mellitus. J Physiol Pharmacol. 1998; 49(4): 529-541.Fischer H Heidemann T Hengst K Domschke W Konturek JW Disturbed gastric motility and pancreatic hormone release in diabetes mellitus J Physiol Pharmacol 1998 49 4 529 541Search in Google Scholar

Korbonits M, Goldstone AP, Gueorguiev M, Grossman AB. Ghrelin-a hormone with multiple functions. Front Neuroendocrinol. 2004; 25(1): 27-68.Korbonits M Goldstone AP Gueorguiev M Grossman AB Ghrelin-a hormone with multiple functions Front Neuroendocrinol 2004 25 1 27 6810.1016/j.yfrne.2004.03.00215183037Search in Google Scholar

Zhang JV, Ren PG, Avsian-Kretchmer O, Luo CW, Rauch R, Klein C, et al. Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin’s effects on food intake. Science. 2005; 310(5750): 996-999.Zhang JV Ren PG Avsian-Kretchmer O Luo CW Rauch R Klein C et al Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin’s effects on food intake Science 2005 310 5750 996 99910.1126/science.111725516284174Search in Google Scholar

Murdolo G, Lucidi P, Di Loreto C, Parlanti N, De Cicco A, Fatone C, et al. Insulin is required for prandial ghrelin suppression in humans. Diabetes. 2003; 52(12): 2923-2927.Murdolo G Lucidi P Di Loreto C Parlanti N De Cicco A Fatone C et al Insulin is required for prandial ghrelin suppression in humans Diabetes 2003 52 12 2923 292710.2337/diabetes.52.12.292314633852Search in Google Scholar

Delhanty PJ, van der Lely AJ. Ghrelin and glucose homeostasis. Peptides. 2003; 32(11): 2309-2318.Delhanty PJ van der Lely AJ Ghrelin and glucose homeostasis Peptides 2003 32 11 2309 231810.1016/j.peptides.2011.03.00121396419Search in Google Scholar

Tschop M, Weyer C, Tataranni PA, Devanarayan V, Ravussin E, Heiman ML. Circulating ghrelin levels are decreased in human obesity. Diabetes. 2001; 50(4): 707-709.Tschop M Weyer C Tataranni PA Devanarayan V Ravussin E Heiman ML Circulating ghrelin levels are decreased in human obesity Diabetes 2001 50 4 707 70910.2337/diabetes.50.4.70711289032Search in Google Scholar

Shiiya T, Nakazato M, Mizuta M, Date Y, Mondal MS, Tanaka M, et al. Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion. J Clin Endocrinol Metab. 2002; 87(1): 240-244.Shiiya T Nakazato M Mizuta M Date Y Mondal MS Tanaka M et al Plasma ghrelin levels in lean and obese humans and the effect of glucose on ghrelin secretion J Clin Endocrinol Metab 2002 87 1 240 24410.1210/jcem.87.1.812911788653Search in Google Scholar

Poykko SM, Kellokoski E, Horkko S, Kauma H, Kesaniemi YA, Ukkola O. Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes. Diabetes. 2003; 52(10): 2546-2553.Poykko SM Kellokoski E Horkko S Kauma H Kesaniemi YA Ukkola O Low plasma ghrelin is associated with insulin resistance, hypertension, and the prevalence of type 2 diabetes Diabetes 2003 52 10 2546 255310.2337/diabetes.52.10.254614514639Search in Google Scholar

Miraglia del Giudice E, Santoro N, Cirillo G, Raimondo P, Grandone A, D’Aniello A, et al. Molecular screening of the ghrelin gene in Italian obese children: The Leu72Met variant is associated with an earlier onset of obesity. Int J Obes Relat Metab Disord. 2004; 28(3): 447-450.Miraglia del Giudice E Santoro N Cirillo G Raimondo P Grandone A D’Aniello A et al Molecular screening of the ghrelin gene in Italian obese children: The Leu72Met variant is associated with an earlier onset of obesity Int J Obes Relat Metab Disord 2004 28 3 447 45010.1038/sj.ijo.080257214724664Search in Google Scholar

Kuzuya M, Ando F, Iguchi A, Shimokata H. Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort. Int J Obes (Lond). 2006; 30(11): 1609-1614.Kuzuya M Ando F Iguchi A Shimokata H Preproghrelin Leu72Met variant contributes to overweight in middle-aged men of a Japanese large cohort Int J Obes (Lond) 2006 30 11 1609 161410.1038/sj.ijo.080329616865101Search in Google Scholar

Larsen LH, Gjesing AP, Sørensen TI, Hamid YH, Echwald SM, Toubro S, et al. Mutation analysis of the preproghrelin gene: No association with obesity and type 2 diabetes. Clin Biochem. 2005; 38(5): 420-424.Larsen LH Gjesing AP Sørensen TI, Hamid YH Echwald SM Toubro S et al Mutation analysis of the preproghrelin gene: No association with obesity and type 2 diabetes Clin Biochem 2005 38 5 420 42410.1016/j.clinbiochem.2005.01.00815820771Search in Google Scholar

Zhang S, Zhai G, Zhang J, Zhou J, Chen C. Ghrelin and obestatin plasma levels and ghrelin/obestatin prepropeptide gene polymorphisms in small for gestational age infants. J Int Med Res. 2014; 42(6): 1232-1242.Zhang S Zhai G Zhang J Zhou J Chen C Ghrelin and obestatin plasma levels and ghrelin/obestatin prepropeptide gene polymorphisms in small for gestational age infants J Int Med Res 2014 42 6 1232 124210.1177/030006051453352525223427Search in Google Scholar

Ergoren MC, Soyler G, Sah H, Becer E. Investigation of potential genomic biomarkers for obesity and personalized medicine. Int J Biol Macromol. 2019; 122: 493-498.Ergoren MC Soyler G Sah H Becer E Investigation of potential genomic biomarkers for obesity and personalized medicine Int J Biol Macromol 2019 122 493 49810.1016/j.ijbiomac.2018.10.05930416093Search in Google Scholar

Rahman M, Berenson AB. Accuracy of current body mass index obesity classification for white, black, and Hispanic reproductive-age women. Obst Gynecol. 2010; 115(5): 982-988.Rahman M Berenson AB Accuracy of current body mass index obesity classification for white, black, and Hispanic reproductive-age women Obst Gynecol 2010 115 5 982 98810.1097/AOG.0b013e3181da9423288659620410772Search in Google Scholar

Morimoto A, Tatsumi Y, Soyano F, Miyamatsu N, Sonoda N, Godai K, et al. Increase in homeostasis model assessment of insulin resistance (HOMA-IR) had a strong impact on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion: The Saku study. PloS One. 2014; 9(8): e105827.Morimoto A Tatsumi Y Soyano F Miyamatsu N Sonoda N Godai K et al Increase in homeostasis model assessment of insulin resistance (HOMA-IR) had a strong impact on the development of type 2 diabetes in Japanese individuals with impaired insulin secretion: The Saku study PloS One 2014 9 8 e10582710.1371/journal.pone.0105827414834225166121Search in Google Scholar

Wang K, Wang L, Zhao Y, Shi Y, Wang L, Chen ZJ. No association of the Arg51Gln and Leu72Met polymorphisms of the ghrelin gene and polycystic ovary syndrome. Hum Reprod. 2010; 24(2): 485-490.Wang K Wang L Zhao Y Shi Y Wang L Chen ZJ No association of the Arg51Gln and Leu72Met polymorphisms of the ghrelin gene and polycystic ovary syndrome Hum Reprod 2010 24 2 485 49010.1093/humrep/den43019049992Search in Google Scholar

Ensembl Genome Browser [Internet]. Available from http://www.ensembl.org/Homo_sapiens/Variation/Population?db=core;r=3:10289335-10290335;v=rs34911341;vdb=variation;vf=616156581.Ensembl Genome Browser [Internet] Available from http://www.ensembl.org/Homo_sapiens/Variation/Population?db=core;r=3:1028933510290335;v=rs34911341;vdb=variation;vf=616156581Search in Google Scholar

Northern Cyprus State Planning Organization, 2006. Available from: http://nufussayimi.devplan.org/Kesin-sonuc-index_en.htmlNorthern Cyprus State Planning Organization 2006 Available from http://nufussayimi.devplan.org/Kesin-sonuc-index_en.htmlSearch in Google Scholar

Li P, Tiwari HK, Lin WY, Allison AD, Chung WK, Leibel RL, et al. Genetic association analysis of 30 genes related to obesity in a European American population. Int J Obes. 2014; 38(5): 724-729.Li P Tiwari HK Lin WY Allison AD Chung WK Leibel RL et al Genetic association analysis of 30 genes related to obesity in a European American population Int J Obes 2014 38 5 724 72910.1038/ijo.2013.140390901823900445Search in Google Scholar

Becer E, Mehmetcik G, Bareke H, Serakinci N. Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects. Gene. 2003; 529(1): 16-20.Becer E Mehmetcik G Bareke H Serakinci N Association of leptin receptor gene Q223R polymorphism on lipid profiles in comparison study between obese and non-obese subjects Gene 2003 529 1 16 2010.1016/j.gene.2013.08.00323954230Search in Google Scholar

Cho YH, Lee SY, Jeong DW, Cho AR, Jeon JS, Kim YJ, et al. Metabolic syndrome is associated with lower plasma levels of desacyl ghrelin and total ghrelin in asymptomatic middle-aged Korean men. J Obes Metab Synd. 2017; 26(2): 114-121.Cho YH Lee SY Jeong DW Cho AR Jeon JS Kim YJ et al Metabolic syndrome is associated with lower plasma levels of desacyl ghrelin and total ghrelin in asymptomatic middle-aged Korean men J Obes Metab Synd 2017 26 2 114 12110.7570/jomes.2017.26.2.114648490331089505Search in Google Scholar

You Y, Yu Y, Wu Y, Rao W, Zhang Y, Liu Y, et al. Association study between ghrelin gene polymorphism and metabolic syndrome in a Han Chinese population. Clin Lab. 2017; 63(1): 175-181.You Y Yu Y Wu Y Rao W Zhang Y Liu Y et al Association study between ghrelin gene polymorphism and metabolic syndrome in a Han Chinese population Clin Lab 2017 63 1 175 18110.7754/Clin.Lab.2016.16071528164505Search in Google Scholar

Berthold HK, Giannakidou E, Krone W, Trégouët DA, Gouni-Berthold I. Influence of ghrelin gene polymorphisms on hypertension and atherosclerotic disease. Hypertens Res. 2010; 33(2): 155-160.Berthold HK Giannakidou E Krone W Trégouët DA Gouni-Berthold I Influence of ghrelin gene polymorphisms on hypertension and atherosclerotic disease Hypertens Res 2010 33 2 155 16010.1038/hr.2009.19420010782Search in Google Scholar

dos Santos IC, Frigeri HR, Daga DR, Rea RR, Almeida AC, de Souza EM, et al. The ghrelin gene allele 51Q (rs34911341) is a protective factor against the development of gestational diabetes. Clin Chim Acta. 2010; 411(11-12): 886-887.dos Santos IC Frigeri HR Daga DR Rea RR Almeida AC de Souza EM et al The ghrelin gene allele 51Q (rs34911341) is a protective factor against the development of gestational diabetes Clin Chim Acta 2010 411 11-12 886 88710.1016/j.cca.2010.02.01020152820Search in Google Scholar

Ukkola O, Ravussin E, Jacobson P, Pérusse L, Rankinen T, Tschöp M, et al. Role of ghrelin polymorphisms in obesity based on three different studies. Obes Res. 2002; 10(8): 782-791.Ukkola O Ravussin E Jacobson P Pérusse L, Rankinen T Tschöp M et al Role of ghrelin polymorphisms in obesity based on three different studies Obes Res 2002 10 8 782 79110.1038/oby.2002.10612181387Search in Google Scholar

Suchankova P, Yan J, Schwandt ML, Stangl BL, Jerlhag E, Engel JA, et al. The Leu72Met polymorphism of the prepro-ghrelin gene is associated with alcohol consumption and subjective responses to alcohol: Preliminary findings. Alcohol Alcohol. 2017; 52(4): 425-430.Suchankova P Yan J Schwandt ML Stangl BL Jerlhag E Engel JA et al The Leu72Met polymorphism of the prepro-ghrelin gene is associated with alcohol consumption and subjective responses to alcohol: Preliminary findings Alcohol Alcohol 2017 52 4 425 43010.1093/alcalc/agx021586051928481975Search in Google Scholar

Ando T, Komaki G, Naruo T, Okabe K, Takii M, Kawai K, et al. Possible role of preproghrelin gene poly-morphisms in susceptibility to bulimia nervosa. Am J Med Genet B Neuropsychiatr Genet. 2006; 141B(8): 929-934.Ando T Komaki G Naruo T Okabe K Takii M Kawai K et al Possible role of preproghrelin gene poly-morphisms in susceptibility to bulimia nervosa Am J Med Genet B Neuropsychiatr Genet 2006 141B 8 92993410.1002/ajmg.b.3038716921495Search in Google Scholar

Steinle NI, Pollin TI, O’Connell JR, Mitchell BD, Shuldinr AR. J Clin Endocrinol Metab. 2005; 90(12): 6672-6677.Steinle NI Pollin TI O’Connell JR Mitchell BD Shuldinr AR J Clin Endocrinol Metab 2005 90 12 6672 667710.1210/jc.2005-054916204371Search in Google Scholar

Huang R, Tian S, Cai R, Sun J, Shen Y, Wang S. Ethnicity-specific association between ghrelin Leu72Met polymorphism and type 2 diabetes mellitus susceptibility: An updated meta-analysis. Front Genet. 2018; 9: 541.Huang R Tian S Cai R Sun J Shen Y Wang S Ethnicity-specific association between ghrelin Leu72Met polymorphism and type 2 diabetes mellitus susceptibility: An updated meta-analysis Front Genet 2018 9 54110.3389/fgene.2018.00541624665330487812Search in Google Scholar

Su M, Qiu L, Wang Q, Jiang Z, Liu XJ, Lin J, et al. Associations of Leu72Met polymorphism of preproghrelin with ratios of plasma lipids are diversified by a high-carbohydrate diet in healthy Chinese adolescents. Ann Nutr Metab. 2015; 67(4): 236-242.Su M Qiu L Wang Q Jiang Z Liu XJ Lin J et al Associations of Leu72Met polymorphism of preproghrelin with ratios of plasma lipids are diversified by a high-carbohydrate diet in healthy Chinese adolescents Ann Nutr Metab 2015 67 4 236 24210.1159/00044077726536003Search in Google Scholar

eISSN:
1311-0160
Langue:
Anglais
Périodicité:
2 fois par an
Sujets de la revue:
Medicine, Basic Medical Science, other