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Figure 1

Images a-d show immunohistochemical staining of GIST samples with spindle-shaped tumor cells, negative for EGFR expression. Images e-f indicate hematoxylin and eosin staining of GIST samples with spindle-shaped tumor cells. Image g represents the positive control, expressing EGFR. All images were taken in 40× magnification. Image h represents the control EGFR sample from a chorionic villus sample.
Images a-d show immunohistochemical staining of GIST samples with spindle-shaped tumor cells, negative for EGFR expression. Images e-f indicate hematoxylin and eosin staining of GIST samples with spindle-shaped tumor cells. Image g represents the positive control, expressing EGFR. All images were taken in 40× magnification. Image h represents the control EGFR sample from a chorionic villus sample.

Patient details such as age, gender, tumor locations, cell types and EGFR gene mutation status are shown.

Sex Mean Age Tumor Location (%) Tumor Cell Type (%) Status of Analyzed EGFR Gene Mutations Exons (codons) EGFR Expression
18 (719) 19 (deletion) 20 (768; 790) 21 (858; 861)
F 57.2±5.6 duodenum (21.5) spindle cell (100.0) wild type wild type wild type wild type negative
ileum (10.5) epithelioid (100.0) wild type wild type wild type wild type negative
small intestine (26.3); epithelioid (20.0);mixed (60.0);spindle cell (20.0) wild type wild type wild type wild type negative
stomach (38.8) spindle cell (57.0);mixed (14.2);epithelioid (28.8) wild type wild type wild type wild type negative
transverse colon (5.2) mixed (100.0) wild type wild type wild type wild type negative
M 62.6±10.5 colon (9.5) spindle cell (100.0) wild type wild type wild type wild type negative
descending colon (4.7) mixed (100.0) wild type wild type wild type wild type negative
duodenum (4.7) spindle cell (100.0) wild type wild type wild type wild type negative
ileum (4.7) mixed (100.0) wild type wild type wild type wild type negative
jejenum (4.7) spindle cell (100.0) wild type wild type wild type wild type negative
small intestine (19.0) spindle cell (25.0);mixed (75.0) wild type wild type wild type wild type negative
Stomach (52.4) spindle cell (54.5);mixed (36.3);epithelioid (9.2) wild type wild type wild type wild type negative
eISSN:
1311-0160
Langue:
Anglais
Périodicité:
2 fois par an
Sujets de la revue:
Medicine, Basic Medical Science, other