Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide
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27 mai 2014
![Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide's Cover Image](https://sciendo-parsed.s3.eu-central-1.amazonaws.com/6470799b71e4585e08a9e01d/cover-image.jpg)
À propos de cet article
Publié en ligne: 27 mai 2014
Pages: 34 - 37
DOI: https://doi.org/10.2478/acs-2014-0007
Mots clés
© Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava
This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
The title compound, C11H16NOS・I, is chiral molecule with three stereogenic centres. The absolute configuration was assigned from the synthesis and confirmed by the structure determination. The central six-membered ring of the indolizine moiety adopts a half-chair conformation with atom displaced by 0.655 (2) A from the plane of the oder remaining five atoms. The pyrrolidine ring adopts an envelope conformation, with the greatest deviation from the mean plane of the ring being 0.646 (2) A for the bridgehead N atom. The crystal structure of the title compound is stabilized by O-H・・・I and C-H・・・O hydrogen bonds.