<abstract xmlns="http://www.w3.org/1999/xhtml"> The title compound, C11H16NOS・I, is chiral molecule with three stereogenic centres. The absolute configuration was assigned from the synthesis and confirmed by the structure determination. The central six-membered ring of the indolizine moiety adopts a half-chair conformation with atom displaced by 0.655 (2) A from the plane of the oder remaining five atoms. The pyrrolidine ring adopts an envelope conformation, with the greatest deviation from the mean plane of the ring being 0.646 (2) A for the bridgehead N atom. The crystal structure of the title compound is stabilized by O-H・・・I and C-H・・・O hydrogen bonds.</abstract>

The title compound, C11H16NOS・I, is chiral molecule with three stereogenic centres. The absolute configuration was assigned from the synthesis and confirmed by the structure determination. The central six-membered ring of the indolizine moiety adopts a half-chair conformation with atom displaced by 0.655 (2) A from the plane of the oder remaining five atoms. The pyrrolidine ring adopts an envelope conformation, with the greatest deviation from the mean plane of the ring being 0.646 (2) A for the bridgehead N atom. The crystal structure of the title compound is stabilized by O-H・・・I and C-H・・・O hydrogen bonds.

Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide

Institute of Analytical Chemistry, Faculty of Chemical and Food Technology, Slovak Technical University, Radlinského 9, SK-812 37 Bratislava, Slovak Republic

Institute of Mathematics and Physics, Faculty of Mechanical Engineering, Slovak University of Technologyy, Námestie slobody 17, SK-812 31 Bratislava, Slovak Republic

Institute of Organic Chemistry, Catalysis and Petrochemistry, Faculty of Chemical and Food Technology,Slovak Technical University, Radlinského 9, SK-812 37 Bratislava, Slovak Republic

Acta Chimica Slovaca

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

The title compound, C11H16NOS・I, is chiral molecule with three stereogenic centres. The absolute configuration was assigned from the synthesis and confirmed by...

Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide

Publié en ligne: 27 mai 2014

Pages: 34 - 37

DOI: https://doi.org/10.2478/acs-2014-0007

Mots clés
conformation, crystal structure, hydrogen bonds, indolizine, single-crystal X-ray study

© Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Crystal and molecular structure of (5S,8aS,9S)-9-hydroxy- 5-methyl- 4,6,7,8,8a,9-hexahydrothieno-[ 3,2-f] indolizin-5-ium iodide

Publié en ligne: 27 mai 2014

Pages: 34 - 37

DOI: https://doi.org/10.2478/acs-2014-0007

Mots clésconformation, crystal structure, hydrogen bonds, indolizine, single-crystal X-ray study

© Faculty of Chemical and Food Technology, Slovak University of Technology in Bratislava

This article is distributed under the terms of the Creative Commons Attribution Non-Commercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Mots clés
conformation, crystal structure, hydrogen bonds, indolizine, single-crystal X-ray study