<abstract xmlns="http://www.w3.org/1999/xhtml"><p><italic>Prunella vulgaris</italic> L. grows in spontaneous flora of Romania in wet places, fields, meadows, unpopulated areas, both in the sun and in the shade. The plant is rich in phenolic acids (caffeic acid, rosmarinic acid), pentacyclic triterpenic compounds (ursolic, oleanolic, betulinic acid) and flavonoids (rutoside, quercetin). <italic>Prunella vulgaris</italic> L. has shown numerous pharmacological actions: antioxidant, anti-allergic, antimicrobial, immunostimulatory activities. The aim of the study was to evaluate the phytochemical and pharmacological profile of the leaves and spike inflorescence of <italic>Prunella vulgaris</italic> L. collected from Romania. The polyphenol content in leaves was found to be 63.78 ± 2.01 mg GAE/g dry weight in the methanolic extract and 45.73 ± 13.87 mg GAE/g in the aqueous extract. In the spike inflorescence, total polyphenol content was 36.44 ± 6.73 mg GAE/g in the methanolic extract and 26.49 ± 2.97 mg GAE/g in the aqueous extract. The results from the antioxidant assays (DPPH and ABTS) were not significantly different between the two herbal drugs. Further studies are needed in order to quantify the active compounds.</p></abstract>

Prunella vulgaris L. grows in spontaneous flora of Romania in wet places, fields, meadows, unpopulated areas, both in the sun and in the shade. The plant is rich in phenolic acids (caffeic acid, rosmarinic acid), pentacyclic triterpenic compounds (ursolic, oleanolic, betulinic acid) and flavonoids (rutoside, quercetin). Prunella vulgaris L. has shown numerous pharmacological actions: antioxidant, anti-allergic, antimicrobial, immunostimulatory activities. The aim of the study was to evaluate the phytochemical and pharmacological profile of the leaves and spike inflorescence of Prunella vulgaris L. collected from Romania. The polyphenol content in leaves was found to be 63.78 ± 2.01 mg GAE/g dry weight in the methanolic extract and 45.73 ± 13.87 mg GAE/g in the aqueous extract. In the spike inflorescence, total polyphenol content was 36.44 ± 6.73 mg GAE/g in the methanolic extract and 26.49 ± 2.97 mg GAE/g in the aqueous extract. The results from the antioxidant assays (DPPH and ABTS) were not significantly different between the two herbal drugs. Further studies are needed in order to quantify the active compounds.

Phytochemical Characterization of Transilvanian <italic>Prunella vulgaris</italic>

Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy

George Emil Palade University of Medicine, Pharmacy, Science and Technology of Târgu Mureş

Discipline of Pharmacognosy and Phytotherapy, Faculty of Pharmacy

Department of Analytical Chemistry and Drug Analysis, Faculty of Pharmacy

Acta Biologica Marisiensis

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Phytochemical Characterization of Transilvanian 

Prunella vulgaris L. grows in spontaneous flora of Romania in wet places, fields, meadows, unpopulated areas, both in the sun and in the shade. The plant is...

Phytochemical Characterization of Transilvanian Prunella vulgaris

Publié en ligne: 29 juin 2020

Pages: 62 - 69

Reçu: 22 avr. 2020

Accepté: 09 juin 2020

DOI: https://doi.org/10.2478/abmj-2020-0005

Mots clés
total polyphenols, antioxidant, Lamiaceae

© 2020 Alexandra Groşan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Phytochemical Characterization of Transilvanian Prunella vulgaris

Publié en ligne: 29 juin 2020

Pages: 62 - 69

Reçu: 22 avr. 2020

Accepté: 09 juin 2020

DOI: https://doi.org/10.2478/abmj-2020-0005

Mots cléstotal polyphenols, antioxidant, Lamiaceae

© 2020 Alexandra Groşan et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License.

Mots clés
total polyphenols, antioxidant, Lamiaceae