[1. *** Europea Pharmacopeiaea, 8th edition, 2011, pp. 1219-1220.]Search in Google Scholar
[2. Aybastier Ö, Şahin S, Işik E, Demir C. (2011) Determination of total phenolic content in Prunella L. by horseradish peroxidase immobilized onto chitosan beads. Anal. Methods 3(10):2289–2297. doi: 10.1039/c1ay05218g10.1039/c1ay05218g]Search in Google Scholar
[3. Ayeleso TB, Matumba MG, Mukwevho E (2017) Oleanolic acid and its derivatives: Biological activities and therapeutic potential in chronic diseases. Molecules 22(11):1915. doi: 10.3390/molecules2211191510.3390/molecules22111915615024929137205]Search in Google Scholar
[4. Cao H, Cheng WX, Li C, Pan XL, Xie XG, Li TH (2005) DFT study on the antioxidant activity of rosmarinic acid. J. Mol. Struct. THEOCHEM 719:177–183. doi: 10.1016/j.theochem.2005.01.02910.1016/j.theochem.2005.01.029]Search in Google Scholar
[5. Chen Y, Zhang X, Guo Q, Cao L, Qin Q, Li C, Zhao M, Wang M (2019) Plant morphology, physiological characteristics, accumulation of secondary metabolites and antioxidant activities of Prunella vulgaris L. under UV solar exclusion. Biol. Res. 52(1):17. doi: 10.1186/s40659-019-0225-810.1186/s40659-019-0225-8644240930935421]Search in Google Scholar
[6. Chew KK, Khoo MZ, Ng SY, Thoo, YY, Aida WW, Ho CW (2011) Effect of ethanol concentration, extraction time and extraction temperature on the recovery of phenolic compounds and antioxidant capacity of Orthosiphon stamineus extracts. International Food Research Journal 18(4):1427.]Search in Google Scholar
[7. Collins NH, Lessey EC, DuSell CD, McDonnell DP, Fowler L, Palomino WA, Lessey BA (2009) Characterization of antiestrogenic activity of the Chinese herb, Prunella vulgaris, using in vitro and in vivo (Mouse Xenograft) models. Biology of reproduction 80(2):375-383.10.1095/biolreprod.107.065375274640518923163]Search in Google Scholar
[8. Ding H, Hu X, Xu X, Zhang G, Gong D (2018) Inhibitory mechanism of two allosteric inhibitors, oleanolic acid and ursolic acid on α-glucosidase. Int. J. Biol. Macromol. 107:1844–1855. doi: 10.1016/j.ijbiomac.2017.10.04010.1016/j.ijbiomac.2017.10.04029030193]Search in Google Scholar
[9. Du H, Chen XQ (2009) A comparative study of the separation of oleanolic acid and ursolic acid in Prunella vulgaris by high-performance liquid chromatography and cyclodextrin-modified micellar electrokinetic chromatography. J. Iran. Chem. Soc. 6(2):334–340. doi: 10.1007/BF0324584210.1007/BF03245842]Search in Google Scholar
[10. Fazal H, Abbasi BH, Ahmad N, Ali SS, Akbar F, Kanwal F (2016) Correlation of different spectral lights with biomass accumulation and production of antioxidant secondary metabolites in callus cultures of medicinally important Prunella vulgaris L. Journal of Photochemistry and Photobiology B: Biology 159:1-7.10.1016/j.jphotobiol.2016.03.00826995670]Search in Google Scholar
[11. Feng L, Jia X, Zhu MM, Chen Y, Shi F (2010) Antioxidant activities of total phenols of Prunella vulgaris L. in vitro and in tumor-bearing mice. Molecules 15(12):9145–9156. doi: 10.3390/molecules1512914510.3390/molecules15129145625916721150830]Search in Google Scholar
[12. Fu JY, Qian LB, Zhu LG, Te Liang H, Tan YN, Lu HT, Lu JF, Wang HP, Xia Q (2011) Betulinic acid ameliorates endothelium-dependent relaxation in l-NAME-induced hypertensive rats by reducing oxidative stress. Eur. J. Pharm. Sci. 44(3):385–391. doi: 10.1016/j.ejps.2011.08.02510.1016/j.ejps.2011.08.02521907795]Search in Google Scholar
[13. Gupta D (2010) Reactive oxygen species and antioxidants in higher plants. Boca Raton: CRC Press, pp. 333-334.10.1201/9781439854082]Search in Google Scholar
[14. Han EH, Choi JH, Hwang YP, Park HJ, Choi CY, Chung YC, Seo JK, Jeong HG (2009) Immunostimulatory activity of aqueous extract isolated from Prunella vulgaris. Food Chem. Toxicol. 47(1):62–69. doi: 10.1016/j.fct.2008.10.01010.1016/j.fct.2008.10.01018983886]Search in Google Scholar
[15. Hwang YJ, Lee EJ, Kim HR, Hwang KA (2013a) In vitro antioxidant and anticancer effects of solvent fractions from Prunella vulgaris var. lilacina. BMC Complement. Altern. Med. 13(1):310. doi: 10.1186/1472-6882-13-31010.1186/1472-6882-13-310422620124206840]Search in Google Scholar
[16. Hwang YJ, Lee EJ, Kim HR, Hwang KA (2013b) NF-κB-targeted anti-inflammatory activity of Prunella vulgaris var. lilacina in macrophages RAW 264.7. Int. J. Mol. Sci. 14(11):21489–21503. doi: 10.3390/ijms14112148910.3390/ijms141121489385601724177568]Search in Google Scholar
[17. Kashyap D, Tuli HS, Sharma AK (2016) Ursolic acid (UA): A metabolite with promising therapeutic potential. Life Sci. 146:201–213. doi: 10.1016/j.lfs.2016.01.01710.1016/j.lfs.2016.01.01726775565]Search in Google Scholar
[18. Komal S, Kazmi SAJ, Khan JA, Gilani MM (2018) Antimicrobial activity of Prunella vulgaris extracts against multi-drug resistant Escherichia coli from patients of urinary tract infection. Pakistan J. Med. Sci. 34(3):616–620. doi: 10.12669/pjms.343.1498210.12669/pjms.343.14982604153030034426]Search in Google Scholar
[19. Lee KJ, Oh YC, Cho WK, Ma JY (2015) Antioxidant and anti-inflammatory activity determination of one hundred kinds of pure chemical compounds using offline and online screening HPLC assay. Evidence-Based Complementary and Alternative Medicine, 2015.10.1155/2015/165457460940126504472]Search in Google Scholar
[20. Li BY, Hu Y, Li J, Shi K, Shen YF, Zhu B, Wang GX (2019) Ursolic acid from Prunella vulgaris L. efficiently inhibits IHNV infection in vitro and in vivo. Virus Res. 273:197741. doi: 10.1016/j.virusres.2019.197741.10.1016/j.virusres.2019.19774131494148]Search in Google Scholar
[21. Liu ZX, Hua YJ, Wang SN, Zou LS, Liu XH, Zhao H, Yan Y (2017) Quality Evaluation of Prunellae Spica Based on Simultaneous Determination of Multiple Bioactive Constituents Combined with Grey Relational Analysis. Natural Product Communications, 12(7). 1934578X1701200729.10.1177/1934578X1701200729]Search in Google Scholar
[22. Mahboubi M, Mahboubi A, Kazempour N (2015) The antimicrobial activity of Prunella vulgaris extracts. Herba Pol. 61(1):31–38. doi: 10.1515/hepo-2015-000810.1515/hepo-2015-0008]Search in Google Scholar
[23. Morteza-Semnani K, Saeedi M, Akbarzadeh M (2006) The essential oil composition of Prunella vulgaris L. J. Essent. Oil-Bearing Plants 9(3):257–260. doi: 10.1080/0972060X.2006.1064350010.1080/0972060X.2006.10643500]Search in Google Scholar
[24. Nayak A, Khan MA, Sharma P, Mishra RM (2018) Phytochemical screening, antioxidant and antimicrobial activities of Prunella vulgaris for oral thrush. Journal of Drug Delivery and Therapeutics 8(5):251-258.10.22270/jddt.v8i5-s.1966]Search in Google Scholar
[25. Pinkas M, Trotin F, Peng W, Torck M (1994) Use, chemistry and pharmacology of ten chinese medicinal plants. Fitoterapia 65(4):343–353.]Search in Google Scholar
[26. Ryu SY, Oak MH, Yoon SK, Cho DI, Yoo GS, Kim TS, Kim KM (2000) Anti-allergic and anti-inflammatory triterpenes from the herb of Prunella vulgaris. Planta Med. 66(4):358–360. doi: 10.1055/s-2000-853110.1055/s-2000-8531]Search in Google Scholar
[27. Sârbu I, Ştefan N, Oprea A (2013) Plante Vasculare din România - Determinator ilustrat de teren, Editura Victor B Victor, Bucureşti 18-22: 650]Search in Google Scholar
[28. Sárosi S, Bernáth J, Bertoli A, Pistelli L, Burchi G, Antonetti M, Benvenuti S (2015) Effect of different plant origins and climatic conditions on the total phenolic content and total antioxidant capacity of self-heal (Prunella vulgaris L.). Acta Hortic. 925:49–56. doi: 10.17660/actahortic.2011.925.510.17660/ActaHortic.2011.925.5]Search in Google Scholar
[29. Shan B, Cai YZ, Sun M, Corke H (2005) Antioxidant capacity of 26 spice extracts and characterization of their phenolic constituents. J. Agric. Food Chem., 53(20):7749–7759. doi: 10.1021/jf051513y10.1021/jf051513y]Search in Google Scholar
[30. Shanaida M, Golembiovska O, Hudz N, Wieczorek PP (2018) Phenolic compounds of herbal infusions obtained from some species of the Lamiaceae family. Curr. Issues Pharm. Med. Sci. 31(4):194–199. doi: 10.1515/cipms-2018-003610.1515/cipms-2018-0036]Search in Google Scholar
[31. Shekarchi M, Hajimehdipoor H, Saeidnia S, Gohari AR, Hamedani MP (2012) Comparative study of rosmarinic acid content in some plants of Labiatae family. Pharmacognosy magazine, 8(29):37.10.4103/0973-1296.93316]Search in Google Scholar
[32. Shen Q, Zhang B, Xu R, Wang Y, Ding X, Li P (2010) Antioxidant activity in vitro of selenium-contained protein from the se-enriched. Bifodobacterium animalis 01. Anaerobe, 16:380–386.10.1016/j.anaerobe.2010.06.006]Search in Google Scholar
[33. Singh MK, Joshi C, Joshi N, Sharma R, Brijwal L, Kumar RS (2015) Scrutinizing the antioxidant potential of Prunella vulgaris L. : A medicinal plant from central Himalayan region. Int. J. Fundam. Appl. Sci. 4(1):1–8.]Search in Google Scholar
[34. Singleton VL, Orthofer R, Lamuela-Raventos RM (1999) Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol. 299(1974):152–178. doi: 10.1016/S0076-6879(99)99017-110.1016/S0076-6879(99)99017-1]Search in Google Scholar
[35. Sochor J, Ryvolova M, Krystofova O, Salas P, Hubalek J, Adam V, Provaznik I (2010) Fully automated spectrometric protocols for determination of antioxidant activity: Advantages and disadvantages. Molecules, 15(12):8618–8640.10.3390/molecules15128618625919521116230]Search in Google Scholar
[36. Vostálová J, Zdařilová A, Svobodová A (2010) Prunella vulgaris extract and rosmarinic acid prevent UVB-induced DNA damage and oxidative stress in HaCaT keratinocytes. Archives of dermatological research, 302(3):171–181.10.1007/s00403-009-0999-619862537]Search in Google Scholar
[37. Wagner H, Bauer R, Melchart, D, Staudinger A (2016) Spica Prunellae–Xiakucao. In Chromatographic Fingerprint Analysis of Herbal Medicines, 4:225–237.10.1007/978-3-319-32328-2_22]Search in Google Scholar
[38. Zdařilová A, Svobodová A, Šimánek V, Ulrichová J (2009) Prunella vulgaris extract and rosmarinic acid suppress lipopolysaccharide-induced alteration in human gingival fibroblasts. Toxicology in Vitro, 23(3):386–392.10.1016/j.tiv.2008.12.02119159670]Search in Google Scholar
[39. Zheleva-Dimitrova D, Nedialkov P, Kitanov G (2010) Radical scavenging and antioxidant activities of methanolic extracts from Hypericum species growing in Bulgaria. Pharmacognosy magazine, 6(22):74.10.4103/0973-1296.62889]Search in Google Scholar
[40. Zheng J, He J, Ji B, Li Y, Zhang X (2007) Antihyperglycemic activity of Prunella vulgaris L. in streptozotocin-induced diabetic mice. Asia Pac. J. Clin. Nutr., 16(1):427–431. doi: 10.6133/apjcn.2007.16.s1.78]Search in Google Scholar