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Alginate–gelatin hydrogel supplemented with platelet concentrates can be used as bioinks for scaffold printing

Tuyet Thi Vi Le

Tuyet Thi Vi Le

  • Department of Physiology and Animal Biotechnology, Biology and Biotechnology Faculty, University of ScienceHo Chi Minh City, Vietnam
  • Laboratory of Tissue Engineering and Biomedical Materials, University of ScienceHo Chi Minh City, Vietnam
  • Vietnam National UniversityHo Chi Minh City, Vietnam
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Le, Tuyet Thi Vi
, 
Nghia Thi Hieu Phan

Nghia Thi Hieu Phan

  • Department of Physiology and Animal Biotechnology, Biology and Biotechnology Faculty, University of ScienceHo Chi Minh City, Vietnam
  • Laboratory of Tissue Engineering and Biomedical Materials, University of ScienceHo Chi Minh City, Vietnam
  • Vietnam National UniversityHo Chi Minh City, Vietnam
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Phan, Nghia Thi Hieu
 et 
Ha Le Bao Tran

Ha Le Bao Tran

  • Department of Physiology and Animal Biotechnology, Biology and Biotechnology Faculty, University of ScienceHo Chi Minh City, Vietnam
  • Laboratory of Tissue Engineering and Biomedical Materials, University of ScienceHo Chi Minh City, Vietnam
  • Vietnam National UniversityHo Chi Minh City, Vietnam
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Tran, Ha Le Bao
  
26 oct. 2023
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Catégorie d'article: Original article
Publié en ligne: 26 oct. 2023
Pages: 222 - 229
DOI: https://doi.org/10.2478/abm-2023-0063
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© 2023 Tuyet Thi Vi Le et al., published by Sciendo
This work is licensed under the Creative Commons Attribution 4.0 International License.

Figure 1.

The sol–gel transition of bioinks over time through inversion test. (A) AG bioink; (B) AGP bioink; (C) AGF bioink. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP.
The sol–gel transition of bioinks over time through inversion test. (A) AG bioink; (B) AGP bioink; (C) AGF bioink. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP.

Figure 2.

The pH of bioinks. (A) AG bioink; (B) AGP bioink; (C) AGF bioink. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP.
The pH of bioinks. (A) AG bioink; (B) AGP bioink; (C) AGF bioink. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP.

Figure 3.

GFs release from scaffolds over time. (A) AGP and AGF scaffolds, (B) Growth factors release. AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP; GFs, growth factors; PDGF-AB; platelet-derived GF-AB; VEGF, vascular endothelial GF.
GFs release from scaffolds over time. (A) AGP and AGF scaffolds, (B) Growth factors release. AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP; GFs, growth factors; PDGF-AB; platelet-derived GF-AB; VEGF, vascular endothelial GF.

Figure 4.

The RGR of cells in the serum-free extracts. ****P < 0.0001. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP; RGR, relative growth rate.
The RGR of cells in the serum-free extracts. ****P < 0.0001. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP; RGR, relative growth rate.

Figure 5.

The RGR of cells in the serum-containing extracts. ***P < 0.001, ****P < 0.0001. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP; RGR, relative growth rate.
The RGR of cells in the serum-containing extracts. ***P < 0.001, ****P < 0.0001. AG, alginate–gelatin; AGF, alginate–gelatin-PRF; AGP, alginate–gelatin-PRP; RGR, relative growth rate.
Langue:
Anglais
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6 fois par an
Sujets de la revue:
Médecine, Professions d'assistance, soins infirmiers, Sciences médicales de base, Sciences médicales de base, autres, Médecine clinique, Médecine clinique, autres
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