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Tao H, Li Z, Mei Y, Li X, Lou H, Dong L, Zhou L. Integrative bioinformatics analysis of a prognostic index and immunotherapeutic targets in renal cell carcinoma. Int Immunopharmacol. 2020; 87:106832. doi: 10.1016/j.intimp.2020.106832TaoHLiZMeiYLiXLouHDongLZhouLIntegrative bioinformatics analysis of a prognostic index and immunotherapeutic targets in renal cell carcinomaInt Immunopharmacol20208710683210.1016/j.intimp.2020.106832Open DOISearch in Google Scholar
Monteiro MS, Barros AS, Pinto J, Carvalho M, Pires-Luís AS, Henrique R, et al. Nuclear magnetic resonance metabolomics reveals an excretory metabolic signature of renal cell carcinoma. Sci Rep. 2016; 6:37275. doi: 10.1038/srep37275MonteiroMSBarrosASPintoJCarvalhoMPires-LuísASHenriqueRNuclear magnetic resonance metabolomics reveals an excretory metabolic signature of renal cell carcinomaSci Rep201663727510.1038/srep37275Open DOISearch in Google Scholar
Meng H, Jiang X, Cui J, Yin G, Shi B, Liu Q, et al. Genomic analysis reveals novel specific metastatic mutations in Chinese clear cell renal cell carcinoma. Biomed Res Int. 2020; 2020:2495157. doi: 10.1155/2020/2495157MengHJiangXCuiJYinGShiBLiuQGenomic analysis reveals novel specific metastatic mutations in Chinese clear cell renal cell carcinomaBiomed Res Int20202020249515710.1155/2020/2495157Open DOISearch in Google Scholar
Huang C, Li J, Zhang X, Xiong T, Ye J, Yu J, Gui Y. The miR-140-5p/KLF9/KCNQ1 axis promotes the progression of renal cell carcinoma. FASEB J. 2020; 34:10623–39.HuangCLiJZhangXXiongTYeJYuJGuiYThe miR-140-5p/KLF9/KCNQ1 axis promotes the progression of renal cell carcinomaFASEB J2020341062339Search in Google Scholar
Znaor A, Lortet-Tieulent J, Laversanne M, Jemal A, Bray F. International variations and trends in renal cell carcinoma incidence and mortality. Eur Urol. 2015; 67:519–30.ZnaorALortet-TieulentJLaversanneMJemalABrayFInternational variations and trends in renal cell carcinoma incidence and mortalityEur Urol20156751930Search in Google Scholar
Chen Y, Du J, Wang Y, Shi H, Jiang Q, Wang Y, et al. MicroRNA-497-5p induces cell cycle arrest of cervical cancer cells in S phase by targeting CBX4. Onco Targets Ther. 2019; 12:10535–45.ChenYDuJWangYShiHJiangQWangYMicroRNA-497-5p induces cell cycle arrest of cervical cancer cells in S phase by targeting CBX4Onco Targets Ther2019121053545Search in Google Scholar
Mathew LK, Lee SS, Skuli N, Rao S, Keith B, Nathanson KL, et al. Restricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal carcinomas enhances HIF2α activity. Cancer Discov. 2014; 4:53–60.MathewLKLeeSSSkuliNRaoSKeithBNathansonKLRestricted expression of miR-30c-2-3p and miR-30a-3p in clear cell renal carcinomas enhances HIF2α activityCancer Discov201445360Search in Google Scholar
Tang CT, Liang Q, Yang L, Lin XL, Wu S, Chen Y, et al. RAB31 targeted by MiR-30c-2-3p regulates the GLI1 signaling pathway, affecting gastric cancer cell proliferation and apoptosis. Front Oncol. 2018; 8:554. doi: 10.3389/fonc.2018.00554TangCTLiangQYangLLinXLWuSChenYRAB31 targeted by MiR-30c-2-3p regulates the GLI1 signaling pathway, affecting gastric cancer cell proliferation and apoptosisFront Oncol2018855410.3389/fonc.2018.00554Open DOISearch in Google Scholar
Shukla K, Sharma AK, Ward A, Will R, Hielscher T, Balwierz A, et al. MicroRNA-30c-2-3p negatively regulates NF-kB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Mol Oncol. 2015; 9:1106–19.ShuklaKSharmaAKWardAWillRHielscherTBalwierzAMicroRNA-30c-2-3p negatively regulates NF-kB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancerMol Oncol20159110619Search in Google Scholar
Dougherty AC, Hawaz MG, Hoang KG, Trac J, Keck JM, Ayes C, Deweese JE. Exploration of the role of the C-terminal domain of human DNA topoisomerase IIα in catalytic activity. ACS Omega. 2021; 6:25892–903.DoughertyACHawazMGHoangKGTracJKeckJMAyesCDeweeseJEExploration of the role of the C-terminal domain of human DNA topoisomerase IIα in catalytic activityACS Omega2021625892903Search in Google Scholar
Zhang M, Liang C, Chen Q, Yan H, Xu J, Zhao H, et al. Histone H2A phosphorylation recruits topoisomerase IIa to centromeres to safeguard genomic stability. EMBO J. 2020; 39:e101863. doi: 10.15252/embj.2019101863ZhangMLiangCChenQYanHXuJZhaoHHistone H2A phosphorylation recruits topoisomerase IIa to centromeres to safeguard genomic stabilityEMBO J202039e10186310.15252/embj.2019101863Open DOISearch in Google Scholar
Antoniou-Kourounioti M, Mimmack ML, Porter ACG, Farr CJ. The impact of the C-terminal region on the interaction of topoisomerase II alpha with mitotic chromatin. Int J Mol Sci. 2019; 20:1238. doi: 10.3390/ijms20051238Antoniou-KourouniotiMMimmackMLPorterACGFarrCJThe impact of the C-terminal region on the interaction of topoisomerase II alpha with mitotic chromatinInt J Mol Sci201920123810.3390/ijms20051238Open DOISearch in Google Scholar
Pei YF, Yin XM, Liu XQ. TOP2A induces malignant character of pancreatic cancer through activating β-catenin signaling pathway. Biochim Biophys Acta Mol Basis Dis. 2018; 1864:197–207.PeiYFYinXMLiuXQTOP2A induces malignant character of pancreatic cancer through activating β-catenin signaling pathwayBiochim Biophys Acta Mol Basis Dis20181864197207Search in Google Scholar
Liu T, Zhang H, Yi S, Gu L, Zhou M. Mutual regulation of MDM4 and TOP2A in cancer cell proliferation. Mol Oncol. 2019; 13:1047–58.LiuTZhangHYiSGuLZhouMMutual regulation of MDM4 and TOP2A in cancer cell proliferationMol Oncol201913104758Search in Google Scholar
Wang B, Shen Y, Zou Y, Qi Z, Huang G, Xia S, et al. TOP2A promotes cell migration, invasion and epithelial–mesenchymal transition in cervical cancer via activating the PI3K/AKT signaling. Cancer Manag Res. 2020; 12:3807–14.WangBShenYZouYQiZHuangGXiaSTOP2A promotes cell migration, invasion and epithelial–mesenchymal transition in cervical cancer via activating the PI3K/AKT signalingCancer Manag Res202012380714Search in Google Scholar
Lyu WJ, Shu YJ, Liu YB, Dong P. Topoisomerase II alpha promotes gallbladder cancer proliferation and metastasis through activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathway. Chin Med J (Engl). 2020; 133:2321–9.LyuWJShuYJLiuYBDongPTopoisomerase II alpha promotes gallbladder cancer proliferation and metastasis through activating phosphatidylinositol 3-kinase/protein kinase B/mammalian target of rapamycin signaling pathwayChin Med J (Engl)202013323219Search in Google Scholar
Yuan L, Zeng G, Chen L, Wang G, Wang X, Cao X, et al. Identification of key genes and pathways in human clear cell renal cell carcinoma (ccRCC) by co-expression analysis. Int J Biol Sci. 2018; 14:266–79.YuanLZengGChenLWangGWangXCaoXIdentification of key genes and pathways in human clear cell renal cell carcinoma (ccRCC) by co-expression analysisInt J Biol Sci20181426679Search in Google Scholar
Rezghi Barez S, Movahedian Attar A, Aghaei M. MicroRNA-30c-2-3p regulates ER stress and induces apoptosis in ovarian cancer cells underlying ER stress. EXCLI J. 2021; 20:922–34.Rezghi BarezSMovahedian AttarAAghaeiMMicroRNA-30c-2-3p regulates ER stress and induces apoptosis in ovarian cancer cells underlying ER stressEXCLI J20212092234Search in Google Scholar
Li D, Zhang Y, Li Y, Wang X, Wang F, Du J, et al. miR-149 suppresses the proliferation and metastasis of human gastric cancer cells by targeting FOXC1. Biomed Res Int. 2021; 2021:1503403. doi: 10.1155/2021/1503403LiDZhangYLiYWangXWangFDuJmiR-149 suppresses the proliferation and metastasis of human gastric cancer cells by targeting FOXC1Biomed Res Int20212021150340310.1155/2021/1503403Open DOISearch in Google Scholar
Guidelines Working Committee of Chinese Society of Clinical Oncology. Guidelines of Chinese Society of Clinical Oncology (CSCO). Kidney Cancer. Beijing, 2015.Guidelines Working Committee of Chinese Society of Clinical OncologyGuidelines of Chinese Society of Clinical Oncology (CSCO)Kidney CancerBeijing2015Search in Google Scholar
Zhang C, Qu Y, Xiao H, Xiao W, Liu J, Gao Y, et al. LncRNA SNHG3 promotes clear cell renal cell carcinoma proliferation and migration by upregulating TOP2A. Exp Cell Res. 2019; 384:111595. doi: 10.1016/j.yexcr.2019.111595ZhangCQuYXiaoHXiaoWLiuJGaoYLncRNA SNHG3 promotes clear cell renal cell carcinoma proliferation and migration by upregulating TOP2AExp Cell Res201938411159510.1016/j.yexcr.2019.111595Open DOISearch in Google Scholar
Abraham AD, Esquer H, Zhou Q, Tomlinson N, Hamill BD, Abbott JM, et al. Drug design targeting T-cell factor (TCF)-driven epithelial-mesenchymal transition as a therapeutic strategy for colorectal cancer. J Med Chem. 2019; 62:10182–203.AbrahamADEsquerHZhouQTomlinsonNHamillBDAbbottJMDrug design targeting T-cell factor (TCF)-driven epithelial-mesenchymal transition as a therapeutic strategy for colorectal cancerJ Med Chem20196210182203Search in Google Scholar
Ye M, He Z, Dai W, Li Z, Chen X, Liu J. A TOP2A-derived cancer panel drives cancer progression in papillary renal cell carcinoma. Oncol Lett. 2018; 16:4169–78.YeMHeZDaiWLiZChenXLiuJA TOP2A-derived cancer panel drives cancer progression in papillary renal cell carcinomaOncol Lett201816416978Search in Google Scholar
Berglund A, Amankwah EK, Kim YC, Spiess PE, Sexton WJ, Manley B, et al. Influence of gene expression on survival of clear cell renal cell carcinoma. Cancer Med. 2020; 9:8662–75.BerglundAAmankwahEKKimYCSpiessPESextonWJManleyBInfluence of gene expression on survival of clear cell renal cell carcinomaCancer Med20209866275Search in Google Scholar
Parker AS, Eckel-Passow JE, Serie D, Hilton T, Parasramka M, Joseph RW, et al. Higher expression of topoisomerase II alpha is an independent marker of increased risk of cancer-specific death in patients with clear cell renal cell carcinoma. Eur Urol. 2014; 66:929–35.ParkerASEckel-PassowJESerieDHiltonTParasramkaMJosephRWHigher expression of topoisomerase II alpha is an independent marker of increased risk of cancer-specific death in patients with clear cell renal cell carcinomaEur Urol20146692935Search in Google Scholar
Chen D, Maruschke M, Hakenberg O, Zimmermann W, Stief CG, Buchner A. TOP2A, HELLS, ATAD2, and TET3 are novel prognostic markers in renal cell carcinoma. Urology. 2017; 102:265.e1–7.ChenDMaruschkeMHakenbergOZimmermannWStiefCGBuchnerATOP2A, HELLS, ATAD2, and TET3 are novel prognostic markers in renal cell carcinomaUrology2017102265.e17Search in Google Scholar
Xiong Y, Yuan L, Chen L, Zhu Y, Zhang S, Liu X, et al. Identifying a novel biomarker TOP2A of clear cell renal cell carcinoma (ccRCC) associated with smoking by co-expression network analysis. J Cancer. 2018; 9:3912–22.XiongYYuanLChenLZhuYZhangSLiuXIdentifying a novel biomarker TOP2A of clear cell renal cell carcinoma (ccRCC) associated with smoking by co-expression network analysisJ Cancer20189391222Search in Google Scholar
Zhang F, Wu H. MiR-599 targeting TOP2A inhibits the malignancy of bladder cancer cells. Biochem Biophys Res Commun. 2021; 570:154–61.ZhangFWuHMiR-599 targeting TOP2A inhibits the malignancy of bladder cancer cellsBiochem Biophys Res Commun202157015461Search in Google Scholar
Yang Z, Liu Y, Shi C, Zhang Y, Lv R, Zhang R, et al. Suppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathways. Oncol Rep. 2017; 37:1011–9.YangZLiuYShiCZhangYLvRZhangRSuppression of PTEN/AKT signaling decreases the expression of TUBB3 and TOP2A with subsequent inhibition of cell growth and induction of apoptosis in human breast cancer MCF-7 cells via ATP and caspase-3 signaling pathwaysOncol Rep20173710119Search in Google Scholar
de Poot SA, Lai KW, van der Wal L, Plasman K, Van Damme P, Porter AC, et al. Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis. Cell Death Differ. 2014; 21:416–26.de PootSALaiKWvan der WalLPlasmanKVan DammePPorterACGranzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosisCell Death Differ20142141626Search in Google Scholar