This work is licensed under the Creative Commons Attribution 4.0 International License.
Hackam DG, Redelmeier DA. Translation of research evidence from animals to humans. JAMA 2006;296:1731–2.HackamDGRedelmeierDATranslation of research evidence from animals to humansJAMA20062961731210.1001/jama.296.14.1731Search in Google Scholar
Ledford H. Translational research: 4 ways to fix the clinical trial. Nature 2011;477:526–8.LedfordHTranslational research: 4 ways to fix the clinical trialNature2011477526810.1038/477526aSearch in Google Scholar
Jüni P, Nartey L, Reichenbach S, et al. Risk of cardiovascular events and rofecoxib: cumulative meta-analysis. Lancet 2004;364:2021–9.JüniPNarteyLReichenbachSRisk of cardiovascular events and rofecoxib: cumulative meta-analysisLancet20043642021910.1016/S0140-6736(04)17514-4Search in Google Scholar
Stolley PD. Asthma mortality. Why the United States was spared an epidemic of deaths due to asthma. Am Rev Respir Dis 1972;105:883–90.StolleyPDAsthma mortality. Why the United States was spared an epidemic of deaths due to asthmaAm Rev Respir Dis197210588390Search in Google Scholar
Schardein JL. Drugs as Teratogens 1976; CRC Press, Cleveland, Ohio; p. 49.SchardeinJLDrugs as Teratogens1976CRC PressCleveland, Ohio49Search in Google Scholar
Van Norman GA. Limitations of animal studies for predicting toxicity in clinical trials: is it time to rethink our current approach? JACC Basic Transl Sci 2019;4:845–54.Van NormanGALimitations of animal studies for predicting toxicity in clinical trials: is it time to rethink our current approach?JACC Basic Transl Sci201948455410.1016/j.jacbts.2019.10.008697855831998852Search in Google Scholar
Wolpert L. Review of „Animal models in the light of evolution” by Niall Shanks, Ph.D., and C. Ray Greek, M.D. Philos Ethics Humanit Med 2010;5:12.WolpertLReview of „Animal models in the light of evolution” by Niall Shanks, Ph.D., and C. Ray Greek, M.D.Philos Ethics Humanit Med201051210.1186/1747-5341-5-12Search in Google Scholar
Mergenthaler P, Meisel A. Animal models: value and translational potency in Principles of translational science in medicine – from bench to bedside, 2nd Ed.; Academic Press 2015; p. 83–90.MergenthalerPMeiselAAnimal models: value and translational potency in Principles of translational science in medicine – from bench to bedside2nd Ed.Academic Press2015839010.1016/B978-0-12-800687-0.00007-4Search in Google Scholar
Shim J, Al-Mashhadi RH, Sørensen CB, et al. Large animal models of atherosclerosis – new tools for persistent problems in cardiovascular medicine. J Pathol 2016;238:257–66.ShimJAl-MashhadiRHSørensenCBLarge animal models of atherosclerosis – new tools for persistent problems in cardiovascular medicineJ Pathol20162382576610.1002/path.464626414760Search in Google Scholar
Perrin S. Preclinical research: Make mouse studies work. Nature 2014;507:423–5.PerrinSPreclinical research: Make mouse studies workNature2014507423510.1038/507423a24678540Search in Google Scholar
Şerban RC, Scridon A. Data linking diabetes mellitus and atrial fibrillation-how strong is the evidence? From epidemiology and pathophysiology to therapeutic implications. Can J Cardiol 2018;34:1492–502.ŞerbanRCScridonAData linking diabetes mellitus and atrial fibrillation-how strong is the evidence? From epidemiology and pathophysiology to therapeutic implicationsCan J Cardiol201834149250210.1016/j.cjca.2018.08.01830404752Search in Google Scholar
Bebarta B, Luyten D, Heard K. Emergency medicine animal research: does use of randomization and blinding affect the results? Acad Emerg Med 2003;10:684–7.BebartaBLuytenDHeardKEmergency medicine animal research: does use of randomization and blinding affect the results?Acad Emerg Med200310684710.1111/j.1553-2712.2003.tb00056.x12782533Search in Google Scholar
Perel P, Roberts I, Sena E, W et al. Comparison of treatment effects between animal experiments and clinical trials: systematic review. BMJ 2007;334:197.PerelPRobertsISenaEWComparison of treatment effects between animal experiments and clinical trials: systematic reviewBMJ200733419710.1136/bmj.39048.407928.BE178197017175568Search in Google Scholar
Hausenloy DJ, Erik Bøtker H, Condorelli G, et al. Translating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of Cardiology. Cardiovasc Res 2013;98:7–27.HausenloyDJErik BøtkerHCondorelliGTranslating cardioprotection for patient benefit: position paper from the Working Group of Cellular Biology of the Heart of the European Society of CardiologyCardiovasc Res20139872710.1093/cvr/cvt00423334258Search in Google Scholar
Frank-Kamenetsky M, Grefhorst A, Anderson NN, et al. Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates. Proc Natl Acad Sci U S A 2008;105:11915–20.Frank-KamenetskyMGrefhorstAAndersonNNTherapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primatesProc Natl Acad Sci U S A2008105119152010.1073/pnas.0805434105257531018695239Search in Google Scholar
Ferreira GS, Veening-Griffioen DH, Boon WPC, et al. A standardised framework to identify optimal animal models for efficacy assessment in drug development. PLoS One 2019;14:e0218014.FerreiraGSVeening-GriffioenDHBoonWPCA standardised framework to identify optimal animal models for efficacy assessment in drug developmentPLoS One201914e021801410.1101/382366Search in Google Scholar