Molecular Identification of Strains within the Mycobacterium abscessus Complex and Determination of Resistance to Macrolides and Aminoglycosides

Abdalla MY, Ahmad IM, Switzer B, Britigan BE. Induction of heme oxygenase-1 contributes to survival of Mycobacterium abscessus in human macrophages-like THP-1 cells. Redox Biol. 2015; 4:328–339. https://doi.org/10.1016/j.redox.2015.01.012 Abdalla MY Ahmad IM Switzer B Britigan BE. Induction of heme oxygenase-1 contributes to survival of Mycobacterium abscessus in human macrophages-like THP-1 cells . Redox Biol . 2015 ; 4 : 328 – 339 . https://doi.org/ 10.1016/j.redox.2015.01.012 Open DOISearch in Google Scholar

Abdelaal HFM, Chan ED, Young L, Baldwin SL, Coler RN. Mycobacterium abscessus: It’s Complex. Microorganisms. 2022 Jul; 10(7):1454. https://doi.org/10.3390/microorganisms10071454 Abdelaal HFM Chan ED Young L Baldwin SL Coler RN. Mycobacterium abscessus: It’s Complex . Microorganisms . 2022 Jul ; 10 ( 7 ): 1454 . https://doi.org/ 10.3390/microorganisms10071454 Open DOISearch in Google Scholar

Bastian S, Veziris N, Roux AL, Brossier F, Gaillard JL, Jarlier V, Cambau E. Assessment of clarithromycin susceptibility in strains belonging to the Mycobacterium abscessus group by erm(41) and rrl sequencing. Antimicrob Agents Chemother. 2011 Feb;55(2):775–781. https://doi.org/10.1128/AAC.00861-10 Bastian S Veziris N Roux AL Brossier F Gaillard JL Jarlier V Cambau E. Assessment of clarithromycin susceptibility in strains belonging to the Mycobacterium abscessus group by erm(41) and rrl sequencing . Antimicrob Agents Chemother . 2011 Feb ; 55 ( 2 ): 775 – 781 . https://doi.org/ 10.1128/AAC.00861-10 Open DOISearch in Google Scholar

Bernut A, Viljoen A, Dupont C, Sapriel G, Blaise M, Bouchier C, Brosch R, de Chastellier C, Herrmann JL, Kremer L. Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members. Mol Microbiol. 2016 Mar;99(5):866–883. https://doi.org/10.1111/mmi.13283 Bernut A Viljoen A Dupont C Sapriel G Blaise M Bouchier C Brosch R de Chastellier C Herrmann JL Kremer L. Insights into the smooth-to-rough transitioning in Mycobacterium bolletii unravels a functional Tyr residue conserved in all mycobacterial MmpL family members . Mol Microbiol . 2016 Mar ; 99 ( 5 ): 866 – 883 . https://doi.org/ 10.1111/mmi.13283 Open DOISearch in Google Scholar

Boeck L, Burbaud S, Skwark M, Pearson WH, Sangen J, Wuest AW, Marshall EKP, Weimann A, Everall I, Bryant JM, et al. Mycobacterium abscessus pathogenesis identified by phenogenomic analyses. Nat Microbiol. 2022 Sep;7(9):1431–1441. https://doi.org/10.1038/s41564-022-01204-x Boeck L Burbaud S Skwark M Pearson WH Sangen J Wuest AW Marshall EKP Weimann A Everall I Bryant JM . Mycobacterium abscessus pathogenesis identified by phenogenomic analyses . Nat Microbiol . 2022 Sep ; 7 ( 9 ): 1431 – 1441 . https://doi.org/ 10.1038/s41564-022-01204-x Open DOISearch in Google Scholar

Broncano-Lavado A, Senhaji-Kacha A, Santamaría-Corral G, Esteban J, García-Quintanilla M. Alternatives to antibiotics against Mycobacterium abscessus. Antibiotics. 2022 Sep;11(10):1322. https://doi.org/10.3390/antibiotics11101322 Broncano-Lavado A Senhaji-Kacha A Santamaría-Corral G Esteban J García-Quintanilla M. Alternatives to antibiotics against Mycobacterium abscessus . Antibiotics . 2022 Sep ; 11 ( 10 ): 1322 . https://doi.org/ 10.3390/antibiotics11101322 Open DOISearch in Google Scholar

Brown-Elliott BA, Wallace RJ Jr. Clinical and taxonomic status of pathogenic nonpigmented or late-pigmenting rapidly growing mycobacteria. Clin Microbiol Rev. 2002 Oct;15(4):716–746. https://doi.org/10.1128/CMR.15.4.716-746.2002 Brown-Elliott BA Wallace RJ Jr . Clinical and taxonomic status of pathogenic nonpigmented or late-pigmenting rapidly growing mycobacteria . Clin Microbiol Rev . 2002 Oct ; 15 ( 4 ): 716 – 746 . https://doi.org/ 10.1128/CMR.15.4.716-746.2002 Open DOISearch in Google Scholar

Cho YJ, Yi H, Chun J, Cho SN, Daley CL, Koh WJ, Shin SJ. The genome sequence of ‘Mycobacterium massiliense’ strain CIP 108297 suggests the independent taxonomic status of the Mycobacterium abscessus complex at the subspecies level. PLoS One. 2013 Nov; 8(11):e81560. https://doi.org/10.1371/journal.pone.0081560 Cho YJ Yi H Chun J Cho SN Daley CL Koh WJ Shin SJ. The genome sequence of ‘Mycobacterium massiliense’ strain CIP 108297 suggests the independent taxonomic status of the Mycobacterium abscessus complex at the subspecies level . PLoS One . 2013 Nov ; 8 ( 11 ) :e81560. https://doi.org/ 10.1371/journal.pone.0081560 Open DOISearch in Google Scholar

Choi H, Kim SY, Kim DH, Huh HJ, Ki CS, Lee NY, Lee SH, Shin S, Shin SJ, Daley CL, et al. Clinical characteristics and treatment outcomes of patients with acquired macrolide-resistant Mycobacterium abscessus lung disease. Antimicrob Agents Chemother. 2017 Sep;61(10):e01146–17. https://doi.org/10.1128/AAC.01146-17 Choi H Kim SY Kim DH Huh HJ Ki CS Lee NY Lee SH Shin S Shin SJ Daley CL . Clinical characteristics and treatment outcomes of patients with acquired macrolide-resistant Mycobacterium abscessus lung disease . Antimicrob Agents Chemother . 2017 Sep ; 61 ( 10 ) :e01146–17. https://doi.org/ 10.1128/AAC.01146-17 Open DOISearch in Google Scholar

Choo SW, Wee WY, Ngeow YF, Mitchell W, Tan JL, Wong GJ, Zhao Y, Xiao J. Genomic reconnaissance of clinical isolates of emerging human pathogen Mycobacterium abscessus reveals high evolutionary potential. Sci Rep. 2014 Feb;4:4061. https://doi.org/10.1038/srep04061 Choo SW Wee WY Ngeow YF Mitchell W Tan JL Wong GJ Zhao Y Xiao J. Genomic reconnaissance of clinical isolates of emerging human pathogen Mycobacterium abscessus reveals high evolutionary potential . Sci Rep . 2014 Feb ; 4 : 4061 . https://doi.org/ 10.1038/srep04061 Open DOISearch in Google Scholar

CLSI. Performance standards for susceptibility testing of mycobacteria, Nocardia spp., and other aerobic actinomycetes. 1st ed. CLSI supplement M62. Wayne (USA): Clinical and Laboratory Standards Institute; 2018b. CLSI . Performance standards for susceptibility testing of mycobacteria, Nocardia spp., and other aerobic actinomycetes . 1^st ed . CLSI supplement M62. Wayne (USA) : Clinical and Laboratory Standards Institute ; 2018b . Search in Google Scholar

CLSI. Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic actinomycetes. 3rd ed. CLSI standard M24. Wayne (USA): Clinical and Laboratory Standards Institute; 2018a. CLSI . Susceptibility testing of mycobacteria, Nocardia spp., and other aerobic actinomycetes . 3^rd ed . CLSI standard M24. Wayne (USA) : Clinical and Laboratory Standards Institute ; 2018a . Search in Google Scholar

da Silva PE, Von Groll A, Martin A, Palomino JC. Efflux as a mechanism for drug resistance in Mycobacterium tuberculosis. FEMS Immunol Med Microbiol. 2011 Oct;63(1):1–9. https://doi.org/10.1111/j.1574-695X.2011.00831.x da Silva PE Von Groll A Martin A Palomino JC. Efflux as a mechanism for drug resistance in Mycobacterium tuberculosis . FEMS Immunol Med Microbiol . 2011 Oct ; 63 ( 1 ): 1 – 9 . https://doi.org/ 10.1111/j.1574-695X.2011.00831.x Open DOISearch in Google Scholar

Daley CL, Iaccarino JM, Lange C, Cambau E, Wallace RJ Jr, Andrejak C, Böttger EC, Brozek J, Griffith DE, Guglielmetti L, et al. Treatment of nontuberculous mycobacterial pulmonary disease: An official ATS/ERS/ESCMID/IDSA clinical practice guideline. Eur Respir J. 2020 Jul;56(1):2000535. https://doi.org/10.1183/13993003.00535-2020 Daley CL Iaccarino JM Lange C Cambau E Wallace RJ Jr Andrejak C Böttger EC Brozek J Griffith DE Guglielmetti L . Treatment of nontuberculous mycobacterial pulmonary disease: An official ATS/ERS/ESCMID/IDSA clinical practice guideline . Eur Respir J . 2020 Jul ; 56 ( 1 ): 2000535 . https://doi.org/ 10.1183/13993003.00535-2020 Open DOISearch in Google Scholar

Degiacomi G, Sammartino JC, Chiarelli LR, Riabova O, Makarov V, Pasca MR. Mycobacterium abscessus, an emerging and worrisome pathogen among cystic fibrosis patients. Int J Mol Sci. 2019 Nov; 20(23):5868. https://doi.org/10.3390/ijms20235868 Degiacomi G Sammartino JC Chiarelli LR Riabova O Makarov V Pasca MR. Mycobacterium abscessus, an emerging and worrisome pathogen among cystic fibrosis patients . Int J Mol Sci . 2019 Nov ; 20 ( 23 ): 5868 . https://doi.org/ 10.3390/ijms20235868 Open DOISearch in Google Scholar

Esther CR Jr, Esserman DA, Gilligan P, Kerr A, Noone PG. Chronic Mycobacterium abscessus infection and lung function decline in cystic fibrosis. J Cyst Fibros. 2010 Mar;9(2):117–123. https://doi.org/10.1016/j.jcf.2009.12.001 Esther CR Jr Esserman DA Gilligan P Kerr A Noone PG. Chronic Mycobacterium abscessus infection and lung function decline in cystic fibrosis . J Cyst Fibros . 2010 Mar ; 9 ( 2 ): 117 – 123 . https://doi.org/ 10.1016/j.jcf.2009.12.001 Open DOISearch in Google Scholar

Floto RA, Olivier KN, Saiman L, Daley CL, Herrmann JL, Nick JA, Noone PG, Bilton D, Corris P, Gibson RL, et al.; US Cystic Fibrosis Foundation and European Cystic Fibrosis Society. US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis. Thorax. 2016 Jan;71(Suppl 1): i1–22. https://doi.org/10.1136/thoraxjnl-2015-207360 Floto RA Olivier KN Saiman L Daley CL Herrmann JL Nick JA Noone PG Bilton D Corris P Gibson RL US Cystic Fibrosis Foundation and European Cystic Fibrosis Society .; . US Cystic Fibrosis Foundation and European Cystic Fibrosis Society consensus recommendations for the management of non-tuberculous mycobacteria in individuals with cystic fibrosis . Thorax . 2016 Jan ; 71 (Suppl 1): i1–22. https://doi.org/ 10.1136/thoraxjnl-2015-207360 Open DOISearch in Google Scholar

GenoType NTM-DR. Molecular genetic assay for detection of resistance to macrolides and aminoglycosides in various nontuberculous mycobacterial species (NTM) from cultured material. Geno-Type NTM-DR VER 1.0 Instructions for use (IFU-297-03). Nehren (Germany): Hain Lifescience GmbH; 2015. p. 4–9. GenoType NTM-DR . Molecular genetic assay for detection of resistance to macrolides and aminoglycosides in various nontuberculous mycobacterial species (NTM) from cultured material . Geno-Type NTM-DR VER 1.0 Instructions for use (IFU-297-03). Nehren (Germany) : Hain Lifescience GmbH ; 2015 . p. 4 – 9 . Search in Google Scholar

Harada T, Akiyama Y, Kurashima A, Nagai H, Tsuyuguchi K, Fujii T, Yano S, Shigeto E, Kuraoka T, Kajiki A, et al. Clinical and microbiological differences between Mycobacterium abscessus and Mycobacterium massiliense lung diseases. J Clin Microbiol. 2012 Nov;50(11):3556–3561. https://doi.org/10.1128/JCM.01175-12 Harada T Akiyama Y Kurashima A Nagai H Tsuyuguchi K Fujii T Yano S Shigeto E Kuraoka T Kajiki A . Clinical and microbiological differences between Mycobacterium abscessus and Mycobacterium massiliense lung diseases . J Clin Microbiol . 2012 Nov ; 50 ( 11 ): 3556 – 3561 . https://doi.org/ 10.1128/JCM.01175-12 Open DOISearch in Google Scholar

Hoefsloot W, van Ingen J, Andrejak C, Angeby K, Bauriaud R, Bemer P, Beylis N, Boeree MJ, Cacho J, Chihota V, et al.; Non-tuberculous Mycobacteria Network European Trials Group. The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: An NTM-NET collaborative study. Eur Respir J. 2013 Dec;42(6):1604–1613. https://doi.org/10.1183/09031936.00149212 Hoefsloot W van Ingen J Andrejak C Angeby K Bauriaud R Bemer P Beylis N Boeree MJ Cacho J Chihota V Non-tuberculous Mycobacteria Network European Trials Group .; . The geographic diversity of nontuberculous mycobacteria isolated from pulmonary samples: An NTM-NET collaborative study . Eur Respir J . 2013 Dec ; 42 ( 6 ): 1604 – 1613 . https://doi.org/ 10.1183/09031936.00149212 Open DOISearch in Google Scholar

Honda JR, Virdi R, Chan ED. Global environmental nontuberculous mycobacteria and their contemporaneous man-made and natural niches. Front Microbiol. 2018 Aug;9:2029. https://doi.org/10.3389/fmicb.2018.02029 Honda JR Virdi R Chan ED. Global environmental nontuberculous mycobacteria and their contemporaneous man-made and natural niches . Front Microbiol . 2018 Aug ; 9 : 2029 . https://doi.org/ 10.3389/fmicb.2018.02029 Open DOISearch in Google Scholar

Howard ST. Recent progress towards understanding genetic variation in the Mycobacterium abscessus complex. Tuberculosis. 2013 Dec;93(Suppl):S15–S20. https://doi.org/10.1016/S1472-9792(13)70005-2 Howard ST. Recent progress towards understanding genetic variation in the Mycobacterium abscessus complex . Tuberculosis . 2013 Dec ; 93 (Suppl):S15–S20. https://doi.org/ 10.1016/S1472-9792(13)70005-2 Open DOISearch in Google Scholar

ISO 20776-1:2019. Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices. Part 1: Broth micro-dilution reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases. Geneva (Switzerland): International Organization for Standardization; 2019. ISO 20776-1:2019 . Susceptibility testing of infectious agents and evaluation of performance of antimicrobial susceptibility test devices . Part 1: Broth micro-dilution reference method for testing the in vitro activity of antimicrobial agents against rapidly growing aerobic bacteria involved in infectious diseases . Geneva (Switzerland) : International Organization for Standardization ; 2019 . Search in Google Scholar

Jang MA, Koh WJ, Huh HJ, Kim SY, Jeon K, Ki CS, Lee NY. Distribution of nontuberculous mycobacteria by multigene sequencebased typing and clinical significance of isolated strains. J Clin Microbiol. 2014 Apr;52(4):1207–1212. https://doi.org/10.1128/JCM.03053-13 Jang MA Koh WJ Huh HJ Kim SY Jeon K Ki CS Lee NY. Distribution of nontuberculous mycobacteria by multigene sequencebased typing and clinical significance of isolated strains . J Clin Microbiol . 2014 Apr ; 52 ( 4 ): 1207 – 1212 . https://doi.org/ 10.1128/JCM.03053-13 Open DOISearch in Google Scholar

Jönsson BE, Gilljam M, Lindblad A, Ridell M, Wold AE, Welinder-Olsson C. Molecular epidemiology of Mycobacterium abscessus, with focus on cystic fibrosis. J Clin Microbiol. 2007 May; 45(5):1497–1504. https://doi.org/10.1128/JCM.02592-06 Jönsson BE Gilljam M Lindblad A Ridell M Wold AE Welinder-Olsson C. Molecular epidemiology of Mycobacterium abscessus, with focus on cystic fibrosis . J Clin Microbiol . 2007 May ; 45 ( 5 ): 1497 – 1504 . https://doi.org/ 10.1128/JCM.02592-06 Open DOISearch in Google Scholar

Kalaiarasan E, Thangavelu K, Krishnapriya K, Muthuraj M, Jose M, Joseph NM. Diagnostic performance of real time PCR and MALDI-TOF in the detection of nontuberculous mycobacteria from clinical isolates. Tuberculosis. 2020 Dec;125:101988. https://doi.org/10.1016/j.tube.2020.101988 Kalaiarasan E Thangavelu K Krishnapriya K Muthuraj M Jose M Joseph NM. Diagnostic performance of real time PCR and MALDI-TOF in the detection of nontuberculous mycobacteria from clinical isolates . Tuberculosis . 2020 Dec ; 125 : 101988 . https://doi.org/ 10.1016/j.tube.2020.101988 Open DOISearch in Google Scholar

Kam JY, Hortle E, Krogman E, Warner SE, Wright K, Luo K, Cheng T, Manuneedhi Cholan P, Kikuchi K, Triccas JA, et al. Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish. Nat Commun. 2022 Feb 17;13(1):952. https://doi.org/10.1038/s41467-022-28638-5 Kam JY Hortle E Krogman E Warner SE Wright K Luo K Cheng T Manuneedhi Cholan P Kikuchi K Triccas JA . Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish . Nat Commun . 2022 Feb 17 ; 13 ( 1 ): 952 . https://doi.org/ 10.1038/s41467-022-28638-5 Open DOISearch in Google Scholar

Kavaliunaite E, Harris KA, Aurora P, Dixon G, Shingadia D, Muthialu N, Spencer H. Outcome according to subspecies following lung transplantation in cystic fibrosis pediatric patients infected with Mycobacterium abscessus. Transpl Infect Dis. 2020 Jun; 22(3):e13274. https://doi.org/10.1111/tid.13274 Kavaliunaite E Harris KA Aurora P Dixon G Shingadia D Muthialu N Spencer H. Outcome according to subspecies following lung transplantation in cystic fibrosis pediatric patients infected with Mycobacterium abscessus . Transpl Infect Dis . 2020 Jun ; 22 ( 3 ) :e13274. https://doi.org/ 10.1111/tid.13274 Open DOISearch in Google Scholar

Koh WJ, Jeon K, Lee NY, Kim BJ, Kook YH, Lee SH, Park YK, Kim CK, Shin SJ, Huitt GA, et al. Clinical significance of differentiation of Mycobacterium massiliense from Mycobacterium abscessus. Am J Respir Crit Care Med. 2011 Feb;183(3):405–410. https://doi.org/10.1164/rccm.201003-0395OC Koh WJ Jeon K Lee NY Kim BJ Kook YH Lee SH Park YK Kim CK Shin SJ Huitt GA . Clinical significance of differentiation of Mycobacterium massiliense from Mycobacterium abscessus . Am J Respir Crit Care Med . 2011 Feb ; 183 ( 3 ): 405 – 410 . https://doi.org/ 10.1164/rccm.201003-0395OC Open DOISearch in Google Scholar

Leao SC, Tortoli E, Viana-Niero C, Ueki SY, Lima KV, Lopes ML, Yubero J, Menendez MC, Garcia MJ. Characterization of mycobacteria from a major Brazilian outbreak suggests that revision of the taxonomic status of members of the Mycobacterium chelonae-M. abscessus group is needed. J Clin Microbiol. 2009 Sep;47(9):2691–2698. https://doi.org/10.1128/JCM.00808-09 Leao SC Tortoli E Viana-Niero C Ueki SY Lima KV Lopes ML Yubero J Menendez MC Garcia MJ. Characterization of mycobacteria from a major Brazilian outbreak suggests that revision of the taxonomic status of members of the Mycobacterium chelonae-M. abscessus group is needed . J Clin Microbiol . 2009 Sep ; 47 ( 9 ): 2691 – 2698 . https://doi.org/ 10.1128/JCM.00808-09 Open DOISearch in Google Scholar

Leard LE, Holm AM, Valapour M, Glanville AR, Attawar S, Aversa M, Campos SV, Christon LM, Cypel M, Dellgren G, et al. Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation. J Heart Lung Transplant. 2021 Nov;40(11):1349–1379. https://doi.org/10.1016/j.healun.2021.07.005 Leard LE Holm AM Valapour M Glanville AR Attawar S Aversa M Campos SV Christon LM Cypel M Dellgren G . Consensus document for the selection of lung transplant candidates: An update from the International Society for Heart and Lung Transplantation . J Heart Lung Transplant . 2021 Nov ; 40 ( 11 ): 1349 – 1379 . https://doi.org/ 10.1016/j.healun.2021.07.005 Open DOISearch in Google Scholar

Li H, Mulati G, Shang Y, Yao C, Wang Y, Ren W, Xue Z, Li S, Pang Y. Rapid detection of clarithromycin and amikacin resistance in Mycobacterium abscessus complex by high-resolution melting curve analysis. Microbiol Spectr. 2022 Jun;10(3):e0057422. https://doi.org/10.1128/spectrum.00574-22 Li H Mulati G Shang Y Yao C Wang Y Ren W Xue Z Li S Pang Y. Rapid detection of clarithromycin and amikacin resistance in Mycobacterium abscessus complex by high-resolution melting curve analysis . Microbiol Spectr . 2022 Jun ; 10 ( 3 ) :e0057422. https://doi.org/ 10.1128/spectrum.00574-22 Open DOISearch in Google Scholar

Luo L, Li B, Chu H, Huang D, Zhang Z, Zhang J, Gui T, Xu L, Zhao L, Sun X, et al. Characterization of Mycobacterium Abscessus subtypes in Shanghai of China: Drug sensitivity and bacterial epidemicity as well as clinical manifestations. Medicine (Baltimore). 2016 Jan;95(3):e2338. https://doi.org/10.1097/MD.0000000000002338 Luo L Li B Chu H Huang D Zhang Z Zhang J Gui T Xu L Zhao L Sun X . Characterization of Mycobacterium Abscessus subtypes in Shanghai of China: Drug sensitivity and bacterial epidemicity as well as clinical manifestations . Medicine (Baltimore) . 2016 Jan ; 95 ( 3 ) :e2338. https://doi.org/ 10.1097/MD.0000000000002338 Open DOISearch in Google Scholar

Luthra S, Rominski A, Sander P. The role of antibiotic-target-modifying and antibiotic-modifying enzymes in Mycobacterium abscessus drug resistance. Front Microbiol. 2018 Sep;9:2179. https://doi.org/10.3389/fmicb.2018.02179 Luthra S Rominski A Sander P. The role of antibiotic-target-modifying and antibiotic-modifying enzymes in Mycobacterium abscessus drug resistance . Front Microbiol . 2018 Sep ; 9 : 2179 . https://doi.org/ 10.3389/fmicb.2018.02179 Open DOISearch in Google Scholar

Mase A, Yamaguchi F, Funaki T, Yamazaki Y, Shikama Y, Fukuchi K. PCR amplification of the erm(41) gene can be used to predict the sensitivity of Mycobacterium abscessus complex strains to clarithromycin. Exp Ther Med. 2020 Feb;19(2):945–955. https://doi.org/10.3892/etm.2019.8289 Mase A Yamaguchi F Funaki T Yamazaki Y Shikama Y Fukuchi K. PCR amplification of the erm(41) gene can be used to predict the sensitivity of Mycobacterium abscessus complex strains to clarithromycin . Exp Ther Med . 2020 Feb ; 19 ( 2 ): 945 – 955 . https://doi.org/ 10.3892/etm.2019.8289 Open DOISearch in Google Scholar

Medjahed H, Gaillard JL, Reyrat JM. Mycobacterium abscessus: A new player in the mycobacterial field. Trends Microbiol. 2010 Mar;18(3):117–123. https://doi.org/10.1016/j.tim.2009.12.007 Medjahed H Gaillard JL Reyrat JM. Mycobacterium abscessus: A new player in the mycobacterial field . Trends Microbiol . 2010 Mar ; 18 ( 3 ): 117 – 123 . https://doi.org/ 10.1016/j.tim.2009.12.007 Open DOISearch in Google Scholar

Medjahed H, Reyrat JM. Construction of Mycobacterium abscessus defined glycopeptidolipid mutants: Comparison of genetic tools. Appl Environ Microbiol. 2009 Mar;75(5):1331–1338. https://doi.org/10.1128/AEM.01914-08 Medjahed H Reyrat JM. Construction of Mycobacterium abscessus defined glycopeptidolipid mutants: Comparison of genetic tools . Appl Environ Microbiol . 2009 Mar ; 75 ( 5 ): 1331 – 1338 . https://doi.org/ 10.1128/AEM.01914-08 Open DOISearch in Google Scholar

Meehan CJ, Barco RA, Loh YE, Cogneau S, Rigouts L. Reconstituting the genus Mycobacterium. Int J Syst Evol Microbiol. 2021 Sep;71(9):004922. https://doi.org/10.1099/ijsem.0.004922 Meehan CJ Barco RA Loh YE Cogneau S Rigouts L. Reconstituting the genus Mycobacterium . Int J Syst Evol Microbiol . 2021 Sep ; 71 ( 9 ) :004922. https://doi.org/ 10.1099/ijsem.0.004922 Open DOISearch in Google Scholar

Mudde SE, Schildkraut JA, Ammerman NC, de Vogel CP, de Steenwinkel JEM, van Ingen J, Bax HI. Unraveling antibiotic resistance mechanisms in Mycobacterium abscessus: The potential role of efflux pumps. J Glob Antimicrob Resist. 2022 Dec;31:345–352. https://doi.org/10.1016/j.jgar.2022.10.015 Mudde SE Schildkraut JA Ammerman NC de Vogel CP de Steenwinkel JEM van Ingen J Bax HI. Unraveling antibiotic resistance mechanisms in Mycobacterium abscessus: The potential role of efflux pumps . J Glob Antimicrob Resist . 2022 Dec ; 31 : 345 – 352 . https://doi.org/ 10.1016/j.jgar.2022.10.015 Open DOISearch in Google Scholar

Nash KA, Brown-Elliott BA, Wallace RJ Jr. A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae. Antimicrob Agents Chemother. 2009 Apr;53(4):1367–1376. https://doi.org/10.1128/AAC.01275-08 Nash KA Brown-Elliott BA Wallace RJ Jr . A novel gene, erm(41), confers inducible macrolide resistance to clinical isolates of Mycobacterium abscessus but is absent from Mycobacterium chelonae . Antimicrob Agents Chemother . 2009 Apr ; 53 ( 4 ): 1367 – 1376 . https://doi.org/ 10.1128/AAC.01275-08 Open DOISearch in Google Scholar

Nessar R, Reyrat JM, Murray A, Gicquel B. Genetic analysis of new 16S rRNA mutations conferring aminoglycoside resistance in Mycobacterium abscessus. J Antimicrob Chemother. 2011 Aug; 66(8):1719–1724. https://doi.org/10.1093/jac/dkr209 Nessar R Reyrat JM Murray A Gicquel B. Genetic analysis of new 16S rRNA mutations conferring aminoglycoside resistance in Mycobacterium abscessus . J Antimicrob Chemother . 2011 Aug ; 66 ( 8 ): 1719 – 1724 . https://doi.org/ 10.1093/jac/dkr209 Open DOISearch in Google Scholar

Nishiuchi Y, Iwamoto T, Maruyama F. Infection sources of a common non-tuberculous mycobacterial pathogen, Mycobacterium avium complex. Front Med (Lausanne). 2017 Mar;4:27. Published 2017 Mar 7. https://doi.org/10.3389/fmed.2017.00027 Nishiuchi Y Iwamoto T Maruyama F. Infection sources of a common non-tuberculous mycobacterial pathogen, Mycobacterium avium complex . Front Med (Lausanne) . 2017 Mar ; 4 : 27 . Published 2017 Mar 7 . https://doi.org/ 10.3389/fmed.2017.00027 Open DOISearch in Google Scholar

Qvist T, Gilljam M, Jönsson B, Taylor-Robinson D, Jensen-Fangel S, Wang M, Svahn A, Kötz K, Hansson L, Hollsing A, et al.; Scandinavian Cystic Fibrosis Study Consortium (SCFSC). Epidemiology of nontuberculous mycobacteria among patients with cystic fibrosis in Scandinavia. J Cyst Fibros. 2015 Jan;14(1):46–52. https://doi.org/10.1016/j.jcf.2014.08.002 Qvist T Gilljam M Jönsson B Taylor-Robinson D Jensen-Fangel S Wang M Svahn A Kötz K Hansson L Hollsing A Scandinavian Cystic Fibrosis Study Consortium (SCFSC) .;. Epidemiology of nontuberculous mycobacteria among patients with cystic fibrosis in Scandinavia . J Cyst Fibros . 2015 Jan ; 14 ( 1 ): 46 – 52 . https://doi.org/ 10.1016/j.jcf.2014.08.002 Open DOISearch in Google Scholar

Qvist T, Pressler T, Høiby N, Katzenstein TL. Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis. Respir Res. 2014 Apr;15(1):41. https://doi.org/10.1186/1465-9921-15-41 Qvist T Pressler T Høiby N Katzenstein TL. Shifting paradigms of nontuberculous mycobacteria in cystic fibrosis . Respir Res . 2014 Apr ; 15 ( 1 ): 41 . https://doi.org/ 10.1186/1465-9921-15-41 Open DOISearch in Google Scholar

Rollet-Cohen V, Roux AL, Le Bourgeois M, Sapriel G, El Bahri M, Jais JP, Heym B, Mougari F, Raskine L, Véziris N, et al. Mycobacterium bolletii lung disease in cystic fibrosis. Chest. 2019 Aug;156(2): 247–254. https://doi.org/10.1016/j.chest.2019.03.019 Rollet-Cohen V Roux AL Le Bourgeois M Sapriel G El Bahri M Jais JP Heym B Mougari F Raskine L Véziris N . Mycobacterium bolletii lung disease in cystic fibrosis . Chest . 2019 Aug ; 156 ( 2 ): 247 – 254 . https://doi.org/ 10.1016/j.chest.2019.03.019 Open DOISearch in Google Scholar

Roux AL, Catherinot E, Soismier N, Heym B, Bellis G, Lemonnier L, Chiron R, Fauroux B, Le Bourgeois M, Munck A, et al.; OMA group. Comparing Mycobacterium massiliense and Mycobacterium abscessus lung infections in cystic fibrosis patients. J Cyst Fibros. 2015 Jan;14(1):63–69. https://doi.org/10.1016/j.jcf.2014.07.004 Roux AL Catherinot E Soismier N Heym B Bellis G Lemonnier L Chiron R Fauroux B Le Bourgeois M Munck A OMA group .; . Comparing Mycobacterium massiliense and Mycobacterium abscessus lung infections in cystic fibrosis patients . J Cyst Fibros . 2015 Jan ; 14 ( 1 ): 63 – 69 . https://doi.org/ 10.1016/j.jcf.2014.07.004 Open DOISearch in Google Scholar

Roux AL, Viljoen A, Bah A, Simeone R, Bernut A, Laencina L, Deramaudt T, Rottman M, Gaillard JL, Majlessi L, et al. The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages. Open Biol. 2016 Nov;6(11):160185. https://doi.org/10.1098/rsob.160185 Roux AL Viljoen A Bah A Simeone R Bernut A Laencina L Deramaudt T Rottman M Gaillard JL Majlessi L . The distinct fate of smooth and rough Mycobacterium abscessus variants inside macrophages . Open Biol . 2016 Nov ; 6 ( 11 ): 160185 . https://doi.org/ 10.1098/rsob.160185 Open DOISearch in Google Scholar

Schiff HF, Jones S, Achaiah A, Pereira A, Stait G, Green B. Clinical relevance of non-tuberculous mycobacteria isolated from respiratory specimens: seven year experience in a UK hospital. Sci Rep. 2019 Feb;9(1):1730. https://doi.org/10.1038/s41598-018-37350-8 Schiff HF Jones S Achaiah A Pereira A Stait G Green B. Clinical relevance of non-tuberculous mycobacteria isolated from respiratory specimens: seven year experience in a UK hospital . Sci Rep . 2019 Feb ; 9 ( 1 ): 1730 . https://doi.org/ 10.1038/s41598-018-37350-8 Open DOISearch in Google Scholar

Soroka D, Dubée V, Soulier-Escrihuela O, Cuinet G, Hugonnet JE, Gutmann L, Mainardi JL, Arthur M. Characterization of broadspectrum Mycobacterium abscessus class A β-lactamase. J Antimicrob Chemother. 2014 Mar;69(3):691–696. https://doi.org/10.1093/jac/dkt410 Soroka D Dubée V Soulier-Escrihuela O Cuinet G Hugonnet JE Gutmann L Mainardi JL Arthur M. Characterization of broadspectrum Mycobacterium abscessus class A β-lactamase . J Antimicrob Chemother . 2014 Mar ; 69 ( 3 ): 691 – 696 . https://doi.org/ 10.1093/jac/dkt410 Open DOISearch in Google Scholar

Stout JE, Koh WJ, Yew WW. Update on pulmonary disease due to non-tuberculous mycobacteria. Int J Infect Dis. 2016 Apr;45:123–134. https://doi.org/10.1016/j.ijid.2016.03.006 Stout JE Koh WJ Yew WW. Update on pulmonary disease due to non-tuberculous mycobacteria . Int J Infect Dis . 2016 Apr ; 45 : 123 – 134 . https://doi.org/ 10.1016/j.ijid.2016.03.006 Open DOISearch in Google Scholar

Victoria L, Gupta A, Gómez JL, Robledo J. Mycobacterium abscessus complex: A review of recent developments in an emerging pathogen. Front Cell Infect Microbiol. 2021 Apr;11:659997. https://doi.org/10.3389/fcimb.2021.659997 Victoria L Gupta A Gómez JL Robledo J. Mycobacterium abscessus complex: A review of recent developments in an emerging pathogen . Front Cell Infect Microbiol . 2021 Apr ; 11 : 659997 . https://doi.org/ 10.3389/fcimb.2021.659997 Open DOISearch in Google Scholar

Wallace RJ Jr, Meier A, Brown BA, Zhang Y, Sander P, Onyi GO, Böttger EC. Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus. Antimicrob Agents Chemother. 1996 Jul;40(7):1676–1681. https://doi.org/10.1128/AAC.40.7.1676 Wallace RJ Jr Meier A Brown BA Zhang Y Sander P Onyi GO Böttger EC. Genetic basis for clarithromycin resistance among isolates of Mycobacterium chelonae and Mycobacterium abscessus . Antimicrob Agents Chemother . 1996 Jul ; 40 ( 7 ): 1676 – 1681 . https://doi.org/ 10.1128/AAC.40.7.1676 Open DOISearch in Google Scholar

Wassilew N, Hoffmann H, Andrejak C, Lange C. Pulmonary disease caused by non-tuberculous mycobacteria. Respiration. 2016; 91(5):386–402. https://doi.org/10.1159/000445906 Wassilew N Hoffmann H Andrejak C Lange C. Pulmonary disease caused by non-tuberculous mycobacteria . Respiration . 2016 ; 91 ( 5 ): 386 – 402 . https://doi.org/ 10.1159/000445906 Open DOISearch in Google Scholar