Longitudinal monitoring of Apparent Diffusion Coefficient (ADC) in patients with prostate cancer undergoing MR-guided radiotherapy on an MR-Linac at 1.5 T: a prospective feasibility study
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FIGURE 1.
Flow diagram illustrating the inclusion/exclusion process.
FIGURE 2.
T2-weighted MR images (scan time: 2 minutes) and apparent diffusion coefficient (ADC) maps of a 66-year-old male patient with prostate cancer in the antero-apical region of the transition zone (red arrows) at baseline (left column) and during radiotherapy (right column) as recorded on MR-Linac (MRL) and on standard MRI at 3T (MRI3T). The figure shows similar dynamics of lesion ADC elevation during radiotherapy.
FIGURE 3.
Scatter plots with a fitted line for ADC values as recorded on MR-Linac and MRI3T for reader 1. (A) at baseline, (B) during radiotherapy (week 2). These plots illustrate the strong positive correlation between MRL-ADC and MRI3T-ADC at both time points.