[
1. Alamzadeh Z, Beik J, Mirrahimi M, et al. Gold nanoparticles promote a multimodal synergistic cancer therapy strategy by co-delivery of thermo-chemo-radio therapy. Eur J Pharm Sci. 2020;145(105235):1-8. https://doi.org/10.1016/j.ejps.2020.10523510.1016/j.ejps.2020.10523531991226
]Search in Google Scholar
[
2. Ahmad R, Schettino G, Royle G, et al. Radiobiological Implications of Nanoparticles Following Radiation Treatment. Part Part Syst Charact. 2020;1900411. https://doi.org/10.1002/ppsc.20190041110.1002/ppsc.201900411842746834526737
]Search in Google Scholar
[
3. Igaz N, Szőke K, Kovács D, et al. Synergistic radiosensitization by gold nanoparticles and the histone deacetylase inhibitor SAHA in 2D and 3D cancer cell cultures. Nanomaterials. 2020;10(1). https://doi.org/10.3390/nano1001015810.3390/nano10010158702303031963267
]Search in Google Scholar
[
4. Moradi F, Rezaee Ebrahim Saraee K, Abdul Sani SF, Bradley DA. Metallic nanoparticle radiosensitization: The role of Monte Carlo simulations towards progress. Radiat Phys Chem. 2021;180(109294). https://doi.org/10.1016/j.radphyschem.2020.10929410.1016/j.radphyschem.2020.109294
]Search in Google Scholar
[
5. Cunningham C. Radiosensitization Effects of Gold Nanoparticles in Proton Therapy. Msc. Published online 2017.
]Search in Google Scholar
[
6. Yang C, Bromma K, Sung W, Schuemann J, Chithrani D. Determining the radiation enhancement effects of gold nanoparticles in cells in a combined treatment with cisplatin and radiation at therapeutic megavoltage energies. Cancers (Basel). 2018;10(150):1-16. https://doi.org/10.3390/cancers1005015010.3390/cancers10050150597712329786642
]Search in Google Scholar
[
7. Rahman WNWA, Rashid RA, Muhammad M, Dollah N, Razak KA, Geso M. Dose Enhancement by Different Size of Gold Nanoparticles Under Irradiation of Megavoltage Photon Beam. J Sains Nukl Malaysia. 2018;30(2):23-29.
]Search in Google Scholar
[
8. Abdul Rashid R, Zainal Abidin S, Khairil Anuar MA, et al. Radiosensitization effects and ROS generation by high Z metallic nanoparticles on human colon carcinoma cell (HCT116) irradiated under 150 MeV proton beam. OpenNano. 2019;4:100027. https://doi.org/10.1016/j.onano.2018.10002710.1016/j.onano.2018.100027
]Search in Google Scholar
[
9. Rahman WNWA. Gold nanoparticles: novel radiobiological dose enhancement studies for radiation therapy, synchrotron based microbeam and stereotactic radiotherapy. PhD. 2010.10.1063/1.3478186
]Search in Google Scholar
[
10. Verry C, Sancey L, Dufort S, et al. Treatment of multiple brain metastases using gadolinium nanoparticles and radiotherapy: NANORAD, a phase I study protocol. BMJ Open. 2019;9(2):1-6. https://doi.org/10.1136/bmjopen-2018-02359110.1136/bmjopen-2018-023591637753830755445
]Search in Google Scholar
[
11. Bonvalot S, Le Pechoux C, De Baere T, et al. First-in-human study testing a new radioenhancer using nanoparticles (NBTXR3) activated by radiation therapy in patients with locally advanced soft tissue sarcomas. Clin Cancer Res. 2017;23(4):908-917. https://doi.org/10.1158/1078-0432.CCR-16-129710.1158/1078-0432.CCR-16-129727998887
]Search in Google Scholar
[
12. Muhammad MA, Rashid RA, Lazim RM, Dollah N, Razak KA, Rahman WN. Evaluation of radiosensitization effects by platinum nanodendrites for 6 MV photon beam radiotherapy. Radiat Phys Chem. 2018;150:40-45. https://doi.org/10.1016/j.radphyschem.2018.04.01810.1016/j.radphyschem.2018.04.018
]Search in Google Scholar
[
13. Lazim RM, Rashid RA, Pham BTT, Hawkett BS, Geso M, Rahman WN. Radiation Dose Enhancement Effects of Superparamagnetic Iron Oxide nanoparticles to the T24 Bladder Cancer Cell Lines Irradiated with Megavoltage Photon Beam Radiotheray. J Sains Nukl Malaysia. 2018;30(2):30-38.
]Search in Google Scholar
[
14. Algethami M, Geso M, PIva T, et al. Radiation Dose Enhancement Using Bi2S3 Nanoparticles in Cultured Mouse PC3 Prostate and B16 Melanoma Cells. NanoWorld J. 2015;1(3). https://doi.org/10.17756/nwj.2015-01310.17756/nwj.2015-013
]Search in Google Scholar
[
15. Rajaee A, Wang S, Zhao L. Bismuth-based nanoparticles as radiosensitizer in low and high dose rate brachytherapy. Polish J Med Phys Eng. 2019;25(2):79-85. https://doi.org/10.2478/pjmpe-2019-001110.2478/pjmpe-2019-0011
]Search in Google Scholar
[
16. Zhou R, Wang H, Yang Y, et al. Tumor microenvironment-manipulated radiocatalytic sensitizer based on bismuth heteropolytungstate for radiotherapy enhancement. Biomaterials. 2019;189:11-22. https://doi.org/10.1016/j.biomaterials.2018.10.01610.1016/j.biomaterials.2018.10.01630384125
]Search in Google Scholar
[
17. Deng J, Xu S, Hu W, Xun X, Zheng L, Su M. Tumor targeted, stealthy and degradable bismuth nanoparticles for enhanced X-ray radiation therapy of breast cancer. Biomaterials. 2018;154:24-33. https://doi.org/10.1016/j.biomaterials.2017.10.04810.1016/j.biomaterials.2017.10.04829120816
]Search in Google Scholar
[
18. Sisin NNT, Abidin SZ, Yunus MA, Zin HM, Razak KA, Rahman WN. Evaluation of Bismuth Oxide Nanoparticles as Radiosensitizer for Megavoltage Radiotherapy. Int J Adv Sci Eng Inf Technol. 2019;9(4):1434-1443. https://doi.org/10.18517/ijaseit.9.4.721810.18517/ijaseit.9.4.7218
]Search in Google Scholar
[
19. Sisin NNT, Abdul Razak K, Zainal Abidin S, et al. Radiosensitization Effects by Bismuth Oxide Nanoparticles in Combination with Cisplatin for High Dose Rate Brachytherapy. Int J Nanomedicine. 2019;14:9941-9954.10.2147/IJN.S228919692722931908451
]Search in Google Scholar
[
20. Zhou R, Liu X, Wu Y, et al. Suppressing the radiation-induced corrosion of bismuth nanoparticles for enhanced synergistic cancer radiophototherapy. ACS Nano. 2020;14(10):13016-13029. https://doi.org/10.1021/acsnano.0c0437510.1021/acsnano.0c0437532898419
]Search in Google Scholar
[
21. Rahman WN, Bishara N, Ackerly T, et al. Enhancement of radiation effects by gold nanoparticles for superficial radiation therapy. Nanomedicine Nanotechnology, Biol Med. 2009;5:136-142. https://doi.org/10.1016/j.nano.2009.01.01410.1016/j.nano.2009.01.01419480049
]Search in Google Scholar
[
22. Rashid RA, Razak KA, Geso M, Abdullah R, Dollah N, Rahman WN. Radiobiological Characterization of the Radiosensitization Effects by Gold Nanoparticles for Megavoltage Clinical Radiotherapy Beams. Bionanoscience. 2018;8(3):713-722. https://doi.org/10.1007/s12668-018-0524-510.1007/s12668-018-0524-5
]Search in Google Scholar
[
23. Smith CL, Ackerly T, Best SP, et al. Determination of dose enhancement caused by gold-nanoparticles irradiated with proton, X-rays (kV and MV) and electron beams, using alanine/EPR dosimeters. Radiat Meas. 2015;82:122-128. https://doi.org/10.1016/j.radmeas.2015.09.00810.1016/j.radmeas.2015.09.008
]Search in Google Scholar
[
24. Rahman WN, Kadian SNM, Ab Rashid R, et al. Radiosensitization characteristic of superparamagnetic iron oxide nanoparticles in electron beam radiotherapy and brachytherapy. J Phys Conf Ser. 2019;1248:1-6. https://doi.org/10.1088/1742-6596/1248/1/01206810.1088/1742-6596/1248/1/012068
]Search in Google Scholar
[
25. Abidin SZ, Zulkifli ZA, Razak KA, Zin H, Yunus MA, Rahman WN. PEG coated bismuth oxide nanorods induced radiosensitization on MCF-7 breast cancer cells under irradiation of megavoltage radiotherapy beams. Mater Today Proc. 2019;16:1640-1645. https://doi.org/10.1016/j.matpr.2019.06.02910.1016/j.matpr.2019.06.029
]Search in Google Scholar
[
26. Abidin SZ, Razak KA, Zin H, et al. Comparison of clonogenic and PrestoBlue assay for radiobiological assessment of radiosensitization effects by bismuth oxide nanorods. Mater Today Proc. 2019;16:1646-1653. https://doi.org/10.1016/j.matpr.2019.06.03010.1016/j.matpr.2019.06.030
]Search in Google Scholar
[
27. Seabra A, Durán N. Nanotoxicology of Metal Oxide Nanoparticles. Metals (Basel). 2015;5(2):934-975. https://doi.org/10.3390/met502093410.3390/met5020934
]Search in Google Scholar
[
28. Chithrani BD, Ghazani AA, Chan WCW. Determining the Size and Shape Dependence of Gold Nanoparticles Uptake Into Mammalian Cells. Nano Lett. 2006;6(4):662-668. https://doi.org/10.1021/nl052396o10.1021/nl052396o16608261
]Search in Google Scholar
[
29. Venkatesh DN, Rao P. Nanoparticles For Cancer Treatment - A Comprehensive Review. World J Pharm Pharm Sci. 2016;5(9):481-499. https://doi.org/10.20959/wjpps20169-7513
]Search in Google Scholar
[
30. Koger B, Kirkby C. Dosimetric effects of polyethylene glycol surface coatings on gold nanoparticle radiosensitization. Phys Med Biol. 2017;92(8455). https://doi.org/10.1088/1361-6560/aa8e1210.1088/1361-6560/aa8e1228933351
]Search in Google Scholar
[
31. Zulkifli ZA, Razak KA, Rahman WNWA, Abidin SZ. Synthesis and Characterisation of Bismuth Oxide Nanoparticles using Hydrothermal Method: The Effect of Reactant Concentrations and application in radiotherapy. In: Journal of Physics: Conference Series. Vol 1082. IOP Publishing; 2018:1-7. https://doi.org/10.1088/1742-6596/1082/1/01210310.1088/1742-6596/1082/1/012103
]Search in Google Scholar
[
32. Zulkifli ZA, Razak KA, Rahman WNWA. The effect of reaction temperature on the particle size of bismuth oxide nanoparticles synthesized via hydrothermal method. In: 3rd International Concerence on the Science and Engineering of Materials (ICoSEM 2017) AIP Conference Proceedings 1958. Vol 020007. American Institute of Physics; 2018:1-5. https://doi.org/10.1063/1.503453810.1063/1.5034538
]Search in Google Scholar
[
33. Sisin NNT, Mat NFC, Abdullah R, Rahman WN. Baicalein-rich Fraction as a Potential Radiosensitizer or Radioprotective for HDR Brachytherapy: A Preliminary Study. J Nucl Relat Technol. 2020;18(1):9-16.
]Search in Google Scholar
[
34. Mukherjee SG, O’Claonadh N, Casey A, Chambers G. Comparative in vitro cytotoxicity study of silver nanoparticle on two mammalian cell lines. Toxicol Vitr. 2012;26(2):238-251. https://doi.org/10.1016/j.tiv.2011.12.00410.1016/j.tiv.2011.12.00422198051
]Search in Google Scholar
[
35. Swanepoel B, Nitulescu GM, Olaru OT, Venables L, van de Venter M. Anti-Cancer Activity of a 5-Aminopyrazole Derivative Lead Compound (BC-7) and Potential Synergistic Cytotoxicity with Cisplatin against Human Cervical Cancer Cells. Int J Mol Sci. 2019;20(22). https://doi.org/10.3390/ijms2022555910.3390/ijms20225559688836531703393
]Search in Google Scholar
[
36. Moghaddam AB, Moniri M, Azizi S, et al. Eco-friendly formulated zinc oxide nanoparticles: Induction of cell cycle arrest and apoptosis in the MCF-7 cancer cell line. Genes (Basel). 2017;8(10):281. https://doi.org/10.3390/genes810028110.3390/genes8100281566413129053567
]Search in Google Scholar
[
37. Cui L, Her S, Dunne M, et al. Significant Radiation Enhancement Effects by Gold Nanoparticles in Combination with Cisplatin in Triple Negative Breast Cancer Cells and Tumor Xenografts. Radiat Res. 2017;187(2):147-160. https://doi.org/10.1667/RR14578.110.1667/RR14578.128085639
]Search in Google Scholar
[
38. Sisin NNT, Razak KA, Abidin SZ, et al. Synergetic influence of bismuth oxide nanoparticles, cisplatin and baicalein-rich fraction on reactive oxygen species generation and radiosensitization effects for clinical radiotherapy beams. Int J Nanomedicine. 2020; (15):7805-7823. https://doi.org/10.2147%2FIJN.S26921410.2147/IJN.S269214756756533116502
]Search in Google Scholar
[
39. Hamida RS, Albasher G, Bin-Meferij MM. Oxidative stress and apoptotic responses elicited by nostoc-synthesized silver nanoparticles against different cancer cell lines. Cancers (Basel). 2020;12(8):2099. https://doi.org/10.3390/cancers1208209910.3390/cancers12082099746469332731591
]Search in Google Scholar
[
40. Alshatwi AA, Athinarayanan J, Periasamy VS, Prato M. Synthesis of copper-platinum nanoparticles induce apoptosis in THP-1 cells. IEEE-NANO 2015 - 15th Int Conf Nanotechnol. Published online 2015:1111-1113. https://doi.org/10.1109/NANO.2015.738881710.1109/NANO.2015.7388817
]Search in Google Scholar
[
41. Li Z, Liu J, Hu Y, et al. Biocompatible PEGylated bismuth nanocrystals: “All-in-one” theranostic agent with triple-modal imaging and efficient in vivo photothermal ablation of tumors. Biomaterials. 2017;141:284-295. https://doi.org/10.1016/j.biomaterials.2017.06.03310.1016/j.biomaterials.2017.06.03328709019
]Search in Google Scholar
[
42. Fam SY, Chee CF, Yong CY, Ho KL, Mariatulqabtiah AR, Tan WS. Stealth coating of Nanoparticles in drug-delivery systems. Nanomaterials. 2020;10(4):1-18. https://doi.org/10.3390/nano1004078710.3390/nano10040787722191932325941
]Search in Google Scholar
[
43. M. Christopher AMLS. Bio-inspired shielding strategies for NPs drug delivery. Physiol Behav. 2016;176(1):100–106. https://doi.org/10.1021/acs.molpharmaceut.8b00292.Bio
]Search in Google Scholar
[
44. Abakumov MA, Semkina AS, Skorikov AS, et al. Toxicity of iron oxide nanoparticles: Size and coating effects. J Biochem Mol Toxicol. 2018;32(12):1-6. https://doi.org/10.1002/jbt.2222510.1002/jbt.2222530290022
]Search in Google Scholar
[
45. Xue W, Liu Y, Zhang N, et al. Effects of core size and PEG coating layer of iron oxide nanoparticles on the distribution and metabolism in mice. Int J Nanomedicine. 2018;13:5719-5731. https://doi.org/10.2147/IJN.S16545110.2147/IJN.S165451616577230310275
]Search in Google Scholar
[
46. Zheng XJ, Chow JCL. Radiation dose enhancement in skin therapy with nanoparticle addition: A Monte Carlo study on kilovoltage photon and megavoltage electron beams. World J Radiol. 2017;9(2):63. https://doi.org/10.4329/wjr.v9.i2.6310.4329/wjr.v9.i2.63533450328298966
]Search in Google Scholar
[
47. Hwang C, Kim JM, Kim J. Influence of concentration, nanoparticle size, beam energy, and material on dose enhancement in radiation therapy. J Radiat Res. 2017;58(4):405-411. https://doi.org/10.1093/jrr/rrx00910.1093/jrr/rrx009556970428419319
]Search in Google Scholar
[
48. Mehrnia SS, Hashemi B, Mowla SJ, Arbabi A. Enhancing the effect of 4 MeV electron beam using gold nanoparticles in breast cancer cells. Phys Medica. 2017;35:18-24. https://doi.org/10.1016/j.ejmp.2017.02.01410.1016/j.ejmp.2017.02.01428285936
]Search in Google Scholar
[
49. Guo T. Physical, chemical and biological enhancement in X-ray nanochemistry. Phys Chem Chem Phys. 2019;21(29):15917-15931. https://doi.org/10.1039/c9cp03024g10.1039/C9CP03024G31309206
]Search in Google Scholar
[
50. Ghorbani M, Tabatabaei ZS, Vejdani NA, Vosoughi H, Knaup C. Effect of Tissue Composition on Dose Distribution in Electron Beam Radiotherapy. J Biomed Phys Eng. 2000;5(1).
]Search in Google Scholar
[
51. Sisin NNT, Rashid RA, Abdullah R, et al. GafchromicTM EBT3 Film Measurements of Dose Enhancement Effects by Metallic Nanoparticles for 192 Ir Brachytherapy, Proton, Photon and Electron Radiotherapy. Radiation. 2022;2:130-148.10.3390/radiation2010010
]Search in Google Scholar
[
52. Dayem AA, Hossain MK, Lee S Bin, et al. The role of reactive oxygen species (ROS) in the biological activities of metallic nanoparticles. Int J Mol Sci. 2017;18(120):1-21. https://doi.org/10.3390/ijms1801012010.3390/ijms18010120529775428075405
]Search in Google Scholar
[
53. Stewart CAC. An investigation into the tailoring of bismuth oxide nanoceramic with a biomedical application as a high Z radiation enhancer for cancer therapy. MSc. Published online 2014.
]Search in Google Scholar
[
54. Alan Mitteer R, Wang Y, Shah J, et al. Proton beam radiation induces DNA damage and cell apoptosis in glioma stem cells through reactive oxygen species. Sci Rep. 2015;5(13961):1-12. https://doi.org/10.1038/srep1396110.1038/srep13961456480126354413
]Search in Google Scholar
[
55. Xue J, Yu C, Sheng W, et al. The Nrf2/GCH1/BH4 Axis Ameliorates Radiation-Induced Skin Injury by Modulating the ROS Cascade. J Invest Dermatol. 2017;137(10):2059-2068. https://doi.org/10.1016/j.jid.2017.05.01910.1016/j.jid.2017.05.01928596000
]Search in Google Scholar
[
56. Liu G, Li Y, Yang L, et al. Cytotoxicity study of polyethylene glycol derivatives. RSC Adv. 2017;7(30):18252-18259. https://doi.org/10.1039/c7ra00861a10.1039/C7RA00861A
]Search in Google Scholar
[
57. Zhang T, Chen X, Xiao C, Zhuang X, Chen X. Synthesis of a phenylboronic ester-linked PEG-lipid conjugate for ROS-responsive drug delivery. Polym Chem. 2017;8(40):6209-6216. https://doi.org/10.1039/c7py00915a10.1039/C7PY00915A
]Search in Google Scholar
[
58. Cui L. Optimization of Gold Nanoparticle Radiosensitizers for Cancer Therapy Optimization of Gold Nanoparticle Radiosensitizers. PhD. Published online 2016.
]Search in Google Scholar
[
59. Zhu C, Hu W, Wu H, Hu X. No evident dose-response relationship between cellular ROS level and its cytotoxicity - A paradoxical issue in ROS-based cancer therapy. Sci Rep. 2014;4(5029):1-10. https://doi.org/10.1038/srep0502910.1038/srep05029403025724848642
]Search in Google Scholar
[
60. Choi C, Son A, Lee HS, Lee YJ, Park HC. Radiosensitization by Marine Sponge Agelas sp. Extracts in Hepatocellular Carcinoma Cells with Autophagy Induction. Sci Rep. 2018;8(6317):1-10. https://doi.org/10.1038/s41598-018-24745-w10.1038/s41598-018-24745-w591039729679028
]Search in Google Scholar
[
61. Lipiec E, Bambery KR, Heraud P, et al. Synchrotron FTIR shows evidence of DNA damage and lipid accumulation in prostate adenocarcinoma PC-3 cells following proton irradiation. J Mol Struct. 2014;1073:134-141. https://doi.org/10.1016/j.molstruc.2014.04.05610.1016/j.molstruc.2014.04.056
]Search in Google Scholar
[
62. Chen Y, Li N, Wang J, et al. Enhancement of mitochondrial ROS accumulation and radiotherapeutic efficacy using a Gd-doped titania nanosensitizer. Theranostics. 2019;9(1):167-178. https://doi.org/10.7150/thno.2803310.7150/thno.28033633280230662560
]Search in Google Scholar