Acceso abierto

Studies on the significance of secretory IgA antibodies in the pathogenesis and clinical course of enterobiasis in infected persons from Bulgaria: preliminary findings

,

,

,

,

,

,

,

,

y

31 dic 2024

Studies on the significance of secretory IgA antibodies in the pathogenesis and clinical course of enterobiasis in infected persons from Bulgaria: preliminary findings's Cover Image

Volumen 61 (2024): Edición 4 (Diciembre 2024)

Acerca de este artículo

Artículo anterior

Artículo siguiente

Cite

Compartir

Descargar portada

Publicado en línea: 31 dic 2024

Páginas: 277 - 285

Recibido: 23 ago 2024

Aceptado: 28 nov 2024

DOI: https://doi.org/10.2478/helm-2024-0034

Palabras clave
secretory IgA antibodies, gastrointestinal immunity, enterobiasis

© 2024 E. Kaneva et al., published by Sciendo

This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Distribution of secretory IgA values in clinically healthy controls by age group, gender, and the reference range of the diagnostic kit used.

Distribution of secretory IgA values in persons with enterobiasis by age group, gender, and reference range of the diagnostic kit used.

Concentrations of the fecal secretory IgA antibodies in healthy individuals and patients with enterobiasis. To establish statistically significant differences in the values of SIgA, a Mann-Whitney test was performed (exact P value = 0.4991).

Demographic data and SIgA levels in both groups studied: infected and non-infected

Examined persons	without evidence of enterobiasis and/or other intestinal parasitic infection				with laboratory-confirmed enterobiasis

	Children & adolescents	Adults	Male	Female	Children & adolescents	Adults	Male	Female

No	34	6	19	21	97	5	46	56

SIgA values (µg/ml)
Minimum	27.50	27.50	27.50	27.50	27.50	37.50	27.50	27.50
Maximum	8999	1357	8999	4839	13916	981.5	13916	9704
Range	8971	1330	8971	4811	13889	944.0	13889	9676
Mean	1978	474,3	2060	1473	1815	481.7	1901	1625
Std. Deviation	2162	608.5	2561	1518	2562	398.2	2774	2300
Lower 95% CI of mean	1223	−164.3	825.8	782.5	1299	−12.84	1078	1009
Upper 95% CI of mean	2732	1113	3295	2164	2331	976.1	2725	2241

Mann Whitney test	exact P value = 0.0295*		exact P value = 0.5915		exact P value = 0.2808		exact P value = 0.4568

Mean values of intestinal SIgA concentrations in the studied children, relative to the reported clinical symptom_

	No	SIgA mean value (μg/ml)	Std. Deviation	SIgA min. value (μg/ml)	SIgA max. value (μg/ml)
Asymptomatic persons	61	1 588.54	2046	27.5	9 422.44

Patients with symptoms:	36	2 198.74	3254	27.5	13 916.00

perianal itching	17	3 559.54	3949	27.5	13 916.00
abdominal pain	10	1 383.66	2493	27.5	8 064.51
diarrhea	5	545.53	654	27.5	1 488.38
bruxism	3	556.25	N/A	137.50	813.75
eosinophilia	1	409.40	366	409.40	409.40

ANOVA test, P value = 0.049

Idioma:: Inglés

Calendario de la edición:: 4 veces al año
Temas de la revista:: Ciencias de la vida, Zoología, Ecología, Ciencias de la vida, otros, Medicina, Medicina Clínica, Microbiología, virología y epidemiología

RSS Feed de revista