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Impact of smoking cessation counseling among acute myocardial infarction patients on post-hospitalization mortality rates: a systematic review


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Figure 1

Flow of studies through the review process.
Flow of studies through the review process.

Reported mortality rates in each study.

Authors 30-d mortality rate 60-d mortality rate 1-year mortality rate
Bucholz et al., (2016)8 No available data No available data Mortality risk reduction of 18%, hazard ratio of (0.819, 95%), confidence interval of (0.75–0.895)
Brown et al., (2004)16 Mortality rate risk reduction was 23% hazard ratio (0.774, 95%), confidence interval of (0.621–0.964)16 No available data No available data
Van Spall et al., (2007)19 No available data No available data Mortality rate risk reduction of 37%, hazard ratio of (0.41, 95%), confidence interval of (0.3–0.56)
Houston et al., (2005)17 The relative 30 d mortality rate risk reduction was reported to be 19%, hazard ratio of (0.81, 95%), confidence interval of (0.65–0.99). The relative 60 d mortality rate risk reduction was reported to be 19%, hazard ratio of (0.81, 95%), confidence interval of (0.65–0.94) Mortality rate risk reduction was 14%, hazard ratio of (0.86, 95%), confidence interval of (0.79–0.94)

Reported SCC rates.

Study N (%) received SCC N (%) did not receive SCC
Bucholz et al. (2016)8 5695 (41.2%) 8120 (58.8%)
Brown et al. (2004)16 133 (33.9%) 259 (66.1%)
Van Spall et al. (2007)19 1830 (52.1%) 1681 (47.9%)
Houston et al. (2005)17 6875 (41.0%) 9868 (59.0%)

Studies of the effectiveness of smoking cessation counseling on mortality rate.

Author Site & participants Demographics Intervention and objectives Design Measure of mortality Mortality-related results Conclusion
Van Spall, Chong, & Tu, (2007)19 83 teaching and community hospitals in Ontario, CanadaN = 9041, patients presenting with AMI Mean age 65 years.Male 67%.History of DM and HTN (69%).Smoker 67% (n = 6094).Smoker counseled 1830 (52.1%). No intervention; medical record review.Determine the associations between inpatient SCC and survival rate. Retrospective cohort analysis, recruited from EFFECT study. Multivariate Cox proportional hazards regression model. Reduction in mortality was significantly associated with inpatient SCC (hazard ratio 0.63, 95% CI, 0.44–0.90). The SCC for inpatients post-MI is independently associated with a vital mortality advantage.
Mohiuddin et al. (2007)18 University-affiliated teaching hospitalN = 209 Intervention group:Mean age 54 yearsMale 69%.White (77%),History of DM and HTN (56%).Control group:Mean age 55.5 yearsMale 56%.History of DM and HTN (63%). Counseling weekly for 60 min for a minimum of 3 months, delivered by a trained tobacco cessation counselor. A randomized controlled trial, un-blind trial Mortality was computed and compared using the Kaplan–Meier method. All-cause mortality rate was 2.8% among the intervention group, compared with 12.0% in the usual care group. The absolute risk reduction in mortality was 9.2%. Smokers recovering from acute coronary syndrome should receive intensive SCC counseling and drugs treatment for at least 3 months.
Bucholz, Beckman, Kiefe, & Krumholz, (2017)8 Acute care, non-governmental hospitals in the US.N = 13,815 smokers with AMI. Mean age 72 years.Male 57%.White (76.8%).History of DM and HTN (79%).Smoker counseled (41.2%) Examine the differences in life expectancy after AMI between counseled and non-counseled smokers. Retrospective study obtained from the Cooperative Cardiovascular Project. Marginal Cox proportional hazards models. Counseled smokers had lower crude mortality than non-counseled smokers. *SCC for elderly patients with AMI is associated with long life expectancy and gains in life years.
Houston et al. (2005)17 Inpatients from 2971 acute care hospitals in the US.N = 16,743 smokers with AMI. Male 57%.White (92.2%).History of DM (22%).Smoker 100% (n = 16,743).Smoker counseled (41.1%). No intervention reported. The SCC was attained through medical record review, as if the patient received counseling, was shown a smoking cessation (SC) video, or given brochures on SC.Assess the difference in immediate (30 and 60 d after admission) and late (2-year) mortality rates Cross-sectional survey, recruited from the Cooperative Cardiovascular Project. Kaplan–Meier survival curves; Multivariable adjustments using Cox proportion hazards models. Smokers who received SCC had lower 30-d, 60-d, and 2-year mortality compared to non-counseled smokers.Within 30 d, the maximum decline in relative hazard (19%) was seen. There is a positive association of SCC with survival.
Brown et al. (2004)16 117 North Carolina acute care facilities.N = 788 smoker with confirmed AMI. Mean age 72 years.Male 59.8%.White (85.8%).History of DM and HTN (83.5%).*Smokers 100% (n = 788).*Smokers counseled (40%). No intervention.Medical record documentation review.Examine the effect of inpatient advice or SCC on the risk of all-cause 5-year mortality among older patients hospitalized with coronary heart disease. Cross-sectional survey, recruited from the Cooperative Cardiovascular Project. Cox proportional hazard regression The 5-years related mortality were lower among patients who were given counseling.All-cause mortality was reduced.After adjusting for socio-demographic variables, improving the survival among inpatients was associated with providing SCC (relative hazard, 0.78; 95% CI, 0.63–0.97). Implementing SCC that reaches all patients, including the elderly smokers, is required.
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Medicine, Assistive Professions, Nursing