Acceso abierto

Expression of the Non-classical HLA-E, -F, -G Molecules in the Tumour Microenvironment


Cite

Siegel RL, Miller KD, Fuchs HE, et al. Cancer statistics. CA Cancer J Clin. 2022;72(1):7–33. SiegelRL MillerKD FuchsHE Cancer statistics CA Cancer J Clin. 2022 72 1 7 33 Search in Google Scholar

Cancer 2020. Available from: https://www.who.int/news-room/fact-sheets/detail/cancer. Cancer 2020 Available from: https://www.who.int/news-room/fact-sheets/detail/cancer. Search in Google Scholar

da Silva GBRF, Silva TGA, Duarte RA, et al. Expression of the classical and nonclassical HLA molecules in breast cancer. Int J Breast Cancer. 2013;1–9. da SilvaGBRF SilvaTGA DuarteRA Expression of the classical and nonclassical HLA molecules in breast cancer Int J Breast Cancer. 2013 1 9 Search in Google Scholar

Seliger B, Kloor M, Ferrone S. HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance. Oncoimmunology. 2017;6(2):1–10. SeligerB KloorM FerroneS. HLA class II antigen-processing pathway in tumors: Molecular defects and clinical relevance Oncoimmunology. 2017 6 2 1 10 Search in Google Scholar

Niranjana AN, Gonzalez F. Non-classical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum. Nat Immunol. 2012;13(6):579–586. NiranjanaAN GonzalezF. Non-classical MHC class Ib-restricted cytotoxic T cells monitor antigen processing in the endoplasmic reticulum Nat Immunol. 2012 13 6 579 586 Search in Google Scholar

Bukur J, Jasinski S, Seliger B. The role of classical and non-classical HLA class I antigens in human tumors. Semin Cancer Biol. 2012;22(4):350–358. BukurJ JasinskiS SeligerB. The role of classical and non-classical HLA class I antigens in human tumors Semin Cancer Biol. 2012 22 4 350 358 Search in Google Scholar

Adams EJ, Luoma AM. The adaptable major histocompatibility complex (MHC) fold: Structure and function of nonclassical and mhc class I-like molecules. Annual Review of Immunology. 2013; 31:529–561. AdamsEJ LuomaAM. The adaptable major histocompatibility complex (MHC) fold: Structure and function of nonclassical and mhc class I-like molecules Annual Review of Immunology. 2013 31 529 561 Search in Google Scholar

Robinson J, Barker DJ, Georgiou X, et al. IPD-IMGT/HLA Database. Nucleic Acids Res. 2020; 48(D1):948–955. RobinsonJ BarkerDJ GeorgiouX IPD-IMGT/HLA Database Nucleic Acids Res. 2020 48 D1 948 955 Search in Google Scholar

Morandi F, Pistoia V. Interactions between HLA-G and HLA-E in physiological and pathological conditions. Front Immunol. 2014;5:1–6. MorandiF PistoiaV. Interactions between HLA-G and HLA-E in physiological and pathological conditions Front Immunol. 2014 5 1 6 Search in Google Scholar

Tronik-Le Roux D, Renard J, Vérine J, et al. Novel landscape of HLA-G isoforms expressed in clear cell renal cell carcinoma patients. Molecular Oncology. 2017;11:561–578. Tronik-Le RouxD RenardJ VérineJ Novel landscape of HLA-G isoforms expressed in clear cell renal cell carcinoma patients Molecular Oncology. 2017 11 561 578 Search in Google Scholar

Zhang Y, Yu S, Han Y. Human leucocyte antigen-G expression and polymorphisms promote cancer development and guide cancer diagnosis/treatment. Oncol Lett. 2018;15:699–709. ZhangY YuS HanY. Human leucocyte antigen-G expression and polymorphisms promote cancer development and guide cancer diagnosis/treatment Oncol Lett. 2018 15 699 709 Search in Google Scholar

Campoli M, Ferrone S. HLA antigen and NK cell activating ligand expression in malignant cells: A story of loss or acquisition. Semin Immunopathol. 2011;33:321–334. CampoliM FerroneS. HLA antigen and NK cell activating ligand expression in malignant cells: A story of loss or acquisition Semin Immunopathol. 2011 33 321 334 Search in Google Scholar

Reimers MS, Engels CC, Putter H, et al. Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: A retrospective cohort study. BMC Cancer. 2014;14(1):1–12. ReimersMS EngelsCC PutterH Prognostic value of HLA class I, HLA-E, HLA-G and Tregs in rectal cancer: A retrospective cohort study BMC Cancer. 2014 14 1 1 12 Search in Google Scholar

Borst L, van der Burg SH, van Hall T. The NKG2A-HLA-E axis as a novel checkpoint in the tumor microenvironment. Clin Cancer Res. 2021;26(21):5549–5556. BorstL van der BurgSH van HallT. The NKG2A-HLA-E axis as a novel checkpoint in the tumor microenvironment Clin Cancer Res. 2021 26 21 5549 5556 Search in Google Scholar

Kamiya T, Seow SV, Wong D. Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells. J Clin Invest. 2019;129(5):2094–2106. KamiyaT SeowSV WongD. Blocking expression of inhibitory receptor NKG2A overcomes tumor resistance to NK cells J Clin Invest. 2019 129 5 2094 2106 Search in Google Scholar

Wagner B, da Silva Nardi F, Schramm S, et al. HLA-E allelic genotype correlates with HLA-E plasma levels and predicts early progression in chronic lymphocytic leukemia. Cancer. 2017;123(5):814–823. WagnerB da Silva NardiF SchrammS HLA-E allelic genotype correlates with HLA-E plasma levels and predicts early progression in chronic lymphocytic leukemia Cancer. 2017 123 5 814 823 Search in Google Scholar

Lin A, Yan WH. The emerging roles of human leukocyte antigen-F in immune modulation and viral infection. Front Immunol. 2019;10:1–7. LinA YanWH. The emerging roles of human leukocyte antigen-F in immune modulation and viral infection Front Immunol. 2019 10 1 7 Search in Google Scholar

Lin A, Zhang X, Ruan YY, et al. HLA-F expression is a prognostic factor in patients with non-small-cell lung cancer. Lung Cancer. 2011;74(3):504–509. LinA ZhangX RuanYY HLA-F expression is a prognostic factor in patients with non-small-cell lung cancer Lung Cancer. 2011 74 3 504 509 Search in Google Scholar

Loustau M, Anna F, Dréan R, et al. HLA-G neo-expression on tumors. Front Immunol. 2020;11:1–15. LoustauM AnnaF DréanR HLA-G neo-expression on tumors Front Immunol. 2020 11 1 15 Search in Google Scholar

Lin A, Yan WH. Human leukocyte antigen-G (HLA-G) expression in cancers: Roles in immune evasion, metastasis and target for therapy. Mol Med. 2015;21:782–791. LinA YanWH. Human leukocyte antigen-G (HLA-G) expression in cancers: Roles in immune evasion, metastasis and target for therapy Mol Med. 2015 21 782 791 Search in Google Scholar

Rouas-Freiss N, Moreau P, LeMaoult J, et al. The dual role of HLA-G in cancer. J Immunol Res. 2014;1–10. Rouas-FreissN MoreauP LeMaoultJ The dual role of HLA-G in cancer J Immunol Res. 2014 1 10 Search in Google Scholar

Liu L, Wang L, Zhao L, et al. The role of HLA-G in tumor escape: Manipulating the phenotype and function of immune cells. Front Oncol. 2020;10:1–11. LiuL WangL ZhaoL The role of HLA-G in tumor escape: Manipulating the phenotype and function of immune cells Front Oncol. 2020 10 1 11 Search in Google Scholar

Paul P, Rouas-Freiss N, Khalil-Daher I, et al. HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance. Proc Natl Acad Sci USA. 1998;95(8):4510–4515. PaulP Rouas-FreissN Khalil-DaherI HLA-G expression in melanoma: A way for tumor cells to escape from immunosurveillance Proc Natl Acad Sci USA. 1998 95 8 4510 4515 Search in Google Scholar

Derré L, Corvaisier M, Charreau B, et al. Expression and release of HLA-E by melanoma cells and melanocytes: Potential impact on the response of cytotoxic effector cells. J Immunol. 2006; 177(5):3100–3107. DerréL CorvaisierM CharreauB Expression and release of HLA-E by melanoma cells and melanocytes: Potential impact on the response of cytotoxic effector cells J Immunol. 2006 177 5 3100 3107 Search in Google Scholar

Allard M, Oger R, Vignard V, et al. Serum soluble HLA-E in melanoma: A new potential immune-related marker in cancer. PLoS One. 2011;6:6. AllardM OgerR VignardV Serum soluble HLA-E in melanoma: A new potential immune-related marker in cancer PLoS One. 2011 6 6 Search in Google Scholar

Urosevic M, Dummer R. HLA-G in skin cancer: A wolf in sheep’s clothing? Hum Immunol. 2003; 64(11):1073–1080. UrosevicM DummerR. HLA-G in skin cancer: A wolf in sheep’s clothing? Hum Immunol. 2003 64 11 1073 1080 Search in Google Scholar

Urosevic M, Kempf W, Zagrodnik B, et al. HLA-G expression in basal cell carcinomas of the skin recurring after radiotherapy. Clin Exp Dermatol. 2005;30(4):422–425. UrosevicM KempfW ZagrodnikB HLA-G expression in basal cell carcinomas of the skin recurring after radiotherapy Clin Exp Dermatol. 2005 30 4 422 425 Search in Google Scholar

Zheng J, Xu C, Chu D, et al. Human leukocyte antigen G is associated with esophageal squamous cell carcinoma progression and poor prognosis. Immunol Lett. 2014;161(1):13–19. ZhengJ XuC ChuD Human leukocyte antigen G is associated with esophageal squamous cell carcinoma progression and poor prognosis Immunol Lett. 2014 161 1 13 19 Search in Google Scholar

Yie SM, Yang H, Ye SR, et al. Expression of HLA-G is associated with prognosis in esophageal squamous cell carcinoma. Am J Clin Pathol. 2007;128(6):1002–1009. YieSM YangH YeSR Expression of HLA-G is associated with prognosis in esophageal squamous cell carcinoma Am J Clin Pathol. 2007 128 6 1002 1009 Search in Google Scholar

Julie B, Charles P, Wisnivesky J. Global epidemiology of lung cancer. Ann Glob Heal. 2019;1–16. JulieB CharlesP WisniveskyJ. Global epidemiology of lung cancer Ann Glob Heal. 2019 1 16 Search in Google Scholar

Yazdi MT, van Riet S, van Schadewijk A, et al. The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma. Oncotarget. 2016;7(3):3477–3488. YazdiMT van RietS van SchadewijkA The positive prognostic effect of stromal CD8+ tumor-infiltrating T cells is restrained by the expression of HLA-E in non-small cell lung carcinoma Oncotarget. 2016 7 3 3477 3488 Search in Google Scholar

Llovet J, Kelley R, Villanueva A. Hepatocellular carcinoma. Nat Rev Dis Prim. 2021;7(6):1–28. LlovetJ KelleyR VillanuevaA. Hepatocellular carcinoma Nat Rev Dis Prim. 2021 7 6 1 28 Search in Google Scholar

Xu Y, Han H, Zhang F. Lesion human leukocyte antigen-F expression is associated with a poor prognosis in patients with hepatocellular carcinoma. Oncol Lett. 2015;9:300–304. XuY HanH ZhangF. Lesion human leukocyte antigen-F expression is associated with a poor prognosis in patients with hepatocellular carcinoma Oncol Lett. 2015 9 300 304 Search in Google Scholar

Crew K, Neugut A. Epidemiology of gastric cancer. World J Gastroenterol. 2006;12(3):354–362. CrewK NeugutA. Epidemiology of gastric cancer World J Gastroenterol. 2006 12 3 354 362 Search in Google Scholar

Murdaca G, Calamaro P, Lantieri F, et al. HLA-G expression in gastric carcinoma: Clinicopathological correlations and prognostic impact. Virchows Arch. 2018;473(4):425–433. MurdacaG CalamaroP LantieriF HLA-G expression in gastric carcinoma: Clinicopathological correlations and prognostic impact Virchows Arch. 2018 473 4 425 433 Search in Google Scholar

Zeestraten ECM, Reimers MS, Saadatmand S, et al. Combined analysis of HLA class I, HLA-E and HLA-G predicts prognosis in colon cancer patients. Br J Cancer. 2014;110(2):459–468. ZeestratenECM ReimersMS SaadatmandS Combined analysis of HLA class I, HLA-E and HLA-G predicts prognosis in colon cancer patients Br J Cancer. 2014 110 2 459 468 Search in Google Scholar

Guo ZY, Lv YG, Wang L, et al. Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients. Cell Immunol. 2015;293(1):10–16. GuoZY LvYG WangL Predictive value of HLA-G and HLA-E in the prognosis of colorectal cancer patients Cell Immunol. 2015 293 1 10 16 Search in Google Scholar

Ye S, Yang H, Li K. Human leukocyte antigen G expression: As a significant prognostic indicator for patients with colorectal cancer. Mod Pathol. 2007;20:375–383. YeS YangH LiK. Human leukocyte antigen G expression: As a significant prognostic indicator for patients with colorectal cancer Mod Pathol. 2007 20 375 383 Search in Google Scholar

Breastcancer.org. https://www.breastcancer.org/symptoms/understand_bc/statistics. Breastcancer.org https://www.breastcancer.org/symptoms/understand_bc/statistics. Search in Google Scholar

Menier C, Rouas-Freiss N, Favier B, et al. Recent advances on the non-classical major histocompatibility complex class i HLA-G molecule. Tissue Antigens. 2010;75(3):201–206. MenierC Rouas-FreissN FavierB Recent advances on the non-classical major histocompatibility complex class i HLA-G molecule Tissue Antigens. 2010 75 3 201 206 Search in Google Scholar

de Kruijf EM, Sajet A, van Nes JGH, et al. HLA-E and HLA-G expression in classical HLA class I-negative tumors is of prognostic value for clinical outcome of early breast cancer patients. J Immunol. 2010;185(12):7452–7459. de KruijfEM SajetA van NesJGH HLA-E and HLA-G expression in classical HLA class I-negative tumors is of prognostic value for clinical outcome of early breast cancer patients J Immunol. 2010 185 12 7452 7459 Search in Google Scholar

Harada A, Ishigami S, Kijima Y, et al. Clinical implication of human leukocyte antigen (HLA)-F expression in breast cancer. Pathol Int. 2015;65(11):569–574. HaradaA IshigamiS KijimaY Clinical implication of human leukocyte antigen (HLA)-F expression in breast cancer Pathol Int. 2015 65 11 569 574 Search in Google Scholar

Gooden M, Lampen M, Jordanova ES, et al. HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8 + T lymphocytes. Proc Natl Acad Sci USA. 2011;108(26):10656–10661. GoodenM LampenM JordanovaES HLA-E expression by gynecological cancers restrains tumor-infiltrating CD8 + T lymphocytes Proc Natl Acad Sci USA. 2011 108 26 10656 10661 Search in Google Scholar

Van Esch EMG, Tummers B, Baartmans V, et al. Alterations in classical and nonclassical HLA expression in recurrent and progressive HPV-induced usual vulvar intraepithelial neoplasia and implications for immunotherapy. Int J Cancer. 2014;135(4):830–842. Van EschEMG TummersB BaartmansV Alterations in classical and nonclassical HLA expression in recurrent and progressive HPV-induced usual vulvar intraepithelial neoplasia and implications for immunotherapy Int J Cancer. 2014 135 4 830 842 Search in Google Scholar

Centers for Disease Control and Prevention. Ovarian cancer statistics. https://www.cdc.gov/cancer/ovarian/statistics/. Centers for Disease Control and Prevention Ovarian cancer statistics https://www.cdc.gov/cancer/ovarian/statistics/. Search in Google Scholar

Babay W, Ben Yahia H, Boujelbene N, et al. Clinicopathologic significance of HLA-G and HLA-E molecules in Tunisian patients with ovarian carcinoma. Hum Immunol. 2018;79(6):463–470. BabayW Ben YahiaH BoujelbeneN Clinicopathologic significance of HLA-G and HLA-E molecules in Tunisian patients with ovarian carcinoma Hum Immunol. 2018 79 6 463 470 Search in Google Scholar

Kanevskiy L, Erokhina S, Kobyzeva P, et al. Dimorphism of HLA-E and its disease association. Int J Mol Sci. 2019;20(21):1–16. KanevskiyL ErokhinaS KobyzevaP Dimorphism of HLA-E and its disease association Int J Mol Sci. 2019 20 21 1 16 Search in Google Scholar

Guan J, Xie L, Luo X. The prognostic significance of estrogen and progesterone receptors in grade I and II endometrioid endometrial adenocarcinoma: Hormone receptors in risk stratification. Gynecol Oncol. 2019;30(1):1–14. GuanJ XieL LuoX. The prognostic significance of estrogen and progesterone receptors in grade I and II endometrioid endometrial adenocarcinoma: Hormone receptors in risk stratification Gynecol Oncol. 2019 30 1 1 14 Search in Google Scholar

Bijen CBM, Bantema-Joppe EJ, De Jong RA, et al. The prognostic role of classical and nonclassical MHC class I expression in endometrial cancer. Int J Cancer. 2010;126(6):1417–1427. BijenCBM Bantema-JoppeEJ De JongRA The prognostic role of classical and nonclassical MHC class I expression in endometrial cancer Int J Cancer. 2010 126 6 1417 1427 Search in Google Scholar

Haque A, Banik NL, Ray SK. Molecular alterations in glioblastoma: Potential targets for immunotherapy. Prog Mol Bio and Trans Sci. 2011;98:187–234 HaqueA BanikNL RaySK. Molecular alterations in glioblastoma: Potential targets for immunotherapy Prog Mol Bio and Trans Sci. 2011 98 187 234 Search in Google Scholar

Wu Z, Liang J, Wang Z, et al. HLA-E expression in diffuse glioma: Relationship with clinicopathological features and patient survival. BMC Neurol. 2020;20(1):1–7. WuZ LiangJ WangZ HLA-E expression in diffuse glioma: Relationship with clinicopathological features and patient survival BMC Neurol. 2020 20 1 1 7 Search in Google Scholar

Bukova M, Kluckova K, Kozak J. HLA-G 14 bp ins/del polymorphism, plasma level of soluble HLA-G and association with IL-6/IL-10 ratio and survival of glioma patients. Prepr. 2021;1–23. BukovaM KluckovaK KozakJ. HLA-G 14 bp ins/del polymorphism, plasma level of soluble HLA-G and association with IL-6/IL-10 ratio and survival of glioma patients Prepr. 2021 1 23 Search in Google Scholar

Wagner B, Nardi F, Schramm S. HLA-E allelic genotype correlates with HLA-E plasma levels and predicts early progression in chronic lymphocytic leukemia. Wiley Online Libr. 2016;814–823. WagnerB NardiF SchrammS. HLA-E allelic genotype correlates with HLA-E plasma levels and predicts early progression in chronic lymphocytic leukemia Wiley Online Libr. 2016 814 823 Search in Google Scholar

Nückel H, Rebmann V, Dürig J, et al. HLA-G expression is associated with an unfavorable outcome and immunodeficiency in chronic lymphocytic leukemia. Blood. 2005;105(4):1694–1698. NückelH RebmannV DürigJ HLA-G expression is associated with an unfavorable outcome and immunodeficiency in chronic lymphocytic leukemia Blood. 2005 105 4 1694 1698 Search in Google Scholar

Yan WH, Lin A, Chen BG, et al. Unfavourable clinical implications for HLA-G expression in acute myeloid leukaemia. J Cell Mol Med. 2008;12(3):889–898. YanWH LinA ChenBG Unfavourable clinical implications for HLA-G expression in acute myeloid leukaemia J Cell Mol Med. 2008 12 3 889 898 Search in Google Scholar

Sebti Y, Le Maux A, Gros F, et al. Expression of functional soluble human leucocyte antigen-G molecules in lymphoproliferative disorders. Br J Haematol. 2007;138(2):202–212. SebtiY Le MauxA GrosF Expression of functional soluble human leucocyte antigen-G molecules in lymphoproliferative disorders Br J Haematol. 2007 138 2 202 212 Search in Google Scholar

Jesionek-Kupnicka D, Bojo M, Prochorec-Sobieszek M. HLA-G and MHC class II protein expression in diffuse large B-cell lymphoma. Blood. 2016;64(3):225–240. Jesionek-KupnickaD BojoM Prochorec-SobieszekM. HLA-G and MHC class II protein expression in diffuse large B-cell lymphoma Blood. 2016 64 3 225 240 Search in Google Scholar

Diepstra A, Poppema S, Boot M, et al. HLA-G protein expression as a potential immune escape mechanism in classical Hodgkin’s lymphoma. Tissue Antigens. 2008;71(3):219–226. DiepstraA PoppemaS BootM HLA-G protein expression as a potential immune escape mechanism in classical Hodgkin’s lymphoma Tissue Antigens. 2008 71 3 219 226 Search in Google Scholar

Caocci G, Greco M, Fanni D, et al. HLA-G expression and role in advanced-stage classical Hodgkin lymphoma. Eur J Histochem. 2016;60(2):1–6. CaocciG GrecoM FanniD HLA-G expression and role in advanced-stage classical Hodgkin lymphoma Eur J Histochem. 2016 60 2 1 6 Search in Google Scholar

Martin P, Krsnik I, Navarro B. HLA allele E*01:01 is associated with a reduced risk of EBV-related classical Hodgkin lymphoma independently of HLA-A*01/*02. PLoS One. 2015;1–13. MartinP KrsnikI NavarroB. HLA allele E*01:01 is associated with a reduced risk of EBV-related classical Hodgkin lymphoma independently of HLA-A*01/*02 PLoS One. 2015 1 13 Search in Google Scholar

Amiot L, Ferrone S, Grosse-Wilde H, et al. Biology of HLA-G in cancer: A candidate molecule for therapeutic intervention? Cell Mol Life Sci. 2011;68(3):417–431. AmiotL FerroneS Grosse-WildeH Biology of HLA-G in cancer: A candidate molecule for therapeutic intervention? Cell Mol Life Sci. 2011 68 3 417 431 Search in Google Scholar

Adolf IC, Almars A, Dharsee N, et al. HLA-G and single nucleotide polymorphism (SNP) associations with cancer in African populations: Implications in personal medicine. Genes Dis. 2021;9(5):1220–1233. AdolfIC AlmarsA DharseeN HLA-G and single nucleotide polymorphism (SNP) associations with cancer in African populations: Implications in personal medicine Genes Dis. 2021 9 5 1220 1233 Search in Google Scholar

Belén Palma M, Tronik-Le Roux D, Amín G, et al. HLA-G gene editing: A novel therapeutic alternative in cancer immunotherapy. bioRxiv. 2021. https://doi.org/10.1101/2021.01.21.427294. Belén PalmaM Tronik-Le RouxD AmínG HLA-G gene editing: A novel therapeutic alternative in cancer immunotherapy bioRxiv 2021 https://doi.org/10.1101/2021.01.21.427294. Search in Google Scholar

eISSN:
1792-362X
Idioma:
Inglés
Calendario de la edición:
4 veces al año
Temas de la revista:
Medicine, Clinical Medicine, Internal Medicine, Haematology, Oncology